FOOD CHEMISTRY
·
2024
·
IF 8.5
Luan Huang,Xin Zhou,Qingyun Chang,Shuaihua Zhang,Zhi Wang,Chun Wang,Xiaohuan Zang
Sulfonamide antibiotics have a broad spectrum of antibacterial action and are widely used, but their overuse poses a threat to human health. In this study, a three-dimensional conjugated microporous polymer, which was designated as TPM-CMP, was synthesized via Friedel-Crafts reaction by using tetraphenylmethane (TPM) and biphenyl dichlorobenzene as monomers, and it was utilized as an adsorbent in solid-phase extraction (SPE) of sulfonamides. The TPM-CMP demonstrated high extraction efficiency for sulfonamides due to π -stacking interactions, hydrophobic forces, and pore-filling effects. Consequently, the SPE was combined with liquid chromatography to detect sulfonamides in milk samples. For this method established in this study, a good linear response was observed in the range of 3.3–300.0 ng g −1 , with a detection limit ( S/N = 3) between 1.0 and 1.5 ng g −1 . The method recoveries of four sulfonamide in milk samples ranged from 83.4 % to 117 %, with relative standard deviations below 10 %.
研究领域:
分析化学
·
环境科学
✓ 已验证
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Zong-Mu Dong,Yaqing Guo,Liming Qin,Peiyi Zhang,Jian-Feng Wu,Guang-Chao Zhao
A multi-step growing and etching method was used to synthesize metal–organic framework materials (MIL-101) with a hollow structure of distinct shell layers. The resorcinol–formaldehyde organic aerogel (RFOA) was embedded in-situ into the triple-shelled hollow MIL-101 (TSHM) to form a novel RFOA@TSHM spherical multilayer shell composite, which was used as a fiber coating material of solid-phase microextraction for the enrichment and determination of six tetracyclines (TCs) by coupling with HPLC-UV–vis detector in aqueous solutions. Due to the embedding of the RFOA and the multilayer shell structure, the RFOA@TSHM composite is characterized by a stable structure with a larger pore size and specific surface area compared with the TSHM alone. Under optimal conditions, limits of detection of 0.13–1.16 μg L −1 and limits of quantification of 0.43–3.83 μg L −1 were obtained for TCs detection. Moreover, the RFOA@TSHM coating fiber was successfully applied to detect TCs in egg and milk real samples.
研究领域:
分析化学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2014
·
IF 3.259
Peijin Wang,Yu Xiao,Wenjun Liu,Juan Wang,Yaling Yang
A rapid, simple, sensitive and environmentally friendly method has been developed for the determination of three oestrogens (17β-estradiol (17β-E2), estrone (E1), and diethylstilbestrol (DES)) in milk samples by using vortex-assisted hollow fibre liquid-phase microextraction (VA-HF-LPME) and high performance liquid chromatography. Method is based on the microextraction of oestrogens from sample solution into 15 μL of nonanoic acid as extracting agent, which is placed inside the hollow fibre followed by vortex-mixing. Vortex provided effective and mild mixing of sample solution and increased the contact between analytes and boundary layers of the hollow fibre, thereby enhancing mass transfer rate and leading to high recovery of target analytes. The extraction equilibrium is achieved within 2 min. Parameters influencing the recovery were investigated and optimized. The proposed technique provided good linearity (>0.9984), repeatability (RSD = 2.56–4.38), low limits of detection (0.06–0.17 ng mL −1 ), and high enrichment factor (330).
研究领域:
分析化学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CRYSTENGCOMM
·
2025
·
IF 2.6
Yuting Luo,Yiwei Sun,Haoxiang Wang,yuyang He,Mengqi Lu,Ruoyu Wang,Dongpo Xu
Due to the wide application of tetracycline (TC), there will be residues in human daily food. It is important to develop sensitive and rapid detection methods for TC in food. In this study, a rod-like NH2-MIL-68 (In) material was developed as a DNA probe binding site for rapid detection of TC. The aptamer and NH2-MIL-68 (In) were tightly bound by glutaraldehyde. After the addition of TC, the aptamer specifically adsorbs TC in the test sample, resulting in increased impedance on the electrode and decreased electrical signal. Under optimized conditions, the sensor had a wide detection range (0.001-100 μM) and a low detection limit (0.36 nM). In addition, the NH2-MIL-68 (In)@Apta sensor was successfully applied to TC residues in milk samples with recoveries of 84.33 % -117.22 %. The results showed that our work can provide a new strategy for the direct detection of TC in food samples.
