三甲基氯化锡

4篇引用文献

≥97%

CAS编号: 1066-45-1
分子式: C₃H₉ClSn
分子量: 199.27
Beilstein号: 3535111
EC号: 213-917-8
MDL号: MFCD00000520
PubChem编号: 14016

有货

库存信息

关闭

库存信息

关闭

库存信息

关闭

货号 (SKU)	包装规格	是否现货
T113979-1g	1g	现货
T113979-5g	5g	现货
T113979-25g	25g	现货

查看相关系列

元素分类的化合物 (2082) 有机锡 (34)

Skip to the end of the images gallery

Skip to the beginning of the images gallery

基本描述

别名	氯三甲基锡烷
英文别名	AKOS015840043 \| trimethyl tinchloride \| NCIOpen2_001307 \| TRIMETHYLTIN(IV) CHLIRIDE \| trimethyltinchloride \| EINECS 213-917-8 \| NSC-12088 \| Me3SnCl \| UNII-9E3BCA3684 \| WLN: G-SN-1&1&1 \| (CH3)3SnCl \| Chlorotrimethyltin \| MFCD00000520 \| Trimethyltin chlorid
规格或纯度	≥97%
英文名称	Trimethyltin chloride
应用	三甲基氯化锡是一种有机锡试剂，广泛用于将三甲基甲锡烷基转移至基质上以合成各种有机锡烷。衍生自该试剂的三甲基甲锡烷基化合物被广泛用于钯催化的Stille偶联反应
储存温度	2-8°C储存,充氩
运输条件	冰袋运输
产品介绍	An organometallic compound for proteomics research An organometallic compound for proteomics research

名称和识别符

EC号	213-917-8
分子类型	小分子
IUPAC Name	chloro(trimethyl)stannane
INCHI	InChI=1S/3CH3.ClH.Sn/h3*1H3;1H;/q;;;;+1/p-1
InChi Key	KWTSZCJMWHGPOS-UHFFFAOYSA-M
Canonical SMILES	C[Sn](C)(C)Cl
Isomeric SMILES	C[Sn](C)(C)Cl
WGK Germany	2
RTECS	WH6850000
PubChem CID	14016
UN Number	3146
Packing Group	I
分子量	199.27
Beilstein号	3535111

化学和物理性质

溶解性	Soluble in water, chloroform and organic solvents.
密度	0.988
敏感性	对湿度敏感
闪点(℉)	-9.4 °
闪点(℃)	-23 °C
沸点	148°C
熔点	37-39°C
分子量	199.270 g/mol
XLogP3
氢键供体数Hydrogen Bond Donor Count	0
氢键受体数Hydrogen Bond Acceptor Count	0
可旋转键计数Rotatable Bond Count	0
精确质量Exact Mass	199.941 Da
单同位素质量Monoisotopic Mass	199.941 Da
拓扑极表面积Topological Polar Surface Area	0.000 Å²
重原子数Heavy Atom Count	5
形式电荷Formal Charge	0
复杂度Complexity	28.400
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	0
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

象形图	GHS06, GHS09
信号词	Danger
危险声明	H400: 对水生生物有剧毒 H410: 对水生生物有剧毒并具有长期持续影响 H300: 吞咽致命 H310: 与皮肤接触致命 H330: 吸入致命
预防措施声明	P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P284: 如果通风不良，请佩戴呼吸防护装置。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P403+P233: 存放在通风良好的地方。保持容器密闭。 P391: 收集溢出物 P330: 漱口 P262: 不要进入眼睛、皮肤或衣服。 P320: 迫切需要特殊治疗（请参阅此标签上的...）。 P361+P364: 立即脱掉所有沾染的衣服，清洗后方可重新使用。 P301+P316: 如果吞咽：立即寻求紧急医疗救助。 P316: 立即寻求紧急医疗救助。
WGK Germany	2
RTECS	WH6850000
Class	6.1
个人防护装备	Eyeshields,Faceshields,full-face particle respirator type N100 (US),Gloves,respirator cartridge type N100 (US),type P1 (EN143) respirator filter,type P3 (EN 143) respirator cartridges

SDS英文版

技术规格说明书

Purity(GC)	97-100（%）
Melting point	38-42（℃）
Appearance（T113979)	White Solid
Infrared spectrum	Conforms to Structure
Solubility in Toluene	almost transparency

技术规格说明书

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到6个结果

批号(Lot Number)	证书类型	日期	货号
C2520690	分析证书	25-03-08	T113979
C2520691	分析证书	25-03-08	T113979
C2526834	分析证书	25-03-08	T113979
G2219958	分析证书	22-06-21	T113979
G2219959	分析证书	22-06-21	T113979
G2219960	分析证书	22-06-21	T113979

可替换产品

此产品的引用文献

如何在您的发表作品中引用阿拉丁的产品和网站?

