,芝麻酚,3,4-亚甲二氧基苯酚|3,4-亚甲基二氧苯酚|1,3,4-苯三酚-3,4-缩甲醛|3,4-二亚甲氧基苯酚 | Sesamol|533-31-3|1,3-Benzodioxol-5-ol|3,4-Methylenedioxyphenol|3,4-(Methylenedioxy)phenol|5-Hydroxy-1,3-benzodioxole|3,4-Methylendioxyphenol|Met,Sesamol-阿拉丁试剂

货号 (SKU)	包装规格	是否现货
S106853-5g	5g	现货
S106853-10g	10g	期货
S106853-25g	25g	现货
S106853-100g	100g	现货
S106853-500g	500g	现货

基本描述

别名	3,4-亚甲二氧基苯酚\|3,4-亚甲基二氧苯酚\|1,3,4-苯三酚-3,4-缩甲醛\|3,4-二亚甲氧基苯酚
英文别名	Sesamol\|533-31-3\|1,3-Benzodioxol-5-ol\|3,4-Methylenedioxyphenol\|3,4-(Methylenedioxy)phenol\|5-Hydroxy-1,3-benzodioxole\|3,4-Methylendioxyphenol\|Methylene ether of oxyhydroquinone\|Phenol, 3,4-(methylenedioxy)-\|benzo[d][1,3]dioxol-5-ol\|2H-1,3-Benzodioxol-5-Ol\|
规格或纯度	98%
英文名称	Sesamol
储存温度	2-8°C储存,避光,充氩
运输条件	冰袋运输
产品介绍	芝麻酚天然存在於芝麻油中，含量极少。该产品系芳香族酚类化合物，可以与酸、醛、醇（酚）等化合物作用生成酯、醚衍生物,微溶于水。广泛用于制备防霉抗菌剂、抗癌、抗高血压药品、高档洗发香波的头发调理剂等一系列精细化学品，是昂贵的化学、医药中间体原料，具有较好地开发利用价值和应用前景。还是抗癌药物和农药增效剂合成的重要中间体，还作为抗高血压和脑血管疾病药物的中间体。 application： Sesamol has good antioxidant activity. Sesamol has potential protective effects against free radicals as well as some antifungal activity. Sesamol can also be used as an intermediate in the preparation of antidepressants such as Paroxetine (P205750). Sesamol has been found to be an antioxidant that may prevent the spoilage of oils. It also may prevent the spoilage of oils by acting as an antifungal. It is also used in ayurvedic Medicine.

名称和标识符

EC号	208-561-5
IUPAC Name	1,3-benzodioxol-5-ol
INCHI	InChI=1S/C7H6O3/c8-5-1-2-6-7(3-5)10-4-9-6/h1-3,8H,4H2
InChi Key	LUSZGTFNYDARNI-UHFFFAOYSA-N
Canonical SMILES	C1OC2=C(O1)C=C(C=C2)O
Isomeric SMILES	C1OC2=C(O1)C=C(C=C2)O
WGK Germany	3
RTECS	SM0890000
PubChem CID	68289
分子量	138.12
Beilstein号	127405
Reaxy-Rn	127405

化学和物理性质

溶解性	Soluble in methanol, water (partly), and dichloromethane (25 mg/ml).
密度	1.394
敏感性	对光敏感；对空气敏感
沸点	113°C/2mmHg
熔点	63-65°C

安全和危险性（GHS）

象形图	Health Hazard Harmful
信号词	Warning
危险声明	H315: Causes skin irritation H319: Causes serious eye irritation H335: May cause respiratory irritation H373: Causes damage to organs through prolonged or repeated exposure
预防措施声明	P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P260,P271,P304+P340,P403+P233,P362+P364,P264+P265,P337+P317,P332+P317,P319
WGK Germany	3
RTECS	SM0890000
Reaxy-Rn	127405
个人防护装备	dust mask type N95 (US),Eyeshields,Gloves