研究领域:
食品科学
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分析化学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
RSC Advances
·
2015
·Vol. 5
·期 35
·27458-27463
·
IF 3.84
Jintai Lin,Qianming Wang
The design, synthesis, photophysical properties and practical application of fluorescent silicon nanoparticles (SiNPs) of a quantum-size (∼3 nm) have been studied. 3-Aminopropyltrimethoxysilane (APTMS) and 3-aminopropyltriethoxysilane (APTES) were employed as sources. The newly developed nanoparticles show excellent water solubility and luminescent features. Herein we report a novel chemical approach for selective tetracycline (TC) recognition and a new type of targetable fluorescent sensor has been prepared. The blue emission, peaking at 440 nm, was dramatically quenched in the presence of TCs. Moreover, we utilized this probe in a milk sample study for the determination of TCs, demonstrating its advantages of simplicity and practicality.
研究领域:
生物化学
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材料科学
·
分析化学
✓ 已验证
DOI
高影响因子
Food Analytical Methods
·
2022
·Vol. 15
·期 7
·2036-2047
·
IF 3.498
Gao Ming,Wang Hui,Wang Jun,Wang Xuedong,Wang Huili
Herein, we developed an effervescent reaction-enhanced dispersive liquid–liquid microextraction method for the preconcentration/extraction of bisphenols (BPs) in milk and milky tea samples. This microextraction method was based on the utilization of acidic ionic liquid (AIL) and in situ metathesis reaction (AI-EDLM). Compared to the traditional imidazolium-based ionic liquid, AIL can not only be used as an extractant, but also as an acidic source in the effervescent reaction. Under such a case, it can avoid the use of additional acidic source and also achieve a rapid dispersion effect due to vigorous CO 2 bubbles, which simplify the experimental procedures and decrease the preparation cost of effervescent tablets. By employing the one-factor-at-a-time approach, the main parameters were optimized as follows: 400 mg of [BMIM][HSO 4 ] as extractant, 100 mg of Na 2 CO 3 as alkaline source, 400 mg of Li[NTf] 2 as the ionic-exchange reagent, 4% of NaCl, 5 min of centrifugation and 1.5 mL of ether as the elution solvent. Under optimized conditions, the limits of detection ranged from 0.12 to 0.32 μg L −1 , and the extraction recoveries for BPA, BPB, and BPAF spanned the range of 85.7–106.2% in five kinds of milk samples. Therefore, the AIL ([BMIM][HSO 4 ]) played dual roles, i.e., extractant and pH regulator, in the AI-EDLM procedures. Overall, this proposed method is simple, quick, and environment-friendly with low detection limits and high recoveries for BPs, and thus has excellent application value in the sample pretreatment field in milk and milky tea samples.
研究领域:
分析化学
·
环境科学
✓ 已验证
DOI
高影响因子
RSC Advances
·
2021
·Vol. 11
·期 12
·6869-6876
·
IF 3.361
Shuai Zhang,Huachun Liu,Tianpei Cai,Yanqiang Zhou,Jianmin Li,Xiaoxiao Wang,Shanwen Zhao,Chunmiao Bo,Bolin Gong
Taking thiamphenicol as the research object, a new type of magnetic restricted access molecularly imprinted polymer (RAM-MMIP) with specific recognition was prepared by a one-step swelling method. The polymer microspheres were characterized and analyzed by scanning electron microscopy, X-ray diffraction, elemental analysis, contact angle measurement and vibrating sample magnetometry. When the ratio of template molecule, functional monomer and cross linking agent was 1 : 4 : 8, the adsorption capacity reached the maximum. Under these conditions, RAM-MIP magnetic solid phase extraction (M-SPE) was combined with HPLC to analyze thiamphenicol in milk samples. Satisfactory linear correlation (R2 > 0.9977), good detection limit (LOD: 10.4 μg L−1), high recovery rate (96.5–101.1%), and relative standard deviation (RSD: 2.8–3.8%) were obtained. Therefore, our synthesized material can be used for the analysis of TAP in complex milk samples, and has broad application value.
