SCIENCE OF THE TOTAL ENVIRONMENT
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2021
·
IF 7.963
Yu-jie Wang,Yi Yu,Hua-jun Huang,Cheng-long Yu,Han-sun Fang,Chun-huo Zhou,Xin Yin,Wei-hua Chen,Xin-chun Guo
The treatment of sewage sludge (SS) is an environmental problem worldwide. In recent years, hydrothermal carbonization (HTC) of SS for hydrochar (HC) has attracted extensive attention. This study preliminarily explored the microwave-assisted HTC of SS for the first time. Increasing the reaction temperature (150–250 °C) and reaction time (0–120 min) resulted in a decrease in the HC yield, and it gradually increased with the rising solid–liquid ratio (0.03–0.25 g/mL). Compared with raw SS, the HC products possessed higher aromaticity, carbonization degree, porosity, and polarity, and lower content of soluble nutrients (N/P/K) and leachable heavy metals (Cu, Zn, Pb, Cd, Cr, and Ni), indicating a lower risk of nutrient and heavy metal loss. Attention should be paid to the total contents of Zn and Cd in HC exceeded the permitted value for use in cultivated land with edible crops. The use of CaO as a catalyst improved the yield of HC, made the HC and process water (PW) weakly alkaline, and further passivated the heavy metals in the HC. In the case of H 3 PO 4 , although the conversion of SS was enhanced (lower content of volatile organic matter in HC), the contents of soluble nutrients (N/P/K) in HC/PW increased, and the migration of Zn and Cd into process water was enhanced. The HCs obtained in this study had poor combustion properties, but higher ignition temperatures than raw SS. PW must be properly treated or recycled because it still contained high contents of organic matter and nutrients. This fundamental study provides basic insights into the microwave-assisted HTC of SS.
研究领域:
环境科学
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能源工程
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产品关联
DOI
PubMed
高影响因子
LWT-FOOD SCIENCE AND TECHNOLOGY
·
2022
·
IF 6.056
Wei Jia,Xixuan Wu,Rong Zhang,Xin Wang,Lin Shi
The migration of perchlorate into dairy products through water or detergent is becoming increasingly serious. Spatiotemporal profiles of lipid nutrients associated with perchlorate response were investigated by spatial multi-omics of goat milk. In response to perchlorate accumulation, lipoprotein lipase activity was inhibited in glycerolipid metabolism, thereby resulting in the excessive accretion of triglycerides. Goat milk was selected as the test matrix and conducted to simulate the biological cumulation of perchlorate and evaluate effects of different dietary perchlorate levels (0.0–2.0 mg/kg) on nutritional quality of goat milk. Perchlorate altered phospholipase A 2 expression level, affected glycerophospholipid metabolism thus triggered significant changes in phosphatidylcholine (23.35–31.88 μg/mL). Excess triacylglycerol accumulation (3259–6032 μg/mL) caused by perchlorate was due to the inhibition of glycerolipid metabolism mediated by lipoprotein lipase. The study indicated that dietary perchlorate exposure resulted in the decline of nutritional quality in goat milk, which indirectly posed a serious threat to the health of consumers.
研究领域:
食品科学
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环境毒理学
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分子生物学
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产品关联
DOI
高影响因子
Food Chemistry-X
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2024
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IF 6.5
Ibrahim Khalifa,Remah Sobhy,Xiaobo Zou,Asad Nawaz,Noman Walayat,Putri Widyanti Harlina,Tarek Kh. Abdelkader,Mukhtar Ahmed,Sajid Maqsood
The effect of non-thermal (HPP and semi-HPP-CO 2 ) and thermal (flash pasteurization, FP) treatments on phytonutrients of flowable smoothie prepared from quadrable vegetable blends (FQVS) was investigated using multidimensional methods. First, FQVS gained an acceptability sensorial index (85.7%) compared with other formulas. FQVS/semi-HPP-CO 2 showed a greater microbial stability during storage (0–30 d) compared to HPP and FP. Fructose and glucose highly declined than sucrose in all smoothies, where semi-HPP-CO 2 steadily declined this reduction during storage. LC/MS-MS analysis showed that semi-HPP-CO 2 preserved most of FQVS's phytonutrients and their antioxidant effects measured by ORAC and oxidative enzymes inhibition assays. Semi-HPP-CO 2 acquired the lowest apparent viscosity among different FQVS smoothies, showing its post-processing flowability behavior. Most importantly, semi-HPP-CO 2 predicted a reduced power consumption for HPP and reduced the gas emission. In conclusion, blending different vegetables assisted with semi-HPP-CO 2 could be a novel approach to produce storage-stable smoothies with adequate amounts of phytonutrients and sensorial scores.