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参考文献

1. Aya Fujimoto,Yoshimi Shingai,Toshihisa B Oyama,Takuya Kawanai,Erika Hashimoto,Kazuki Koizumi,Kaori Kimura,Toshiya Masuda,Yasuo Oyama. (2010-06-01) Apoptosis-inducing action of two products from oxidation of sesamol, an antioxidative constituent of sesame oil: a possible cytotoxicity of oxidized antioxidant.. Toxicology in vitro : an international journal published in association with BIBRA, 24 ((6)): (1720-1726). [PMID:20510349]
2. Rekha R Shenoy,Arun T Sudheendra,Pawan G Nayak,Piya Paul,N Gopalan Kutty,C Mallikarjuna Rao. (2010-11-03) Normal and delayed wound healing is improved by sesamol, an active constituent of Sesamum indicum (L.) in albino rats.. Journal of ethnopharmacology, 133 ((2)): (608-612). [PMID:21035533]
3. C Mahendra Kumar,U V Sathisha,Shylaja Dharmesh,A G Appu Rao,Sridevi A Singh. (2010-12-15) Interaction of sesamol (3,4-methylenedioxyphenol) with tyrosinase and its effect on melanin synthesis.. Biochimie, 93 ((3)): (562-569). [PMID:21144881]
4. Srinivasan Periasamy,Shin Yi Chen,Dur-Zong Hsu,Ming-Yie Liu. (2011-01-07) Comments on Vennila and Pugalendi. Vennila L, Pugalendi KV. Protective effect of sesamol against myocardial infarction caused by isoproterenol in Wistar rats. Redox Rep 2010; 15: 36-42.. Redox report : communications in free radical research, 15 ((6)): (288-289). [PMID:21208529]
5. Yung-Chang Lu,Thanasekaran Jayakumar,Yeh-Fang Duann,Yung-Chen Chou,Cheng-Ying Hsieh,Shin-Yun Yu,Joen-Rong Sheu,George Hsiao. (2011-03-25) Chondroprotective role of sesamol by inhibiting MMPs expression via retaining NF-κB signaling in activated SW1353 cells.. Journal of agricultural and food chemistry, 59 ((9)): (4969-4978). [PMID:21428299]
6. Chifumi Kinugasa,Aki Naemura,Kanae Hyodo,Yoshiki Nakai,Masumi Katsuta,Junichiro Yamamoto. (2011-05-18) Experimental antithrombotic effects of sesame seed whole grains and extracts.. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 22 ((6)): (526-531). [PMID:21577091]
7. Ying-Hui Chen,Sew-Fen Leu,Chun-Yi Jen,Bu-Miin Huang. (2011-08-26) Effects of sesamol on apoptosis and steroidogenesis in MA-10 mouse Leydig tumor cells.. Journal of agricultural and food chemistry, 59 ((18)): (9885-9891). [PMID:21863802]
8. K Mishra,P S Srivastava,N K Chaudhury. (2011-09-09) Sesamol as a potential radioprotective agent: in vitro studies.. Radiation research, 176 ((5)): (613-623). [PMID:21899433]
9. Annia Galano,Juan Raúl Alvarez-Idaboy,Misaela Francisco-Márquez. (2011-10-05) Physicochemical insights on the free radical scavenging activity of sesamol: importance of the acid/base equilibrium.. The journal of physical chemistry. B, 115 ((44)): (13101-13109). [PMID:21967544]
10. P-Y Chu,P Srinivasan,J-F Deng,M-Y Liu. (2011-11-15) Sesamol attenuates oxidative stress-mediated experimental acute pancreatitis in rats.. Human & experimental toxicology, 31 ((4)): (397-404). [PMID:22076497]
11. Ashok Kumar Sharma,Saurabh Bharti,Jagriti Bhatia,Saroj Nepal,Salma Malik,Ruma Ray,Santosh Kumari,Dharamvir Singh Arya. (2012-03-09) Sesamol alleviates diet-induced cardiometabolic syndrome in rats via up-regulating PPARγ, PPARα and e-NOS.. The Journal of nutritional biochemistry, 23 ((11)): (1482-1489). [PMID:22398194]
12. Jesús F Arteaga,Mercedes Ruiz-Montoya,Alberto Palma,Gema Alonso-Garrido,Sara Pintado,José M Rodríguez-Mellado. (2012-05-05) Comparison of the simple cyclic voltammetry (CV) and DPPH assays for the determination of antioxidant capacity of active principles.. Molecules (Basel, Switzerland), 17 ((5)): (5126-5138). [PMID:22555300]
13. Jinliang Yang,Suqing Shi,Fei Xu,Jun Nie. (2012-10-11) Synthesis and photopolymerization kinetics of benzophenone sesamol one-component photoinitiator.. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 12 ((2)): (323-329). [PMID:23047776]
14. Soheila Kashanian,Ameneh Tahmasian Ghobadi,Hamideh Roshanfekr,Zohreh Shariati. (2012-10-17) DNA interaction studies of sesamol (3,4-methylenedioxyphenol) food additive.. Molecular biology reports, 40 ((2)): (1173-1179). [PMID:23070915]
