基本描述

别名	D-麸氨酸 \| (R)-2-氨基戊二酸 \| R-(-)-1-氨基丙烷-1,3-二羧酸
英文别名	(r)-1-aminopropane-1,3-dicarboxylic acid \| (2R)-2-aminopentanedioate \| SR-01000597732 \| CHEBI:53375 \| GLUTAMIC ACID D-FORM [MI] \| C00217 \| D-Glutaminic acid \| PDSP2_001470 \| D-2-Aminoglutaric acid \| delta-Glutaminate \| D-Glutamic acid, >=99% (TLC) \| DB025
规格或纯度	Moligand™, ≥98%
英文名称	D-Glutamic acid
生化机理	作用于NMDA受体的兴奋性氨基酸；活性比L-异构体低。
应用	D-谷氨酸适用于GR酶（谷氨酸消旋酶）及其抑制剂的结构亲和关系（SAR）研究。
运输条件	常规运输
产品介绍	谷氨酸的非天然异构体。水中溶解度:7 g/L (20°C)，实际上不溶于有机溶剂。D-谷氨酸适用于GR酶（谷氨酸消旋酶）及其抑制剂的结构亲和关系（SAR）研究。 D-谷氨酸是细菌肽聚糖结构的必需成分。可通过D-谷氨酸添加酶（murD）将其加入UDP-N-乙酰胞壁酰-L-丙氨酸（UDP-MurNAc-L-丙氨酸）中。然后将其掺入肽聚糖前体中。肽聚糖构成革兰氏阳性和阴性细菌的细胞壁。通过谷氨酸消旋酶（GR）将L-谷氨酸转化为D-谷氨酸是肽聚糖合成中必不可少的步骤。 D-Glutamic acid is an essential constituent of the bacterial peptidoglycan structure. It is added to UDP-N-acetylmuramyl-L-alanine (UDP-MurNAc-L-alanine) by the enzyme D-glutamic acid-adding enzyme (murD). This is, then, incorporated into the peptidoglycan precursor. Peptidoglycan makes up the cell walls of Gram-positive and -negative bacteria. The conversion of L-glutamate to D-glutamate by glutamate racemase (GR) enzyme is an essential step in the synthesis of peptidoglycan. application： D-Glutamic acid acts as a superior to alpha ketoglutarate. It helps in the growth of Lactobacillus arabinosus. It can inhibit the IgE binding to peanut allergens. It is widely used in pharmaceuticals and foods.

AI解读

关联靶点（人）

CA2 Tclin Carbonic anhydrase II (17698 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GRM3 Tchem Metabotropic glutamate receptor 3 (732 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CA1 Tclin Carbonic anhydrase I (13240 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GRM4 Tchem Metabotropic glutamate receptor 4 (2320 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GRM6 Tchem Metabotropic glutamate receptor 6 (361 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GRM1 Tchem Metabotropic glutamate receptor 1 (2309 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GRM5 Tchem Metabotropic glutamate receptor 5 (5733 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2D6 Tclin Cytochrome P450 2D6 (33882 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC1A3 Tchem Excitatory amino acid transporter 1 (586 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP1A2 Tchem Cytochrome P450 1A2 (26471 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2C9 Tchem Cytochrome P450 2C9 (32119 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2C19 Tchem Cytochrome P450 2C19 (29246 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP3A4 Tclin Cytochrome P450 3A4 (53859 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

THP-1 (11052 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 (22556 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

FTO Tchem Alpha-ketoglutarate-dependent dioxygenase FTO (473 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

关联靶点（其它种属）

Grm2 Metabotropic glutamate receptor 2 (1326 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Pkm Pyruvate kinase isozymes M1/M2 (66 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Grm7 Metabotropic glutamate receptor 7 (580 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

murI Glutamate racemase (2 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rattus norvegicus (775804 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

lef Anthrax lethal factor (7585 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ffp 4'-phosphopantetheinyl transferase ffp (24982 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Gria2 Glutamate receptor ionotropic, AMPA (2103 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Grik1 Glutamate receptor ionotropic, kainate (722 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Carbonic anhydrase-like protein, putative (25 活性数据)