研究领域:
食品科学
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植物学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
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2025
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IF 4.6
Li Zhou,Tianyu Zhang,Timothy J. Tse,Martin J.T. Reaney,Siya Zhao,Zilun Cao,Shu Wang,Zhigang Hu,Bin Li,Chuanrong Hu,Dongping He,Fenfen Lei,Qinfeng Zhang
Degumming, a critical process in the edible oil industry, is essential for removing phospholipids. Traditional methods such as water-degumming and acid-degumming have limitations in this regard. This study aimed to assess the efficacy of different degumming techniques, including acid, single and multi-enzyme methods, on rice bran oil (RBO). The investigation also focused on the impact of these techniques on the physicochemical characteristics and preservation of micronutrients in RBO during the degumming process. The primary phospholipids identified were phosphatidylethanolamine (29.51%), phosphatidylcholine (37.00%), and phosphatidylinositol (24.49%). Acid degumming removed 84.23% of phospholipids, while a significantly higher removal rate of 98.7% was achieved with the combination of phospholipase A1 & phospholipase C. The degumming process effectively inhibited oxidation in RBO, leading to a substantial increase in the oxidation induction time from 5.7 to 10.0 hours. Furthermore, multi-enzyme degumming showed slightly greater radical-scavenging activity compared to single enzyme degumming in RBO. However, the levels of micronutrients such as phenols, sterols, tocopherols, squalene, and oryzanol were reduced by 6.27% to 22.17%. This study provides a comprehensive analysis of the effects of different degumming processes on the physicochemical properties, fatty acid profiles, antioxidant capacities, and preservation of micronutrients in RBO.
研究领域:
食品科学
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生物化学
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产品关联
DOI
高影响因子
Crystals
·
2019
·Vol. 9
·期 11
·559
·
IF 2.061
Jingyu Sun,Yunhe Zhou,Yajuan Su,Sheng Li,Jingmei Dong,Qing He,Yang Cao,Tianfeng Lu,Lili Qin
Resveratrol (RSV) has various pharmacological effects; however, few studies have directly addressed the possible antifatigue effects of long-term endurance exercise. The clinical use of RSV is limited by its poor water solubility and extremely short plasma half-life. Solid lipid nanoparticles (SLNs) are considered as reasonable drug delivery systems to overcome some of these drawbacks and expand its applications. In this study, RSV-SLNs were successfully prepared through emulsification and low-temperature solidification. Results showed that RSV-SLN supplementation effectively enhanced endurance performance. RSV-SLN supplementation might enhance mitochondrial function by ameliorating mitochondrial quality control (QC), which was superior to RSV application. These results revealed an unexpected role of RSV-SLN compared with RSV in terms of linking nutrient deprivation to mitochondrial oxidant production through mitochondrial QC. A mitochondrion-mediated pathway was likely involved in RSV-SLN, thereby improving endurance performance. Overall, this study highlighted new possibilities for anti-physical-fatigue strategies.Keywords:resveratrol;solid lipid nanoparticles;endurance exercise;mitochondrial nutrients;mitochondrial quality control
研究领域:
药理学
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运动科学
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纳米技术
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线粒体生物学
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DOI
高影响因子
Nanomaterials
·
2022
·Vol. 12
·期 4
·687
·
IF 5.719
Hua Pan,Weilan Huang,Litao Wu,Qihao Hong,Zhongxuan Hu,Meijing Wang,Fang Zhang