1. Yuting Gao, Wenli Liao, Ruyi Zhang, Yining Lei, Tao Chen, Lingling Wu, Manqin Li, Xinran Liu, Fei Cai. (2023) PK2/PKRs pathway is involved in the protective effect of artemisinin against trimethyltin chloride-induced hippocampal injury. TOXICOLOGY, 486 (153432). [PMID:36696940] [10.1016/j.tox.2023.153432]
2. Hanning Zhang, Shuangyu Tian, Mu Li, Jinhai Xie, HongLian Dai, Liuyong Hu, Lesan Yan. (2022) Novel Donor–Acceptor Conjugated Polymer-Based Nanomicelles for Photothermal Therapy in the NIR Window. BIOMACROMOLECULES, 23 (8): (3243–3256). [PMID:35862795] [10.1021/acs.biomac.2c00330]
3. Rui Li, Haoran Xu, Yuhang Zhang, Lijing Chang, Yang Ma, Yanjun Hou, Shoulei Miao, Cheng Wang. (2021) Electrochromic properties of pyrene conductive polymers modified by chemical polymerization. RSC Advances, 11 (62): (39291-39305). [PMID:35492490] [10.1039/D1RA07977H]
4. Zhen Liu, Le Wang, Weiwei Bian, Min Zhang, Jinhua Zhan. (2017) Porous silver coating fiber for rapidly screening organotin compounds by solid phase microextraction coupled with surface enhanced Raman spectroscopy. RSC Advances, 7 (6): (3117-3124). [10.1039/C6RA25491H]
5. Jiamiao Wang, Jurong Lv, Zheyu Shen, Yan Liu, Xia Gao, Qiang Chen, Pei Liang. (2025) Development of rapid and data-driven detection methods for organotin compounds from microplastics: Integrating theoretical and experimental Raman and SERS database. MICROCHEMICAL JOURNAL, 209 (112836). [10.1016/j.microc.2025.112836]
6. Xiaotong Ni, Haozheng Hong, Haotian Xu, Meng Qi, Shiwen Xu. (2024) Exposure to Trimethyltin Chloride Induces Pyroptosis and Immune Dysfunction in Grass Carp CIK Cells by Activating the NF-κB Pathway Through Oxidative Stress. ENVIRONMENTAL TOXICOLOGY, [PMID:39004893] [10.1002/tox.24371]
7. Songlin Wang, Chi Chen, Peng Yang, Yu Guo, Bingxing Wang, Hongying Niu, Qiying Zhang, Jianji Wang. (2024) Facile One-Pot Preparation of Organotin-Oxometalate Polymers for Efficient Synthesis of Dimethyl Carbonate from CO2. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 63 (23): (10151-10161). [10.1021/acs.iecr.4c00937]
8. Jun Li, Meixin Hu, Yingying Liu, Rongrong Lu, Weijun Feng. (2024) Lead exposure leads to premature neural differentiation via inhibiting Wnt signaling. ENVIRONMENTAL POLLUTION, 363 (125232). [PMID:39489322] [10.1016/j.envpol.2024.125232]
9. Xinzhang Chen, Xu Lin. (2024) Sodium selenite antagonizes trimethyl tin-induced chicken hepatotoxic hepatitis through the RNS/NF-κB/NLRP3 pathway. POULTRY SCIENCE, (104449). [PMID:39577171] [10.1016/j.psj.2024.104449]

