Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity).
Dephosphorylates LYN, and thereby modulates LYN activity.
宿主种属
大鼠(Rat)
特异性
Mouse CD45
种属反应性
小鼠(Mouse)
免疫原
Mouse thymus or spleen
阳性对照
Flow Cytometry: C57BL/6 splenocytes
偶联
Unconjugated
克隆类型
重组抗体
Format
Whole IgG
轻链亚型
kappa
纯化方法
Protein A purified
浓度
见COA
分子类型
抗体
产品线
生物产品
储存与运输
储存缓冲液
PBS, pH 7.4
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
Store at 4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
图片
Recombinant CD45 Antibody (Ab210980) - Flow Cytometry Flow Cytometry analysis of mouse splenocytes cells labelling CD45 with Recombinant CD45 Antibody (Ab210980) conjugated with biotin (right panel) at 0.2 μg/mL for 1 hour at 4°C, compared with Rat IgG Isotype Control Antibody (Biotin) (Ab180310) (left panel) and detected with SA-PE (rp156150).
Recombinant CD45 Antibody (Ab210980) - Flow Cytometry Flow Cytometry analysis of mouse splenocytes cells labelling CD45 (red) with Recombinant CD45 Antibody (Ab210980) conjugated with biotin at 0.2 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Rat IgG Isotype Control Antibody (Biotin) (Ab180310). Black - Unlabelled control, cells without incubation with primary antibody.
Recombinant CD45 Antibody (Ab210980) - SEC The purity of Recombinant CD45 Antibody (Ab210980) is more than 95% verified by HPLC.
危险品化学品经营许可证（带存储）