Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4.
Also acts as an integrin ligand which is required for FGF2 signaling.
Binds to integrin ITGAV:ITGB3.
Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration.
Functions as a potent mitogen in vitro.
Can induce angiogenesis.
Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation.
FGF2 Mouse mAb (Ab223235) - Western Blot All lanes: FGF2 Mouse Antibody (Ab223235) at 1/2000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab179001) at 1/20000 dilution
Predicted band size: 31 kDa Observed band size: 18, 24, 26 kDa Exposure time: 30.0 s