参考文献

1. Katharina Krüger,Victoria Diepgrond,Maria Ahnefeld,Christina Wackerbeck,Michael Madeja,Norbert Binding,Ulrich Musshoff. (2005-01-19) Blockade of glutamatergic and GABAergic receptor channels by trimethyltin chloride.. British journal of pharmacology, 144 ((2)): (283-292). [PMID:15655511]
2. Ana-Maria Florea,Elke Dopp,Dietrich Büsselberg. (2005-01-27) Elevated Ca2+(i) transients induced by trimethyltin chloride in HeLa cells: types and levels of response.. Cell calcium, 37 ((3)): (251-258). [PMID:15670872]
3. Bethany A Buck-Koehntop,Alessandro Mascioni,Jarrod J Buffy,Gianluigi Veglia. (2005-10-26) Structure, dynamics, and membrane topology of stannin: a mediator of neuronal cell apoptosis induced by trimethyltin chloride.. Journal of molecular biology, 354 ((3)): (652-665). [PMID:16246365]
4. Kiyokazu Ogita,Norito Nishiyama,Chie Sugiyama,Kei Higuchi,Masanori Yoneyama,Yukio Yoneda. (2005-11-08) Regeneration of granule neurons after lesioning of hippocampal dentate gyrus: evaluation using adult mice treated with trimethyltin chloride as a model.. Journal of neuroscience research, 82 ((5)): (609-621). [PMID:16273549]
5. Ge Zhang,Qiu-ping Xu,Hai-ying Huang. (2006-06-02) [Acute trimethyltin chloride poisoning in 45 patients].. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 24 ((5)): (308-309). [PMID:16737604]
6. Erwin van Vliet,Luc Stoppini,Maurizio Balestrino,Chantra Eskes,Claudius Griesinger,Tomasz Sobanski,Maurice Whelan,Thomas Hartung,Sandra Coecke. (2007-08-19) Electrophysiological recording of re-aggregating brain cell cultures on multi-electrode arrays to detect acute neurotoxic effects.. Neurotoxicology, 28 ((6)): (1136-1146). [PMID:17692379]
7. Koichi Kawada,Masanori Yoneyama,Reiko Nagashima,Kiyokazu Ogita. (2008-01-10) In vivo acute treatment with trimethyltin chloride causes neuronal degeneration in the murine olfactory bulb and anterior olfactory nucleus by different cascades in each region.. Journal of neuroscience research, 86 ((7)): (1635-1646). [PMID:18183623]
8. Mengmeng Wang,Bowen Li,Chonggang Wang,Yixin Chen,Zhenghong Zuo. (2008-04-16) The concentration-dependent induction of cell death by trimethyltin chloride in rat liver epithelial IAR20 cells.. Toxicology in vitro : an international journal published in association with BIBRA, 22 ((5)): (1136-1142). [PMID:18411021]
9. Guangshu Zhai,Jingfu Liu,Bin He,Jianbin Zhang,Qunfang Zhou,Guibin Jiang. (2008-04-25) Ultraviolet degradation of methyltins: elucidating the mechanism by identification of a detected new intermediary product and investigating the kinetics at various environmental conditions.. Chemosphere, 72 ((3)): (389-399). [PMID:18433831]
10. Reiko Nagashima,Chie Sugiyama,Yuka Gotoh,Masanori Yoneyama,Nobuyuki Kuramoto,Takahiro Taira,Hiroyoshi Ariga,Kiyokazu Ogita. (2008-06-24) Altered expression of DJ-1 in the hippocampal cells following in vivo and in vitro neuronal damage induced by trimethyltin.. Neuroscience letters, 440 ((3)): (232-236). [PMID:18572315]
11. Jian-Hua Wei,Xian-Min Ge,Jia-le Huang. (2008-09-06) [Four patients with acute trimethyltin chloride poisoning induced in waste plastics manufacturing].. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 26 ((6)): (378-378). [PMID:18771630]
12. Ya-ling Qian,Hong-fang Tang,Yan-hua Wang,Zheng Ruan,Hao Wu,Cheng-min Xu,Xing Zhang. (2009-04-11) [Biological monitoring of workers exposed to trimethyltin chloride].. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 26 ((8)): (461-464). [PMID:19358754]
