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提供 ≥99% 纯度,适用于对基线干扰要求严格的色谱和分析工作流程。
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Tat-braftide is a peptide inhibitor designed to block the dimerization of BRAF , thereby inhibiting its kinase activity. The destruction of BRAF dimer by Tat-braftide makes BRAF protein more susceptible to proteasome degradation, directly inhibits the activity of BRAF kinase, and reduces the activation of MAPK signaling pathway. Tat-braftide can be used for the role of RAF kinase in MAPK signaling pathway and for the study of BRAF mutant cancers.