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神经信号
神经信号参与中枢神经系统的结构、功能、遗传和生理的调节。神经元合成/导入神经递质，并将其储存在突触前囊泡中。突触前神经元释放的小泡，进而传递神经冲动。常见的神经递质有γ氨基丁酸（GABA）、谷氨酸、血清素、多巴胺等。在神经信号通路中，这些神经递质的功能障碍可能多种神经系统疾病，如慢性疼痛、神经退行性疾病、失眠、精神障碍（精神分裂症、双相情感障碍、抑郁症和成瘾）等。
神经信号通路转导过程
当受到来自环境或其他神经元的信号刺激时，神经递质受体通过G蛋白偶联信号通路和G蛋白非依赖机制激活下游细胞内信号通路：包括cAMP/PKA, PI3K/AKT, 磷脂酶A2（PLA2）, 磷脂酶C（PLC）信号通路等。例如，多巴胺受体通过cAMP激活PKA等信号分子，通过CREB和其他转录因子的作用调控基因表达。其他神经递质如NMDAR或AMPAR与控制Ca2+和Na+流量的离子通道有关，这样就能在突触后神经元中传递动作电位。
神经信号通路图
产品列表
*肾上腺素能受体
| 项目号 | 产品名称 | 规格 | CAS | 包装 | 靶点 | IC50 | pKi | Ki | Kd | EC50 | ED50 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| D129796 | 甲磺酸多沙唑嗪 | ≥99% | 77883-43-3 | 50mg,100mg,250mg,1g,5g,25g,100g | |||||||
| I129899 | Ivabradine HCl | ≥98% | 148849-67-6 | 250mg,1g,5g | |||||||
| C129903 | Cisatracurium Besylate | ≥98% | 96946-42-8 | 1g | |||||||
| A124739 | Asenapine maleate | ≥98% (HPLC) | 85650-56-2 | 10mg,50mg,250mg,1g | |||||||
| C141489 | 卡拉洛尔 | 98% | 57775-29-8 | 250mg,1g | |||||||
| C120231 | 卡拉洛尔 | 分析标准品 | 57775-29-8 | 10mg | |||||||
| A129804 | Alfuzosin hydrochloride | ≥98% | 81403-68-1 | 50mg,100mg,250mg,1g | |||||||
| S126595 | Silodosin | ≥99% | 160970-54-7 | 5mg,25mg,100mg,250mg,1g | |||||||
| N129836 | Nebivolol hydrochloride | ≥97% | 152520-56-4 | 10mg,20mg,100mg,1g,5g | β1-adrenoceptor | 0.8 nM | |||||
| B129688 | BMY 7378 dihydrochloride | ≥98% | 21102-95-4 | 10mg,50mg,100mg | α2C-adrenoceptor | 6.54 | |||||
| α1D-adrenoceptor | 8.2 | ||||||||||
| 5-HT1A | 8.3 | ||||||||||
| P160142 | Prazosin Hydrochloride | ≥98.0% | 19237-84-4 | 50mg,250mg,1g | |||||||
| P123277 | 甲磺酸酚妥拉明 | ≥98.0%(TLC) | 65-28-1 | 100mg,500mg,5g | α-adrenergic receptor | 0.1 μM | |||||
| M111944 | 酒石酸美托洛尔 | 分析标准品 | 56392-17-7 | 1g | β-adrenergic receptor | 42 ng/mL | |||||
| M111945 | 酒石酸美托洛尔 | 98% | 56392-17-7 | 5g | β-adrenergic receptor | 42 ng/mL | |||||
| T129895 | Terazosin hydrochloride Dihydrate | ≥98% | 70024-40-7 | 100mg,5g,25g | α-adrenergic receptor | ||||||
| M129850 | Maprotiline HCl | ≥99%(HPLC) | 10347-81-6 | 1g,5g,25g | |||||||
| C123267 | Carvedilol | ≥98%(HPLC) | 72956-09-3 | 1g,5g,25g | β/α-1受体 | ||||||
| N129805 | Naftopidil | ≥98.0% | 57149-07-2 | 5g,25g,500g | α受体 | 58.3 nM | |||||
