哌嗪类

描述:

含有哌嗪环的化合物，该环为饱和脂肪族六元杂环，在1位和4位各含一个氮原子，以及四个碳原子。

上级分类:

有机化合物 ⮕ 有机杂环化合物 ⮕ 二嗪烷 ⮕ 哌嗪类

产品列表

收藏夹比较

DS-7423
化合物 CID: 45378170

Moligand™ ?

期货货号: D609983

查看产品
价格与包装

技术标识符

IUPAC名称

1-[(2R)-4-[2-(2-aminopyrimidin-5-yl)-6-morpholin-4-yl-9-(2,2,2-trifluoroethyl)purin-8-yl]-2-methylpiperazin-1-yl]ethanone

SMILES

C[C@@H]1CN(CCN1C(=O)C)C2=NC3=C(N2CC(F)(F)F)N=C(N=C3N4CCOCC4)C5=CN=C(N=C5)N

InChIKey

SOJJMSYMCLIQCZ-CYBMUJFWSA-N

InChI

1S/C22H27F3N10O2/c1-13-11-33(3-4-34(13)14(2)36)21-29-16-18(32-5-7-37-8-6-32)30-17(15-9-27-20(26)28-10-15)31-19(16)35(21)12-22(23,24)25/h9-10,13H,3-8,11-12H2,1-2H3,(H2,26,27,28)/t13-/m1/s1

关联靶标

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, Serine/threonine-protein kinase mTOR
收藏夹比较

EGIS-7625
化合物 CID: 9930789

Moligand™ ?

期货货号: E610082

查看产品
价格与包装

技术标识符

IUPAC名称

2-methyl-4-nitro-5-[4-(phenylmethyl)piperazin-1-yl]aniline

SMILES

Nc1cc(N2CCN(CC2)Cc2ccccc2)c(cc1C)[N+](=O)[O-]

InChIKey

ZEFXWOMFCPRXJW-UHFFFAOYSA-N

InChI

1S/C18H22N4O2/c1-14-11-18(22(23)24)17(12-16(14)19)21-9-7-20(8-10-21)13-15-5-3-2-4-6-15/h2-6,11-12H,7-10,13,19H2,1H3

关联靶标

5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2C, 5-hydroxytryptamine receptor 2B
收藏夹比较

CPPZ
化合物 CID: 24763119

Moligand™ ?

期货货号: C609588

查看产品
价格与包装

技术标识符

IUPAC名称

1-[4-(2-chloro-4-fluorophenyl)piperazin-1-yl]-2-(pyridin-4-ylmethoxy)ethanone

SMILES

Fc1ccc(c(c1)Cl)N1CCN(CC1)C(=O)COCc1ccncc1

InChIKey

XNOMHUDLVRWWLV-UHFFFAOYSA-N

InChI

1S/C18H19ClFN3O2/c19-16-11-15(20)1-2-17(16)22-7-9-23(10-8-22)18(24)13-25-12-14-3-5-21-6-4-14/h1-6,11H,7-10,12-13H2

关联靶标

Metabotropic glutamate receptor 5
收藏夹比较

CP-10
化合物 CID: 138911323

Moligand™ ?

期货货号: C609561

查看产品
价格与包装

技术标识符

SMILES

Cc1c(c(=O)n(c2nc(ncc12)Nc1ncc(cc1)N1CCN(CC1)Cc1cn(nn1)CCOCCNc1cccc2c1C(=O)N(C2=O)C1CCC(=O)NC1=O)C1CCCC1)C=O

InChIKey

MZTSDEMVUMXQFP-UHFFFAOYSA-N

InChI

1S/C43H47N13O7/c1-26-31-22-46-43(49-38(31)55(28-5-2-3-6-28)41(61)32(26)25-57)47-35-11-9-29(21-45-35)53-16-14-52(15-17-53)23-27-24-54(51-50-27)18-20-63-19-13-44-33-8-4-7-30-37(33)42(62)56(40(30)60)34-1显示更多

关联靶标

Cyclin-dependent kinase 4, Cyclin-dependent kinase 6
收藏夹比较

CP-293019
化合物 CID: 9820261

Moligand™ ?