Integrating pesticides and mineral elements into a multi-functional stimuli-responsive nanocarrier can have a synergistic effect on protecting plants from pesticides and the supply of nutrients. Herein, a pH dual-responsive multifunctional nanosystem regulated by coordination bonding using bimodal mesoporous silica (BMMs) as a carrier and coordination complexes of ferric ion and polymethacrylic acid (PMAA/Fe3+) as the gatekeeper was constructed to deliver prochloraz (Pro) for the smart treatment of wilt disease (Pro@BMMs−PMAA/Fe3+). The loading capacity of Pro@BMMs−PMAA/Fe3+nanoparticles (Nps) was 24.0% and the “PMMA/Fe3+” complexes deposited on the BMMs surface could effectively protect Pro against photodegradation. The nanoparticles possessed an excellent pH dual-responsive release behavior and better inhibition efficacy againstRhizoctonia solani. Fluorescence tracking experiments showed that Nps could be taken up and transported in fungi and plants, implying that non-systemic pesticides could be successfully delivered into target organisms. Furthermore, BMMS−PMAA/Fe3+nanocarriers could effectively promote the growth of crop seedlings and had no obvious toxicological influence on the cell viability and the growth of bacteria. This study provides a novel strategy for enhancing plant protection against diseases and reducing the risk to the environment.Keywords:prochloraz;mesoporous silica nanoparticles;pH-responsive release;micronutrient;biosafety
研究领域:
植物保护
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纳米材料科学
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农业科学
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产品关联
DOI
PubMed
高影响因子
Journal of Functional Foods
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2025
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IF 4
Yuting Jian,Xiaoqun Zhong,Junjing Wang,Feijie Wang,Shaokun Yu,Jiannan Guo,Xiaona Gan,Juntao Kan,Wei Guo
Hyperuricemia (HUA) is an independent risk factor for cardiovascular disease, chronic kidney disease, and gout. This paper explored a novel phytonutrients formula (PNF) for managing HUA. PNF's efficacy was evaluated through in vitro , in vivo , and in silico studies. Phytochemical profiling of PNF was performed using advanced chromatography. In vitro enzymatic assay and cell studies demonstrated key mechanisms of inhibiting xanthine oxidase (XOD) and promoting uric acid (UA) excretion. In hyperuricemia mice model, PNF significantly reduced plasma UA level, inhibited XOD activity, enhanced UA excretion, and demonstrated antioxidant effects. Potential molecular targets were predicted, and hyperuricemia-related genes were curated. Protein-protein interaction networks and functional enrichment analyses were conducted to elucidate underlying mechanisms. In conclusion, PNF ameliorates HUA by inhibiting UA production, enhancing its excretion and exerting multi-target anti-inflammatory and antioxidant effects, highlighting its potential for HUA management.
研究领域:
药理学
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生物信息学
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分子生物学
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产品关联
DOI
高影响因子
BIOLOGICAL TRACE ELEMENT RESEARCH
·
2021
·Vol. 200
·期 3
·1408-1417
·
IF 3.738
Liu Peng,Xiao Weiwei,Wang Kai,Yang Zhaoguang,Wang Lin
Rice and rice products are the main sources of Cd contamination in humans. The total and bioaccessible concentrations of Cd and three divalent nutrients, Mn, Cu, and Zn, in locally grown rice grains from Hunan and Guangdong Provinces in China were investigated. An in vitro physiologically based extraction test method was introduced to evaluate the bioaccessibility of the target metals in the rice grains. The mean concentrations of Cd in the rice grains were 0.245 mg/kg and 0.235 mg/kg from Hunan and Guangdong Provinces, respectively. Large variations were observed in the Cd concentrations, indicating a heterogeneous distribution of Cd contamination throughout the study areas. The bioaccessibility of Cd, Mn, and Zn in the gastrointestinal fractions was significantly lower than that in the gastric fractions. In contrast, the bioaccessibility of Cu at the intestinal phase was detected in the rice grains from both provinces. The correlation analysis showed significant relationships between total Cd concentrations and bioaccessible Cd fractions, indicating that higher total Cd in rice grains always resulted in higher bioaccessible Cd. Consistent correlations in the rice grains were observed between Zn and Mn. However, a lack of correlation was found between Cd and Zn in the current study. Risk assessment according to bioaccessible Cd would significantly reduce the exposure risk to Cd from rice consumption.