| P129843 | Phenoxybenzamine HCl | ≥98% | 63-92-3 | 1g,5g,25g | α受体 | 550 nM | |||||
| A129820 | Acebutolol HCl | ≥99% | 34381-68-5 | 250mg | β-adrenergic receptor | ||||||
| B129336 | Buflomedil HCl | ≥98% | 35543-24-9 | 1g,5g,25g,100g,500g | α-adrenergic receptor | ||||||
| C134671 | cis-(Z)-Flupentixol Dihydrochloride | ≥98% (HPLC) | 51529-01-2 | 250mg | D1多巴胺受体 | ||||||
| D2多巴胺受体 | |||||||||||
| A132124 | 阿普洛尔 盐酸盐 | ≥99% | 13707-88-5 | 50mg,250mg | α-adrenergic receptor | ||||||
| M171294 | Moxisylyte hydrochloride | >99% (TLC) | 964-52-3 | 25g | |||||||
| A151072 | 阿替美唑盐酸盐 | >98.0%(HPLC)(T) | 104075-48-1 | 25mg,100mg,250mg,1g | α2 adrenergic receptor | ||||||
| A132977 | Atipamezole | ≥98% (HPLC) | 104054-27-5 | 5mg,25mg,100mg,1g | α2 adrenergic receptor | ||||||
| P160771 | 吡贝地尔 | >98.0%(GC)(T) | 3605-01-4 | 200mg,1g | α2A | 7.1 | |||||
| α2C | 7.2 | ||||||||||
| T102080 | 盐酸坦索罗辛 | 98% | 106463-17-6 | 100mg,500mg,1g | α1A | ||||||
| T136685 | Terazosin Hydrochloride | >98.0%(HPLC) | 63074-08-8 | 50mg,250mg,1g | α1-AR | ||||||
| D193380 | 盐酸贝凡洛尔 | 98% | 42864-78-8 | 250mg,1g,5g | |||||||
| N159472 | N-(2-氯乙基)二苄胺盐酸盐 | >98.0%(N) | 55-43-6 | 25g,500g | |||||||
| B129900 | Betaxolol | ≥98% | 63659-18-7 | 10mg,50mg,250mg | β-adrenergic receptor | ||||||
| A124776 | 阿替洛尔 | ≥98%,powder | 29122-68-7 | 1g,5g,25g,100g | β1 receptor | 0.25 μM | |||||
| β2 receptor | 1 μM | ||||||||||
| Y111137 | 盐酸育亨宾 | 99% | 65-19-0 | 1g,5g,25g | |||||||
| Y111138 | 盐酸育亨宾 | 分析标准品,≥99% | 65-19-0 | 20mg | |||||||
| Y140628 | 盐酸育亨宾 | 97% | 65-19-0 | 1g,5g,25g | |||||||
| L133648 | Labetalol HCl | 98% | 32780-64-6 | 50mg,250mg,1g | α1-adrenergic receptor | ||||||
| β-adrenergic receptor | |||||||||||
| M126688 | Mirabegron | ≥99% | 223673-61-8 | 5mg,10mg,50mg,250mg,1g | β3-adrenoceptor | 22.4 nM | |||||
| X113956 | 盐酸甲苯噻嗪 | 98% | 23076-35-9 | 1g,5g,25g,100g | |||||||
| X113957 | 盐酸甲苯噻嗪 | 分析标准品 | 23076-35-9 | 100mg | |||||||
| D194797 | 盐酸阿可乐定(曾用名:盐酸安普乐定) | 97% | 73218-79-8 | 25mg,100mg,250mg,1g,5g | |||||||
| I134069 | 异舒普林 盐酸盐 | 分析标准品 | 579-56-6 | 1g,5g | |||||||
| I157518 | 茚达特罗马来酸盐 | >98.0%(HPLC) | 753498-25-8 | 20mg,25mg,50mg,100mg,1g | β1-adrenoceptor | 7.36 | |||||
| β2-adrenoceptor | 5.48 | ||||||||||