点击查看此靶标相关信息

活性类型	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

名称和识别符

PubChem SID	488182816
EC号	230-000-8
分子类型	小分子
IUPAC Name	(2R)-2-aminopentanedioic acid
INCHI	InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m1/s1
InChi Key	WHUUTDBJXJRKMK-GSVOUGTGSA-N
Canonical SMILES	C(CC(=O)O)C(C(=O)O)N
Isomeric SMILES	C(CC(=O)O)[C@H](C(=O)O)N
WGK Germany	1
PubChem CID	23327
分子量	147.13
Beilstein号	1723800
Reaxy-Rn	1723800

化学和物理性质

溶解性	溶于水，微溶于乙醇，不溶于乙醚
比旋光度	-30.0 to -33.0 deg(C=5, HCl(1+5))
熔点	200-202°C
分子量	147.130 g/mol
XLogP3	-3.700
氢键供体数Hydrogen Bond Donor Count	3
氢键受体数Hydrogen Bond Acceptor Count	5
可旋转键计数Rotatable Bond Count	4
精确质量Exact Mass	147.053 Da
单同位素质量Monoisotopic Mass	147.053 Da
拓扑极表面积Topological Polar Surface Area	101.000 Å²
重原子数Heavy Atom Count	10
形式电荷Formal Charge	0
复杂度Complexity	145.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	1
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

WGK Germany	1
Reaxy-Rn	1723800
Merck Index	4469
个人防护装备	Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

技术规格说明书

Purity(NonaqueousTitration)	97.5-102.5（%）
Specific Rotation [a]20/D(c=5 in HCl(1+5)	-33--30（°）
Appearance（G100444)	White to Off-White Powder
Solubility in 0.5 M HCl，Colorless,Clear at 50 mg/ml	pass
Proton NMR spectrum	Conforms to structure

技术规格说明书

质检证书（CoA,COO,BSE/TSE 和分析图谱)

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找到27个结果

批号(Lot Number)	证书类型	日期	货号
L2031127	分析证书	24-10-14	G100444
I2411359	分析证书	24-09-02	G100444
I2411358	分析证书	24-09-02	G100444
I2411357	分析证书	24-09-02	G100444
I2411356	分析证书	24-09-02	G100444
I2411355	分析证书	24-09-02	G100444
E2411269	分析证书	24-03-21	G100444
G2321382	分析证书	23-06-30	G100444
G2321427	分析证书	23-06-30	G100444
G2321381	分析证书	23-06-30	G100444
G2321365	分析证书	23-06-30	G100444
G2321358	分析证书	23-06-30	G100444
G2321350	分析证书	23-06-30	G100444
G2321286	分析证书	23-06-30	G100444
B2309083	分析证书	22-07-04	G100444
J2222325	分析证书	22-07-04	G100444
J2222326	分析证书	22-07-04	G100444
J2222328	分析证书	22-07-04	G100444
J2222345	分析证书	22-07-04	G100444
J2222354	分析证书	22-07-04	G100444
J2222358	分析证书	22-07-04	G100444
D2319408	分析证书	22-07-04	G100444
F2218030	分析证书	22-06-22	G100444
E2223106	分析证书	22-02-26	G100444
E2223104	分析证书	22-02-26	G100444
E2223103	分析证书	22-02-26	G100444
E2223102	分析证书	22-02-26	G100444

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溶液计算器

摩尔浓度计算器

计算溶液所需的质量、体积或浓度。

质量

浓度

体积

分子量

g/mol

稀释计算器

计算配制储备溶液所需的稀释度。

浓度1（C1）

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浓度 2 (C2)

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复溶计算器

复溶计算器允许您快速计算试剂的体积，以复溶小瓶。只需输入试剂的质量和目标浓度，计算器将确定其余部分。

体积（添加到小瓶中）

质量（小瓶）

所需的复溶浓度

货号 (SKU)	包装规格	是否现货
G100444-5g	5g	现货
G100444-25g	25g	现货
G100444-50g	50g	现货
G100444-100g	100g	现货
G100444-250g	250g	现货
G100444-500g	500g	现货

D-谷氨酸

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库存信息

库存信息

库存信息

库存信息

库存信息

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质检证书（CoA,COO,BSE/TSE 和分析图谱)

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溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器

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