研究领域:
食品科学
·
分析化学
✓ 已验证
DOI
高影响因子
FOOD CHEMISTRY
·
2024
·
IF 8.5
Hongmei Liu,Yue Li,Sikai Wang,Sisi Zhang,Guoqi Zhang,Yan Zhao
Herein, a new, environmentally friendly, and economical magnetic solid-phase extraction method for fluoroquinolones (FQs) from milk samples was developed using novel recyclable zeolitic imidazolate framework functionalized magnetic multiwalled carbon nanotubes (Fe 3 O 4 @MWCNTs@SiO 2 @ZIF-8) as adsorbents. Various characterization techniques, including scanning electron microscopy, N 2 adsorption-desorption analysis, and vibrating sample magnetometry, demonstrated that the adsorbent possessed a remarkable specific surface area, pore volume, and superparamagnetic properties, rendering it an excellent adsorbent. Combined with high-performance liquid chromatography, this method exhibited excellent linearity (R 2 ≥ 0.9991) over the concentration range of 0.5–500 μg L −1 , low limits of detection (0.10–0.34 μg kg −1 ), and low limits of quantification (0.30–1.00 μg kg −1 ). Finally, the developed method was successfully applied to analyze FQs in milk samples with recoveries ranging from 83.3% to 107.7% and relative standard deviations below 4.2%. The high efficiency and sensitivity of this method highlight the potential application of Fe 3 O 4 @MWCNTs@SiO 2 @ZIF-8 for analyzing FQs in complex matrices.
研究领域:
分析化学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Yan Qiao,Menglin Wang,Erling Guo,Ke Wang,Ling Ma,Kaoqi Lian
This study aimed to design and synthesize a novel adsorbent Fe 3 O 4 @SiO 2 @MPA-TAPA-COF material for the first time and used as an adsorbent of MSPE. It had significant potential for the pretreatment of trace analytes. The MSPE was coupled with ultra performance liquid chromatography–tandem mass spectrometry (UPLC-MS/MS) for the rapid extraction and detection of 12 sulfonamides (SAs) from water and milk samples for the first time. Several experimental parameters were optimized, including adsorbent dosage and the effects of pH, ionic strength, adsorption time, and desorption conditions. Under the optimized pretreatment and instrumental conditions, good linearity of 0.1–100 μg·L −1 with a correlation coefficient 0.9994–0.9999, low limits of detection (0.004–0.044 μg·L −1 ) and limits of quantitation (0.013–0.136 μg·L −1 ) were obtained. Moreover, the recoveries of sulfonamides in water and milk samples were in the range of 60.88 %-102.94 %, and the relative standard deviations not exceeding 9.62 %. Finally, the magnetic Fe 3 O 4 @SiO 2 @MPA-TAPA-COF material possessed the magnetic separation and high adsorption affinity for extracting SAs from real samples. This study holds great significance in enhancing the monitoring of SAs drug residues in water and milk.
