转铁蛋白 (部分铁饱和) 来源于人血浆

Name: 转铁蛋白 (部分铁饱和) 来源于人血浆
SKU: T754984
Availability: InStock

CAS: 11096-37-0 货号: T754984

19篇引用文献 COA

有货

级别和纯度: BioReagent ? 天然 ? 组织培养级 ? ≥98%(SDS-PAGE) 铁含量：300-600μg/g; 冻干前浓度：见COA

Accession #

P02787

规格

库存

价格

数量

25mg

T754984-25mg

现货

¥899.90

100mg

T754984-100mg

现货

¥1,699.90

500mg

T754984-500mg

期货

¥5,799.90

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概述规格储存与运输图片技术文档高级数据产品属性质检证书（CoA,COO,BSE/TSE 和分析图谱) 此产品的引用文献技术文档和文章溶液计算器常见问题

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为什么选择此级别

BioReagent,天然,组织培养级提供 ≥98%(SDS-PAGE) 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。

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储存与运输

-20°C储存,避免反复冻融。超低温运输。请查阅批次 COA 获取详细规格。

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质量文档

SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。

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文献证明

在色谱分析、有机合成和交叉偶联反应领域已被 19 篇同行评审文献引用。

概述

Transferrin is a glycoprotein with a branched carbohydrate chain, having two sites for ferric ion binding in its polypeptide chain.

Application

Transferrin human has been used:

to incubate human proximal tubule cells (HKC) - 8 cells along with IgG for the examination of albumin specificity;
as a supplement in serum-containing/devoid medium for human thyroid cell culture;
as a target glycoprotein to develop an in-gel hydrazinolysis method.

Biochem/physiol Actions

Transferrin mediates iron transportation from plasma to cells. The iron-bound transferrin are of three forms: monoferric A/B transferrin and diferric transferrin. The transferrin binds to specific cell surface receptors and are internalized by endocytosis. Once inside, the iron is released into the cells and the iron-free transferrin, also referred to as apotransferrin, is exocytosed outside the cell without being degraded. Transferrin is known to deliver iron to cells in a physiologically safe and effective form.

Preparation Note

Heat treated at 60°C for 10 hours.

Other Notes

Partially iron-saturated

Iron Content: 300-600 ug Fe/g protein

Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests.

规格

产品名称

转铁蛋白 (部分铁饱和) 来源于人血浆

别名

转铁蛋白,部分饱和

英文别名

Siderophilin, partially saturated | Serotransferrin | TF | TFQTL1 | PRO1557 | PRO2086 | HEL-S-71p

规格或纯度

BioReagent, 天然, 组织培养级, ≥98%(SDS-PAGE), 铁含量：300-600μg/g; 冻干前浓度：见COA

生化机理

Transferrins are iron binding transport proteins which can bind two Fe3+ ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. (Microbial infection) Serves as an iron source for Neisseria species, which capture the protein and extract its iron for their own use. (Microbial infection) Serves as an iron source for parasite T.brucei (strain 427), which capture TF via its own transferrin receptor ESAG6:ESAG7 and extract its iron for its own use.

种属

人(Human)

来源

天然

预测分子量

80 kDa

CAS编号和信息

11096-37-0

分子类型

蛋白质

产品线

生物产品

储存与运输

物理形态

冻干(Lyophilized)

储存缓冲液

Lyophilized from sterile de-ionized water, pH 7.0-7.5.

浓度

铁含量：300-600μg/g; 冻干前浓度：见COA

复溶

After centrifugation, we suggest addition of de-ionized H2O to the original volume (See COA), followed by gentle mixingto ensure adequate homogenization. If further dilution is required, please use the lyophilization buffer.

储存条件

-20°C储存,避免反复冻融

运输条件

超低温运输

稳定性与储存

长期储存-20℃（＞1年）；复溶后建议分装，避免反复冻融。

图片

SDS-PAGE: Transferrin (Partially Iron Saturated) from Human Plasma (T754984)

Transferrin (Partially Iron Saturated) from Human Plasma (T754984) - SDS-PAGE

2 μg/lane of Transferrin (Partially Iron Saturated) from Human Plasma was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 76 kDa under reducing condition and 65 kDa under non-reducing condition.