药靶抗体

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11 项目

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  1. 曲妥珠单抗
      规格或纯度 :
    • ≥95%
    • ~21mg/ml(in buffer,pH6.0)
    关联靶标: ERBB2
    CAS号 : 180288-69-1        Compound CID : 135518164
    分子式: C6470H10012N1726O2013S42        分子量: 145531.50
    IUPAC Name: 2,8-diamino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
    SMILES: C(C1C(C(C(O1)N2C3=C(C(=O)NC(=N3)N)N=C2N)O)O)O
    InChIKey: FNXPTCITVCRFRK-UMMCILCDSA-N
    InChI: InChI=1S/C10H14N6O5/c11-9-14-6-3(7(20)15-9)13-10(12)16(6)8-5(19)4(18)2(1-17)21-8/h2,4-5,8,17-19H,1H2,(H2,12,13)(H3,11,14,15,20)/t2-,4-,5-,8-/m1/s1
  2. Pertuzumab (anti-HER2)
      应用:
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    关联靶标: CYP1A2 ERBB2 ADRB2
    • 简短描述: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    • 种属反应性: 人(Human), 大鼠(Rat), 小鼠(Mouse)
    • 亚型: Human IgG1
    • 宿主种属: 人(Human)
    • 偶联: Unconjugated
    CAS号 : 380610-27-5        Compound CID : 5484725
    IUPAC Name: (2R,3S)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]-3-(propan-2-ylamino)butan-2-ol
    SMILES: CC1=C2CCCC2=C(C=C1)OCC(C(C)NC(C)C)O
    InChIKey: VFIDUCMKNJIJTO-BBRMVZONSA-N
    InChI: InChI=1S/C17H27NO2/c1-11(2)18-13(4)16(19)10-20-17-9-8-12(3)14-6-5-7-15(14)17/h8-9,11,13,16,18-19H,5-7,10H2,1-4H3/t13-,16-/m0/s1
  3. Trastuzumab (anti-HER2)
      应用:
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    关联靶标: ERBB2
    • 简短描述: Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    • 种属反应性: 人(Human), 小鼠(Mouse)
    • 亚型: Human IgG1
    • 宿主种属: 人(Human)
    • 偶联: Unconjugated
    CAS号 : 180288-69-1        Compound CID : 135518164
    分子式: C6470H10012N1726O2013S42        分子量: 145531.50
    IUPAC Name: 2,8-diamino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
    SMILES: C(C1C(C(C(O1)N2C3=C(C(=O)NC(=N3)N)N=C2N)O)O)O
    InChIKey: FNXPTCITVCRFRK-UMMCILCDSA-N
    InChI: InChI=1S/C10H14N6O5/c11-9-14-6-3(7(20)15-9)13-10(12)16(6)8-5(19)4(18)2(1-17)21-8/h2,4-5,8,17-19H,1H2,(H2,12,13)(H3,11,14,15,20)/t2-,4-,5-,8-/m1/s1
  4. Trastuzumab emtansine (anti-ERBB2)
      应用:
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    关联靶标: ERBB2
    • 简短描述: Purity≥90% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Conjugated (SMCC-DM1)
    • 种属反应性: 人(Human)
    • 亚型: Human IgG1
    • 宿主种属: 人(Human)
    • 偶联: SMCC-DM1
    CAS号 : 1018448-65-1        Compound CID : 163341910
    SMILES: C[C@@H]1[C@@H]2C[C@]([C@@H](/C=C\C=C(/CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)C[C@@H]([C@@]4([C@H]1O4)C)OC(=O)[C@H](C)N(C)C(=O)CCSC5CC(=O)N(C5=O)CC6CCC(CC6)C(=O)N)C)\C)OC)(NC(=O)O2)O
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