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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| P329494-1mg |
1mg |
期货  |
|
| 英文别名 | 200625-47-4|[(2S,3R,4R,6S)-6-[(2R,3S,6S)-6-[[(1S,4aS,12aR)-3-acetyl-4,4a,6,12a-tetrahydroxy-9-methoxy-11-methyl-2,5,7,10-tetraoxo-1,12-dihydrotetracen-1-yl]oxy]-2-methyloxan-3-yl]oxy-4-hydroxy-2,4-dimethyloxan-3-yl] 2-hydroxy-3,6-dimethylbenzoate|1,3,7,10 |
|---|---|
| 英文名称 | Polyketomycin |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 产品介绍 |
聚酮霉素是四环醌糖苷，具有由链霉菌产色链霉菌产生的抗菌，抗肿瘤和抗疟原性。被称为蒽环类抗生素，对革兰氏阳性多药菌株（包括耐甲氧西林的金黄色葡萄球菌（MRSA））具有细胞毒性和生长抑制能力。在实验中显示对多种癌细胞具有有效的抗肿瘤活性。 Polyketomycin is a tetracyclic quinone glycoside with antibacterial, antitumor, and antimalarial ativity produced by Streptomyces diastatochromogenes. Known as an anthracycline antibiotic displaying cytotoxic and growth inhibitory ability against Gram-positive multi drug strains including methicillin-resistant Staphylococcus aureus (MRSA). Shown in experiments to have potent antitumor activity against multiple cancer cell lines. |
| IUPAC Name | [(2S,3R,4R,6S)-6-[(2R,3S,6S)-6-[[(1S,4aS,12aR)-3-acetyl-4,4a,6,12a-tetrahydroxy-9-methoxy-11-methyl-2,5,7,10-tetraoxo-1,12-dihydrotetracen-1-yl]oxy]-2-methyloxan-3-yl]oxy-4-hydroxy-2,4-dimethyloxan-3-yl] 2-hydroxy-3,6-dimethylbenzoate |
|---|---|
| INCHI | InChI=1S/C44H48O18/c1-16-9-10-17(2)33(47)28(16)41(53)62-39-21(6)59-27(15-42(39,7)54)60-24-11-12-26(58-20(24)5)61-40-36(50)30(19(4)45)37(51)44(56)38(52)31-22(14-43(40,44)55)18(3)29-32(35(31)49)23(46)13-25(57-8)34(29)48/h9-10,13,20-21,24,26-27,39-40,47,49,51,54-56H,11-12,14-15H2,1-8H3/t20-,21+,24+,26+,27+,39-,40-,42-,43-,44-/m1/s1 |
| InChi Key | IFCBPTPGDINHLK-VSYKUZCLSA-N |
| Canonical SMILES | CC1C(CCC(O1)OC2C(=O)C(=C(C3(C2(CC4=C(C5=C(C(=O)C=C(C5=O)OC)C(=C4C3=O)O)C)O)O)O)C(=O)C)OC6CC(C(C(O6)C)OC(=O)C7=C(C=CC(=C7O)C)C)(C)O |
| Isomeric SMILES | C[C@@H]1[C@H](CC[C@@H](O1)O[C@@H]2C(=O)C(=C([C@@]3([C@]2(CC4=C(C5=C(C(=O)C=C(C5=O)OC)C(=C4C3=O)O)C)O)O)O)C(=O)C)O[C@H]6C[C@@]([C@@H]([C@@H](O6)C)OC(=O)C7=C(C=CC(=C7O)C)C)(C)O |
| PubChem CID | 5747698 |
| 分子量 | 864.84 |
| 溶解性 | Soluble in DMSO, methanol or acetone. |
|---|
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