Rat anti Mouse PD-L2/CD273 Antibody, Monoclonal (TY25), could be used for in vivo PD-L2 blockade, in vitro PD-L2 blockade, IHC, Flow and so on. Application: in vivo PD-L2 blockade: Use at an assay dependent concentration. in vitro PD-L2 blockade: Use at an assay dependent concentration. IHC: Use at an assay dependent concentration. Flow: Use at an assay dependent concentration. Protein Function Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
PD-L2/CD273 Rat mAb (Ab121050) - Flow Cytometry Two-color flow cytometric analysis of PD-L2/CD273 expression on mouse splenocytes. C57BL/6 mouse spleen cells were unstimulated (left) or 10 ng/mL mouse GM-CSF protein (rp154039) stimulated (right), and stained with CD11c Armenian Hamster mAb (APC) (Ab178872) and PD-L2/CD273 Rat mAb (Ab121050) at 0.5 μg/mL. Two-color flow cytometric dot plots showing the correlated expression of CD11C versus PD-L2/CD273 (or Isotype control staining) were derived from gated events with the forward and side light-scatter characteristics of viable mononuclear cells.
ZJ24F0910570
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