,长春胺,长春胺 | 太司尼克酸 | 长春花素 | 长春花胺 | 长春蔓胺 | HMS2095H04 | C09251 | DTXSID9040134 | Methyl vincaminate | Oxybral | Tox21_111342_1 | Tripervan | Vincamina [DCIT] | VINCAMINE [MART.] | Anasclerol (base)

货号 (SKU)	包装规格	是否现货
V107385-250mg	250mg	现货
V107385-1g	1g	现货
V107385-5g	5g	现货
V107385-25g	25g	现货

基本描述

别名	长春胺 \| 太司尼克酸 \| 长春花素 \| 长春花胺 \| 长春蔓胺
英文别名	HMS2095H04 \| C09251 \| DTXSID9040134 \| Methyl vincaminate \| Oxybral \| Tox21_111342_1 \| Tripervan \| Vincamina [DCIT] \| VINCAMINE [MART.] \| Anasclerol (base) \| Equipur \| KS-5179 \| Vincamina \| Cetal retard \| HMS3712H04 \| methyl (15S,17S,19S)-15-ethyl-17-hydro
规格或纯度	98%
英文名称	Vincamine
储存温度	2-8°C储存
运输条件	冰袋运输
产品介绍	Vincamine 是从马达加斯加长春花中提取的一种单萜类吲哚生物碱。Vincamine 可以作为一种外周血管扩张剂 (Vasodilator)，对脑微血管循环有选择性的血管调节作用。Vincamine 是一种 GPR40 激动剂，通过改善 β 细胞功能障碍和促进葡萄糖刺激型胰岛素分泌 (GSIS) 发挥 β 细胞保护作用。Vincamine 可改善体内葡萄糖稳态，对 2 型糖尿病 (T2DM) 的研究具有潜力。 Vincamine is a monoterpenoid indole alkaloid extracted from the Madagascar periwinkle. Vincamine is a peripheral vasodilator and exerts a selective vasoregulator action on the brain microcapilar circulation. Vincamine is a GPR40 agonist and acts as a β-cell protector by ameliorating β-cell dysfunction and promoting glucose-stimulated insulin secretion (GSIS). Vincamine improves glucose homeostasis in vivo, and has the potential for the type 2 diabetes mellitus (T2DM) research.

产品属性

ALogP	2.9

名称和标识符

EC号	216-576-3
IUPAC Name	methyl (15S,17S,19S)-15-ethyl-17-hydroxy-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraene-17-carboxylate
INCHI	InChI=1S/C21H26N2O3/c1-3-20-10-6-11-22-12-9-15-14-7-4-5-8-16(14)23(17(15)18(20)22)21(25,13-20)19(24)26-2/h4-5,7-8,18,25H,3,6,9-13H2,1-2H3/t18-,20+,21+/m1/s1
InChi Key	RXPRRQLKFXBCSJ-GIVPXCGWSA-N
Canonical SMILES	CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(C2)(C(=O)OC)O
Isomeric SMILES	CC[C@@]12CCCN3[C@@H]1C4=C(CC3)C5=CC=CC=C5N4[C@](C2)(C(=O)OC)O
WGK Germany	3
RTECS	YY8575000
PubChem CID	15376
分子量	354.44
Beilstein号	25(3/4)1252

数据库链接

PubChem CID	15376
ChEBI	CHEBI:9985
Wikipedia	Vincamine
ChEMBL Ligand	CHEMBL1165342
CAS Registry No.	1617-90-9
DrugCentral Ligand	3643
GPCRdb Ligand	vincamine

化学和物理性质

密度	1.36
比旋光度	43° (C=1,Pyridine)
熔点	232°C

安全和危险性（GHS）

象形图	Harmful
信号词	Warning
危险声明	H302: Harmful if swallowed
预防措施声明	P501,P264,P270,P330,P301+P317
WGK Germany	3
RTECS	YY8575000
Merck Index	9983
个人防护装备	dust mask type N95 (US),Eyeshields,Gloves

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参考文献

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长春胺

库存信息

库存信息

库存信息

库存信息

基本描述

产品属性

名称和标识符

数据库链接

化学和物理性质

安全和危险性（GHS）

质检证书(COA)

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