13. Helena T Hogberg,Agnieszka Kinsner-Ovaskainen,Sandra Coecke,Thomas Hartung,Anna K Bal-Price. (2009-08-05) mRNA expression is a relevant tool to identify developmental neurotoxicants using an in vitro approach.. Toxicological sciences : an official journal of the Society of Toxicology, 113 ((1)): (95-115). [PMID:19651682]
14. Flaviana T Vieira,Geraldo M de Lima,José R da S Maia,Nivaldo L Speziali,José D Ardisson,Leonardo Rodrigues,Ary Correa,Oscar B Romero. (2009-12-05) Synthesis, characterization and biocidal activity of new organotin complexes of 2-(3-oxocyclohex-1-enyl)benzoic acid.. European journal of medicinal chemistry, 45 ((3)): (883-889). [PMID:19959261]
15. Xiaojiang Tang,Xiaojun Yang,Guanchao Lai,Jinhui Guo,Lihua Xia,Banghua Wu,Yuxuan Xie,Ming Huang,Jiabin Chen,Xiaolin Ruan,Gang Sui,Yichen Ge,Wulin Zuo,Na Zhao,Guanghua Zhu,Jinxin Zhang,Laiyu Li,Wenliang Zhou. (2010-03-10) Mechanism underlying hypokalemia induced by trimethyltin chloride: Inhibition of H+/K+-ATPase in renal intercalated cells.. Toxicology, 271 ((1-2)): (45-50). [PMID:20211677]
16. Guo-hua Zhou. (2011-01-19) [Emergency treatment and nursing for acute trimethyltin chloride poisoning].. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 28 ((11)): (879-880). [PMID:21241593]
17. Na Zhao,Gang Sui,Nan-Chun Li,Xin Wu,Zi Yang,Guan-Chao Lai,Yan Yang,Zhong-Ning Lin,Xiao-Jiang Tang. (2011-09-29) [Study on activities and protein and gene expression of renal H(+)-K(+)-ATPase in rats subchronic exposed to trimethyltin chloride].. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 29 ((4)): (299-302). [PMID:21941786]
18. Nguyen Quynh Huong,Yukary Nakamura,Nobuyuki Kuramoto,Masanori Yoneyama,Reiko Nagashima,Tatsuo Shiba,Taro Yamaguchi,Shigeru Hasebe,Kiyokazu Ogita. (2011-12-02) Indomethacin ameliorates trimethyltin-induced neuronal damage in vivo by attenuating oxidative stress in the dentate gyrus of mice.. Biological & pharmaceutical bulletin, 34 ((12)): (1856-1863). [PMID:22130242]
19. Yun Xiao,Li-jin Zhu,Li Jv,Ya-ling Qian,Xing Zhang. (2012-02-24) [The protein expression profiles induced by trimethyltin chloride in Vero cells].. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 29 ((10)): (721-725). [PMID:22357484]
20. Alessandra Tamburella,Vincenzo Micale,Carmen Mazzola,Salvatore Salomone,Filippo Drago. (2012-03-20) The selective norepinephrine reuptake inhibitor atomoxetine counteracts behavioral impairments in trimethyltin-intoxicated rats.. European journal of pharmacology, 683 ((1-3)): (148-154). [PMID:22426162]
21. Da Jung Kim,Yong Sik Kim. (2015-07-30) Trimethyltin-Induced Microglial Activation via NADPH Oxidase and MAPKs Pathway in BV-2 Microglial Cells.. Mediators of inflammation, 2015 (729509-729509). [PMID:26221064]
22. Kelly Peeters,Gaëtane Lespes,Radmila Milačič,Janez Ščančar. (2015-08-19) Adsorption and degradation processes of tributyltin and trimethyltin in landfill leachates treated with iron nanoparticles.. Environmental research, 142 (511-521). [PMID:26280471]
23. Yu Xi,Mengyu Liu,Shuzhen Xu,Huihui Hong,Mengyan Chen,Li Tian,Jia Xie,Ping Deng,Chao Zhou,Lei Zhang,Mindi He,Chunhai Chen,Yonghui Lu,Russel J Reiter,Zhengping Yu,Huifeng Pi,Zhou Zhou. (2019-07-25) Inhibition of SERPINA3N-dependent neuroinflammation is essential for melatonin to ameliorate trimethyltin chloride-induced neurotoxicity.. Journal of pineal research, 67 ((3)): (e12596-e12596). [PMID:31332839]