| I129810 | 盐酸异丙肾上腺素 | ≥99% | 51-30-9 | 5g,25g,100g | β-adrenergic receptor | ||||||
| F129812 | Formoterol Hemifumarate | ≥99% | 43229-80-7 | 10mg,50mg | β2-adrenergic receptor | ||||||
| E129809 | 酒石酸肾上腺素 | ≥98% | 51-42-3 | 1g,5g,25g | |||||||
| C102161 | 盐酸可乐定 | 98% | 4205-91-8 | 250mg,1g,5g,100g | α2-adrenergic receptor | 0.02±0.01 mg/kg | |||||
| D129407 | Droxidopa | ≥98% | 23651-95-8 | 50mg,250mg | Adrenergic Receptor | ||||||
| D129818 | Dexmedetomidine | ≥98% | 113775-47-6 | 50mg,250mg | α2 receptor | 1.08 nM | |||||
| P106007 | 盐酸去氧肾上腺素 | 99% | 61-76-7 | 5g,10g,25g,50g,100g | α1-adrenergic receptor | ||||||
| G156852 | 氯苄氨胍醋酸盐 | >98.0%(HPLC) | 23256-50-0 | 200mg,1g,5g | α2a-adrenergic receptor | ||||||
| α2b-adrenergic receptor | |||||||||||
| α2c-adrenergic receptor | |||||||||||
| N113459 | Naphazoline hydrochloride | 99% | 550-99-2 | 5g,25g,100g,500g | Adrenergic Receptor | ||||||
| R124692 | 利托君盐酸盐 | ≥98% | 23239-51-2 | 250mg,1g,5g | β2-adrenergic receptor | ||||||
| D129813 | Dexmedetomidine HCl | ≥98% | 145108-58-3 | 5mg,10mg,50mg,100mg | α-2 adrenoceptor | ||||||
| M129911 | Medetomidine HCl | ≥99% | 86347-15-1 | 10mg,25mg,50mg,100mg | α2-adrenoceptor | 1.08 nM | |||||
| T101308 | 替扎尼定 | 98% | 64461-82-1 | 5g,25g | α2-adrenergic receptor | ||||||
| D129815 | Detomidine HCl | ≥98% | 90038-01-0 | 50mg,250mg,1g | Adrenergic Receptor | ||||||
| S129883 | Scopine | ≥98% | 498-45-3 | 25mg,100mg,200mg,500mg | α1-adrenergic receptor | ||||||
| N107258 | 重酒石酸去甲肾上腺素一水合物 | ≥98%（HPLC),USP | 108341-18-0 | 250mg,1g,5g,25g | α-adrenergic receptor | ||||||
| X139232 | 赛拉嗪 | ≥98.0%(HPLC) | 7361-61-7 | 1g,5g,10g,25g | α-2 adrenergic receptor | ||||||
| X129373 | Xylometazoline HCl | ≥98.0%(HPLC) | 1218-35-5 | 1g,5g,25g,100g | α-adrenoceptor | 4 μM | |||||
| A140618 | 双甲脒 | 97% | 33089-61-1 | 1g,5g | α2 adrenergic receptor | ||||||
| G133358 | Guanfacine hydrochloride | ≥98%(HPLC) | 29110-48-3 | 10mg,50mg,100mg,250mg | α2A-adrenoceptor | ||||||
| I125935 | Indacaterol | ≥99% | 312753-06-3 | 50mg,250mg | β1-adrenoceptor | 7.36 | |||||
| β2-adrenoceptor | 5.48 | ||||||||||
| B134443 | Bambuterol Hydrochloride | ≥98% (HPLC) | 81732-46-9 | 1g,5g | β-adrenergic receptor | ||||||
| D134211 | DL-去甲肾上腺素 盐酸盐 | 97% | 55-27-6 | 1g,5g,25g | |||||||