研究领域:
环境科学
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食品安全
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毒理学
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营养学
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DOI
PubMed
高影响因子
JOURNAL OF DAIRY SCIENCE
·
2023
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IF 3.5
Danping Jin,Xinyue Yu,Qingcheng Wang,Xi Chen,Min Xiao,Haifeng Wang,Yiwei Cui,Weibo Lu,Lijun Ge,Ying Yao,Xiaoli Zhou,Jiahui Wu,Shikai Jian,Huijuan Yang,Ye Tao,Qing Shen
ABSTRACT Hypothyroidism has been found to have an impact on the nutritional composition of human milk during pregnancy. This study aims to explore the combined influence of rheological properties, macronutrient content, particle size, and the zeta-potential of milk fat globules as well as the composition of milk fat globule membrane (MFGM) proteins on the quality of human milk in gestational hypothyroidism. The study revealed that human milk from hypothyroidism during pregnancy (AHM) was less viscoelastic and stable when compared with normal pregnancy group human milk (NHM). Furthermore, the particle size and macronutrient content of NHM were found to be larger than that of AHM. On the other hand, the zeta-potential of AHM was greater than that of NHM. The SDS-PAGE results disclosed that the composition of MFGM proteins in these 2 groups were generally the same, but the content of AHM was lower than that of NHM. In conclusion, this study confirms that hypothyroidism during pregnancy can have a significant impact on the quality of human milk.
研究领域:
营养学
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妇产科学
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内分泌学
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食品科学
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DOI
PubMed
高影响因子
INDUSTRIAL CROPS AND PRODUCTS
·
2024
·
IF 5.6
Weikang Shen,Haobo Wang,Zhouzhe Lan,Guangzhi Xu,Qinxue Ni,Qiufen Mo,Youzuo Zhang,Yan Wang
Gardenia fruit oil (GFO) is a new emerging edible woody oil with few investigations of its’ refinement process. In this study, different degumming, deacidification and bleaching technologies were introduced for realizing moderate refining of the GFO based on the preservation of bioactive micronutrients. Firstly, a simple multi-stage solid phase extraction (SPE) combined with a lab- affordable HPLC-UV instrument was developed for determinations of several vital biological constituents, such as crocetin, geniposide, polyphenols, phytosterols and squalene in the GFO. Satisfactory limit of detection (LOD), limit of quantification (LOQ), recovery, intra-day and inter-day precision were obtained. Subsequently, changes of those phytochemicals during three types of degumming, followed by three kinds of deacidification and then three ways of bleaching were investigated, offering insightful suggestions for achieving moderate refining of the GFO. Finally, the refined GFO might be suggested as a potential functional edible oil with valuable micronutrients. To our knowledge, this is the first study investigating moderate refinement techniques for GFO, as well as developing novel methods for phytonutrients analysis in the GFO.