15. Tian Yuan,Chuanqi Chu,Rubing Shi,Tianlin Cui,Xinglin Zhang,Yihang Zhao,Xu Shi,Yan Hui,Junru Pan,Rui Qian,Xiaoshuang Dai,Zhigang Liu,Xuebo Liu. (2019-05-24) ApoE-Dependent Protective Effects of Sesamol on High-Fat Diet-Induced Behavioral Disorders: Regulation of the Microbiome-Gut-Brain Axis.. Journal of agricultural and food chemistry, 67 ((22)): (6190-6201). [PMID:31117496]
16. S Ramachandran,N Rajendra Prasad,S Karthikeyan. (2010-08-11) Sesamol inhibits UVB-induced ROS generation and subsequent oxidative damage in cultured human skin dermal fibroblasts.. Archives of dermatological research, 302 ((10)): (733-744). [PMID:20697726]
17. Baldeep Kumar,Anurag Kuhad,Kanwaljit Chopra. (2010-11-26) Neuropsychopharmacological effect of sesamol in unpredictable chronic mild stress model of depression: behavioral and biochemical evidences.. Psychopharmacology, 214 ((4)): (819-828). [PMID:21103863]
18. Zhekang Ying,Nisharahmed Kherada,Thomas Kampfrath,Georgeta Mihai,Orlando Simonetti,Rajagopal Desikan,Karuppaiyah Selvendiran,Qinghua Sun,Ouiliana Ziouzenkova,Sampath Parthasarathy,Sanjay Rajagopalan. (2010-12-25) A modified sesamol derivative inhibits progression of atherosclerosis.. Arteriosclerosis, thrombosis, and vascular biology, 31 ((3)): (536-542). [PMID:21183734]
19. Gopakumar Gopinathan Nair,Cherupally Krishnan Krishnan Nair. (2011-01-06) Protection of cellular DNA and membrane from γ-radiation-induced damages and enhancement in DNA repair by sesamol.. Cancer biotherapy & radiopharmaceuticals, 25 ((6)): (629-635). [PMID:21204756]
20. Victor Raj Mohan Chandrasekaran,Se-Ping Chien,Dur-Zong Hsu,Ming-Yie Liu. (2011-01-18) Anti-hepatotoxic effects of 3,4-methylenedioxyphenol and N-acetylcysteine in acutely acetaminophen-overdosed mice.. Human & experimental toxicology, 30 ((10)): (1609-1615). [PMID:21239480]
21. Shubham Misra,Vinod Tiwari,Anurag Kuhad,Kanwaljit Chopra. (2011-04-06) Modulation of nitrergic pathway by sesamol prevents cognitive deficits and associated biochemical alterations in intracerebroventricular streptozotocin administered rats.. European journal of pharmacology, 659 ((2-3)): (177-186). [PMID:21463622]
22. Srinivasan Periasamy,Fan-E Mo,Shin-Yi Chen,Chih-Ching Chang,Ming-Yie Liu. (2011-04-08) Sesamol attenuates isoproterenol-induced acute myocardial infarction via inhibition of matrix metalloproteinase-2 and -9 expression in rats.. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 27 ((3-4)): (273-280). [PMID:21471716]
23. Srinivasan Periasamy,Dur-Zong Hsu,Shin-Yi Chen,Shan-Shan Yang,Victor Raj Mohan Chandrasekaran,Ming-Yie Liu. (2011-06-18) Therapeutic sesamol attenuates monocrotaline-induced sinusoidal obstruction syndrome in rats by inhibiting matrix metalloproteinase-9.. Cell biochemistry and biophysics, 61 ((2)): (327-336). [PMID:21681587]
24. Vandita Kakkar,Anil Kumar Mishra,Krishna Chuttani,Kanwaljit Chopra,Indu Pal Kaur. (2011-10-08) Delivery of sesamol-loaded solid lipid nanoparticles to the brain for menopause-related emotional and cognitive central nervous system derangements.. Rejuvenation research, 14 ((6)): (597-604). [PMID:21978086]
25. Chao-Chien Chang,Wan-Jung Lu,Eng-Thiam Ong,Cheng-Wen Chiang,Song-Chow Lin,Shih-Yi Huang,Joen-Rong Sheu. (2011-12-16) A novel role of sesamol in inhibiting NF-κB-mediated signaling in platelet activation.. Journal of biomedical science, 18 (): (93-93). [PMID:22168157]
26. Lakshmanan Vennila,Kodukkur Viswanathan Pugalendi. (2012-09-04) Efficacy of sesamol on plasma and tissue lipids in isoproterenol-induced cardiotoxicity in Wistar rats.. Archives of pharmacal research, 35 ((8)): (1465-1470). [PMID:22941490]
27. Zhigang Liu,Qisen Xiang,Lihui Du,Ge Song,Yutang Wang,Xuebo Liu. (2013-06-19) The interaction of sesamol with DNA and cytotoxicity, apoptosis, and localization in HepG2 cells.. Food chemistry, 141 ((1)): (289-296). [PMID:23768360]

芝麻酚

库存信息

库存信息

库存信息

库存信息

库存信息

基本描述

名称和标识符

化学和物理性质

安全和危险性（GHS）

质检证书(COA)

质检报告(COA)

相关文档

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参考文献