24. Ya-ling Qian,Hong-fang Tang,Zheng Ruan. (2009-04-11) [Survey on occupational trimethyltin chloride poisoning in enterprises using methyltin mercaptide].. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 26 ((8)): (472-473). [PMID:19358758]
25. Jiali Cai,Mengmeng Wang,Bowen Li,Chonggang Wang,Yixin Chen,Zhenghong Zuo. (2009-08-07) Apoptotic and necrotic action mechanisms of trimethyltin in human hepatoma G2 (HepG2) cells.. Chemical research in toxicology, 22 ((9)): (1582-1587). [PMID:19655806]
26. Yuting Gao, Wenli Liao, Ruyi Zhang, Yining Lei, Tao Chen, Lingling Wu, Manqin Li, Xinran Liu, Fei Cai. (2023) PK2/PKRs pathway is involved in the protective effect of artemisinin against trimethyltin chloride-induced hippocampal injury. TOXICOLOGY, 486 (153432). [PMID:36696940] [10.1016/j.tox.2023.153432]
27. Hanning Zhang, Shuangyu Tian, Mu Li, Jinhai Xie, HongLian Dai, Liuyong Hu, Lesan Yan. (2022) Novel Donor–Acceptor Conjugated Polymer-Based Nanomicelles for Photothermal Therapy in the NIR Window. BIOMACROMOLECULES, 23 (8): (3243–3256). [PMID:35862795] [10.1021/acs.biomac.2c00330]
28. Rui Li, Haoran Xu, Yuhang Zhang, Lijing Chang, Yang Ma, Yanjun Hou, Shoulei Miao, Cheng Wang. (2021) Electrochromic properties of pyrene conductive polymers modified by chemical polymerization. RSC Advances, 11 (62): (39291-39305). [PMID:35492490] [10.1039/D1RA07977H]
29. Zhen Liu, Le Wang, Weiwei Bian, Min Zhang, Jinhua Zhan. (2017) Porous silver coating fiber for rapidly screening organotin compounds by solid phase microextraction coupled with surface enhanced Raman spectroscopy. RSC Advances, 7 (6): (3117-3124). [10.1039/C6RA25491H]
30. Jiamiao Wang, Jurong Lv, Zheyu Shen, Yan Liu, Xia Gao, Qiang Chen, Pei Liang. (2025) Development of rapid and data-driven detection methods for organotin compounds from microplastics: Integrating theoretical and experimental Raman and SERS database. MICROCHEMICAL JOURNAL, 209 (112836). [10.1016/j.microc.2025.112836]
31. Xiaotong Ni, Haozheng Hong, Haotian Xu, Meng Qi, Shiwen Xu. (2024) Exposure to Trimethyltin Chloride Induces Pyroptosis and Immune Dysfunction in Grass Carp CIK Cells by Activating the NF-κB Pathway Through Oxidative Stress. ENVIRONMENTAL TOXICOLOGY, [PMID:39004893] [10.1002/tox.24371]
32. Songlin Wang, Chi Chen, Peng Yang, Yu Guo, Bingxing Wang, Hongying Niu, Qiying Zhang, Jianji Wang. (2024) Facile One-Pot Preparation of Organotin-Oxometalate Polymers for Efficient Synthesis of Dimethyl Carbonate from CO2. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 63 (23): (10151-10161). [10.1021/acs.iecr.4c00937]
33. Jun Li, Meixin Hu, Yingying Liu, Rongrong Lu, Weijun Feng. (2024) Lead exposure leads to premature neural differentiation via inhibiting Wnt signaling. ENVIRONMENTAL POLLUTION, 363 (125232). [PMID:39489322] [10.1016/j.envpol.2024.125232]
34. Xinzhang Chen, Xu Lin. (2024) Sodium selenite antagonizes trimethyl tin-induced chicken hepatotoxic hepatitis through the RNS/NF-κB/NLRP3 pathway. POULTRY SCIENCE, (104449). [PMID:39577171] [10.1016/j.psj.2024.104449]

溶液计算器

摩尔浓度计算器

计算溶液所需的质量、体积或浓度。

质量

浓度

体积

分子量

g/mol

稀释计算器

计算配制储备溶液所需的稀释度。

浓度1（C1）

体积 1 (V1)

浓度 2 (C2)

体积 2 (V2)

复溶计算器

复溶计算器允许您快速计算试剂的体积，以复溶小瓶。只需输入试剂的质量和目标浓度，计算器将确定其余部分。

体积（添加到小瓶中）

质量（小瓶）

所需的复溶浓度