研究领域:
食品科学
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分析化学
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植物化学
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产品关联
DOI
高影响因子
BRAIN RESEARCH
·
2021
·
IF 3.252
Shuai-Nan Zheng,Long Pan,Ai-Mei Liao,Yin-Chen Hou,Guang-Hai Yu,Xiao-Xiao Li,Yong-Jian Yuan,Yu-Qi Dong,Zi-Shan Zhang,Cui-Zhu Tian,Zeng-Liang Liu,Wen-Jin Lin,Ming Hui,Jian Cao,Ji-Hong Huang
Wheat embryo globulin nutrient (WEGN), with wheat embryo globulin (WEG) as the main functional component, is a nutritional combination that specifically targets memory impairment. In this study, we explored the protective role of WEGN on Alzheimer's disease (AD)-triggered cognitive impairment, neuronal injury, oxidative stress, and acetylcholine system disorder. Specifically, we established an AD model via administration of d -galactose ( d -gal) and Aluminum chloride (AlCl 3 ) for 70 days, then on the 36th day, administered animals in the donepezil and WEGN (300, 600, and 900 mg/kg) groups with drugs by gavage for 35 days. Learning and memory ability of the treated rats was tested using the Morris water maze (MWM) and novel object recognition (NOR) test, while pathological changes and neuronal death in their hippocampus CA1 were detected via HE staining and Nissl staining. Moreover, we determined antioxidant enzymes by measuring levels of superoxide dismutase (SOD), malondialdehyde (MDA), and glutathione peroxidase (GSH-Px) in serum, cortex, and hippocampus, whereas changes in the acetylcholine system were determined by evaluating choline acetyltransferase (ChAT), and acetylcholinesterase (AChE) activities, as well as choline acetylcholine (Ach) content. Results revealed that rats in the WEGN group exhibited significantly lower escape latency, as well as a significantly higher number of targeted crossings and longer residence times in the target quadrant, relative to those in the model group. Notably, rats in the WEGN group spent more time exploring new objects and exhibited lower damage to their hippocampus neuron, had improved learning and memory activity, as well as reversed histological alterations, relative to those in the model group. Meanwhile, biochemical examinations revealed that rats in the WEGN group had significantly lower MDA levels and AChE activities, but significantly higher GSH, SOD, and ChAT activities, as well as Ach content, relative to those in the model group. Overall, these findings indicate that WEGN exerts protective effects on cognitive impairment, neuronal damage, oxidative stress, and choline function in AD rats treated by d -gal/AlCl 3 .
研究领域:
神经科学
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营养学
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药理学
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生物化学
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产品关联
DOI
PubMed
高影响因子
LIFE SCIENCES
·
2023
·
IF 6.1
Mei-Ling Lai,An-Qi Li,Alistair M. Senior,G. Gregory Neely,Stephen J. Simpson,Qiao-Ping Wang
Aims Sleep is a fundamental physiological function and is essential for all animals. Sleep is affected by diet compositions including protein (P) and carbohydrates (C), but there has not been a systematic investigation on the effect of dietary macronutrient balance on sleep. Main methods We used the nutritional geometry framework (NGF) to explore the interactive effects on sleep of protein (P) and carbohydrates (C) in the model organism Drosophila . Both female and male flies were fed various diets containing seven ratios of protein-to-carbohydrates at different energetic levels for 5 days and sleep was monitored by the Drosophila Activity Monitor (DAM) system. Key findings Our results showed that the combination of low protein and high carbohydrates (LPHC) prolonged sleep time and sleep quality, with fewer sleep episodes and longer sleep duration. We further found that the effects of macronutrients on sleep mirrored levels of hemolymph glucose and whole-body glycogen. Moreover, transcriptomic analyses revealed that a high-protein, low-carbohydrate (HPLC) diet significantly elevated the gene expression of metabolic pathways when compared to the LPHC diet, with the glycine, serine, and threonine metabolism pathway being most strongly elevated. Further studies confirmed that the contents of glycine, serine, and threonine affected sleep. Significance Our results demonstrate that sleep is affected by the dietary balance of protein and carbohydrates possibly mediated by the change in glucose, glycogen, glycine, serine, and threonine.
研究领域:
营养学
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睡眠科学
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分子生物学
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遗传学
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）