研究领域:
分析化学
·
环境科学
·
食品科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
·
2024
·
IF 4
Wanling Cui,Churuo Hu,Rui Zhu,Dewen Qiu,Ruihong Gong,Rui Wang,Qiang Li,Tingting Yan,Chonghui Li,Mei Qiao,Shicai Xu
The detection of kanamycin has attracted extensive attention in the field of food safety. A label-free, low-background fluorescent biosensor was successfully constructed based on graphene oxide and aptamer biorecognition in this paper for kanamycin detection in milk samples. In this biosensor, the integrated probe with the aptamer sequence of kanamycin and the G-rich sequence was designed. The aptamer sequence of kanamycin was used as the recognition part, the G-quadruplex/N-methyl mesoporphyrin IX (NMM) complex as the fluorescent probe, and graphene oxide as the fluorescent quencher. Initially, the integrated probe could be adsorbed on the graphene oxide surface through π-π stacking interactions, while the fluorescence of NMM could be efficiently quenched because of the resonance energy transfer between NMM and graphene oxide, which was beneficial to the low background signal of the system. During the detection process, the aptamer sequence preferred to bind to kanamycin, forming aptamer-kanamycin complex. At the same time, the G-rich sequence folded into G-quadruplex structure that specifically bound to NMM under the action of K + , forming G-quadruplex/NMM complex. Under the synergistic effects of the two complexes, the integrated probe with aptamer-kanamycin complex and G-quadruplex/NMM complex was released from the graphene oxide surface due to the steric hindrance effect, restoring the strong fluorescence signal. By combining graphene oxide and G-quadruplex/NMM complex, the fluorescent biosensor could effectively achieve label-free and low-background detection of kanamycin. The linear calibration curve was in the range of 1–400 nM with a detection limit of 0.60 nM for kanamycin. It was successfully applied to analyze raw milk samples (spiked kanamycin) with recoveries of 98.33–101.25 % and also exhibited high selectivity for kanamycin. The experimental data showed that the biosensor was a potentially powerful tool for monitoring food safety.
研究领域:
食品安全
·
生物传感
·
分子识别
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
·
2019
·
IF 2.813
Shiqian Gao,Yiqiu Wu,Siyuan Xie,Zichun Shao,Xiumin Bao,Yumeng Yan,Youyi Wu,Junxia Wang,Zhanen Zhang
The ionic liquid (IL) was introduced to the synthesis system of magnetic zeolite imidazolate framework-8 (M/ZIF-8), which was benefit to the formation of binary imidazole and the co-modification of M/ZIF-8. The morphology and textural properties of ILM/ZIF-8 were characterized by SEM, TEM , BET and BJH. The crystal structural shape and size of MZIF-8 was unvaried with the interventional of IL. The ILM/ZIF-8 was applied to the concentration and determination of aflaoxins (AFB 1 , AFB 2 , AFG 1 and AFG 2 ) in milk samples based on magnetic solid phase extraction (MSPE) coupled with ultra high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS). The experimental parameters of the MSPE, including amount of ILM/ZIF-8, pH, type and amount of desorption solvent, extraction time and sample volume were investigated by a univariate method and orthogonal screening. The four AFs were concentrated from the 20 mL milk when 90 mg ILM/ZIF-8 was used as magnetic adsorbent. The extraction efficiency of AFs was higher than 80.0% within 15 min. The limits of quantitative and detection were 7.5–26.7 and 2.3–8.1 ng/L, respectively. The proposed method was applied to the determination of milk samples containing trace amounts of AFs and the recoveries ranged from 79.0% to 102.5%, with RSD below 7.7%.
研究领域:
食品科学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2018
·Vol. 42
·期 4
·2857-2864
·
IF 3.201
Chunxi Zhao,Yang Jiao,Lei Zhang,Yaling Yang
Herein, we report a fast and selective technique for the determination of diethylstilbestrol in milk sample using fluorescent sulfur and boron co-doped carbon dots (S,B co-doped CDs). The S,B co-doped CDs were synthesized by hydrothermal synthesis using poly(sodium-p-styrenesulfonate) and borax as precursors. The as-prepared S,B co-doped CDs possess good stability and fluorescence characteristics and exhibit a fluorescence quantum yield of 25.7%. The fluorescence intensity of the S,B co-doped CDs decreased in the presence of diethylstilbestrol, and a good linear relationship existed between the fluorescence quenching and different concentrations of diethylstilbestrol in the range of 0.1–200 μM with a detection limit of 0.06 μM. Finally, the S,B co-doped CDs were successfully applied in the detection of diethylstilbestrol in milk samples, yielding recoveries between 90.4% and 109.2%.
研究领域:
分析化学
·
食品科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）