期货货号: C609566

查看产品
价格与包装

技术标识符

IUPAC名称

(7R,9aS)-7-[(4-fluorophenoxy)methyl]-2-(5-fluoropyrimidin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine

SMILES

Fc1ccc(cc1)OC[C@@H]1CC[C@@H]2N(C1)CCN(C2)c1ncc(cn1)F

InChIKey

QXWNESOGWFJDFR-PBHICJAKSA-N

InChI

1S/C19H22F2N4O/c20-15-2-5-18(6-3-15)26-13-14-1-4-17-12-25(8-7-24(17)11-14)19-22-9-16(21)10-23-19/h2-3,5-6,9-10,14,17H,1,4,7-8,11-13H2/t14-,17+/m1/s1

关联靶标

D(4) dopamine receptor
收藏夹比较

BSJ-04-132
化合物 CID: 139593562

Moligand™ ?

期货货号: B608234

查看产品
价格与包装

技术标识符

IUPAC名称

7-Cyclopentyl-2-[[5-[4-[4-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl]oxy]acetamido]butyl]piperazin-1-yl]pyridin-2-yl]amino]-N,N-dimethyl-7H-pyrrolo[2,3d]pyrimidine-6-carboxamide

SMILES

O=C(COc1cccc2c1C(=O)N(C2=O)C1CCC(=O)NC1=O)NCCCCN1CCN(CC1)c1ccc(nc1)Nc1ncc2c(n1)n(C1CCCC1)c(c2)C(=O)N(C)C

InChIKey

GWLSXEHHNOBFOI-UHFFFAOYSA-N

InChI

1S/C42H49N11O7/c1-49(2)40(58)31-22-26-23-45-42(48-37(26)52(31)27-8-3-4-9-27)46-33-14-12-28(24-44-33)51-20-18-50(19-21-51)17-6-5-16-43-35(55)25-60-32-11-7-10-29-36(32)41(59)53(39(29)57)30-13-15-34(54)4显示更多

关联靶标

Cyclin-dependent kinase 4, Cyclin-dependent kinase 6
收藏夹比较

BMY-14802
CAS: 105565-56-8 EC号: 110-723-4 化合物 CID: 108046 分子式: C₁₈H₂₂F₂N₄O 分子量: 348.39

Moligand™ ?

期货货号: B608167

查看产品
价格与包装

技术标识符

IUPAC名称

1-(4-fluorophenyl)-4-[4-(5-fluoropyrimidin-2-yl)piperazin-1-yl]butan-1-ol

SMILES

C1CN(CCN1CCCC(C2=CC=C(C=C2)F)O)C3=NC=C(C=N3)F

InChIKey

ZXUYYZPJUGQHLQ-UHFFFAOYSA-N

InChI

1S/C18H22F2N4O/c19-15-5-3-14(4-6-15)17(25)2-1-7-23-8-10-24(11-9-23)18-21-12-16(20)13-22-18/h3-6,12-13,17,25H,1-2,7-11H2

关联靶标

Sigma non-opioid intracellular receptor 1, 5-hydroxytryptamine receptor 1A
收藏夹比较

BMY-7378
CAS: 21102-94-3 化合物 CID: 2419 分子式: C22H33Cl2N3O3 分子量: 458.43

Moligand™ ?

期货货号: B608170

查看产品
价格与包装

技术标识符

IUPAC名称

8-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-8-azaspiro[4.5]decane-7,9-dione

SMILES

COC1=CC=CC=C1N2CCN(CC2)CCN3C(=O)CC4(CCCC4)CC3=O

InChIKey

AYYCFGDXLUPJAQ-UHFFFAOYSA-N

InChI

1S/C22H31N3O3/c1-28-19-7-3-2-6-18(19)24-13-10-23(11-14-24)12-15-25-20(26)16-22(17-21(25)27)8-4-5-9-22/h2-3,6-7H,4-5,8-17H2,1H3

关联靶标

D(2) dopamine receptor, Alpha-1B adrenergic receptor, Alpha-1D adrenergic receptor, Alpha-1A adrenergic receptor, 5-hydroxytryptamine receptor 1A
收藏夹比较

BPKDi
CAS: 1201673-28-0 化合物 CID: 46901383 分子式: C₂₁H₂₈N₆O 分子量: 380.49

Moligand™ ? ≥95%

有现货货号: B608197

查看产品
价格与包装

技术标识符

IUPAC名称

2-[2-(cyclohexylamino)pyridin-4-yl]-6-piperazin-1-ylpyridine-4-carboxamide

SMILES

C1CCC(CC1)NC2=NC=CC(=C2)C3=NC(=CC(=C3)C(=O)N)N4CCNCC4

InChIKey

XNWDRALEEPGBHB-UHFFFAOYSA-N

InChI

1S/C21H28N6O/c22-21(28)16-12-18(26-20(14-16)27-10-8-23-9-11-27)15-6-7-24-19(13-15)25-17-4-2-1-3-5-17/h6-7,12-14,17,23H,1-5,8-11H2,(H2,22,28)(H,24,25)

关联靶标

Serine/threonine-protein kinase D2, Serine/threonine-protein kinase D1, Serine/threonine-protein kinase D3
收藏夹比较

AZD6703
CAS: 1083381-65-0 化合物 CID: 11373432

Moligand™ ?

期货货号: A607882

查看产品
价格与包装

技术标识符

IUPAC名称

N-cyclopropyl-4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxoquinazolin-3-yl]benzamide

SMILES

CN1CCN(CC1)c1ccc2c(c1)c(=O)n(cn2)c1cc(ccc1C)C(=O)NC1CC1

InChIKey

ZMAZXHICVRYLQN-UHFFFAOYSA-N

InChI

1S/C24H27N5O2/c1-16-3-4-17(23(30)26-18-5-6-18)13-22(16)29-15-25-21-8-7-19(14-20(21)24(29)31)28-11-9-27(2)10-12-28/h3-4,7-8,13-15,18H,5-6,9-12H2,1-2H3,(H,26,30)

关联靶标

Mitogen-activated protein kinase 14
收藏夹比较

AZD9574
化合物 CID: 162524593

Moligand™ ?

期货货号: A607896

查看产品
价格与包装

技术标识符

IUPAC名称

6-fluoro-5-[4-[(5-fluoro-2-methyl-3-oxo-4H-quinoxalin-6-yl)methyl]piperazin-1-yl]-N-methylpyridine-2-carboxamide

SMILES

CNC(=O)c1nc(F)c(cc1)N1CCN(Cc2c(F)c3c(cc2)nc(C)c(=O)[nH]3)CC1

InChIKey

WXRCLFFPZXJCLS-UHFFFAOYSA-N

InChI

1S/C21H22F2N6O2/c1-12-20(30)27-18-14(25-12)4-3-13(17(18)22)11-28-7-9-29(10-8-28)16-6-5-15(21(31)24-2)26-19(16)23/h3-6H,7-11H2,1-2H3,(H,24,31)(H,27,30)

关联靶标

Poly [ADP-ribose] polymerase 1, Poly [ADP-ribose] polymerase 2
收藏夹比较

BAY1238097
CAS: 1564268-08-1 化合物 CID: 118237331

Moligand™ ?

期货货号: B607937

查看产品
价格与包装

技术标识符

IUPAC名称

(4S)-7,8-dimethoxy-N,4-dimethyl-1-[4-(4-methylpiperazin-1-yl)phenyl]-4,5-dihydro-2,3-benzodiazepine-3-carboxamide

SMILES

CC1CC2=CC(=C(C=C2C(=NN1C(=O)NC)C3=CC=C(C=C3)N4CCN(CC4)C)OC)OC

InChIKey

CJIPEACKIJJYED-KRWDZBQOSA-N

InChI

1S/C25H33N5O3/c1-17-14-19-15-22(32-4)23(33-5)16-21(19)24(27-30(17)25(31)26-2)18-6-8-20(9-7-18)29-12-10-28(3)11-13-29/h6-9,15-17H,10-14H2,1-5H3,(H,26,31)/t17-/m0/s1

关联靶标

Bromodomain-containing protein 4