| S107339 | 辛弗林 | 分析标准品,≥98% | 94-07-5 | 20mg | Adrenergic Receptor | ||||||
| S107340 | 辛弗林 | 98% | 94-07-5 | 5g,25g | Adrenergic Receptor | ||||||
| N109573 | L-去甲肾上腺素 | 98% | 51-41-2 | 250mg,1g | α1 adrenoceptor | 330 nM | |||||
| α2A adrenoceptor | 56 nM | ||||||||||
| β1 adrenoceptor | 740 nM | ||||||||||
| B136672 | Brimonidine | >98.0%(HPLC) | 59803-98-4 | 250mg,1g,5g | |||||||
| D137302 | 双氢麦角胺甲磺酸盐 | >95.0%(HPLC) | 6190-39-2 | 100mg,250mg,1g | |||||||
| D135863 | 双氢麦角胺甲磺酸盐 | 药典级 | 6190-39-2 | 250mg | |||||||
| D129628 | 醋酸去氧皮质酮 | ≥99% | 56-47-3 | 250mg,1g,5g |
*AChR
| 项目号 | 产品名称 | 规格 | CAS | 包装 | 靶点 | IC50 | Ki | Kd | Kb | pKi |
|---|---|---|---|---|---|---|---|---|---|---|
| D129948 | Donepezil HCl | ≥98% | 120011-70-3 | 250mg,1g,5g,25g,100g | bAChE | 8.12 nM | ||||
| hAChE | 11.6 nM | |||||||||
| H107335 | 石杉碱甲 | 分析标准品 | 102518-79-6 | 25mg | AChE | 7 nM | ||||
| H107336 | 石杉碱甲 | 98% | 102518-79-6 | 100mg | AChE | 7 nM | ||||
| D109823 | 甲基硫酸新斯的明 | 98% | 51-60-5 | 1g,5g,25g | AChE | |||||
| B129446 | Amfebutamone (Bupropion) HCl | ≥98% (HPLC) | 31677-93-7 | 250mg,1g,5g | AChR | 6.5 μM | ||||
| Dopamine receptor | 3.4 μM | |||||||||
| G111443 | 氢溴酸加兰他敏 | 98% | 1953-04-4 | 100mg,500mg,1g | AChE | 0.35 μM | ||||
| R129955 | Rocuronium Bromide | ≥98% | 119302-91-9 | 10mg,50mg,100mg,250mg,1g | AChR | |||||
| O129950 | Otilonium Bromide | ≥98% | 26095-59-0 | 5g,25g | mAChR | |||||
| G129967 | 加拉碘铵 | ≥98% | 65-29-2 | 1g,5g,25g | AChR | 68.0±8.4 μM | ||||
| P160474 | 溴吡斯的明 | >98.0%(HPLC)(T) | 101-26-8 | 5g,25g | AChR | |||||
| R129987 | Rivastigmine Tartrate | ≥98% | 129101-54-8 | 250mg,1g,5g | AChR | 5.5 μM | ||||
| I129957 | Irsogladine | ≥98% | 57381-26-7 | 1g,5g | AChR | |||||
| mAChR | ||||||||||
| PDE | ||||||||||
| N159835 | 溴化新斯的明 | >99.0%(T) | 114-80-7 | 1g,5g,25g | AChR | |||||
| V107317 | 长春质碱 | 分析标准品,≥98% | 2468-21-5 | 20mg | nicotinic receptor | 59.6µM | ||||
| D101734 | 多萘哌齐碱 | 98% | 120014-06-4 | 25mg,100mg | AChE | 6.7 nM | ||||
| P113899 | 盐酸普鲁卡因 | 99% | 51-05-8 | 25g,100g,500g | 钠离子通道 | 60 μM | ||||
| nAChR | 45.5 μM | |||||||||
| NMDA受体 | 0.296 mM | |||||||||
| 5-HT3 | 1.7 μM | |||||||||
| P113900 | 盐酸普鲁卡因 | 分析标准品 | 51-05-8 | 250mg | 钠离子通道 | 60 μM | ||||
| nAChR | 45.5 μM | |||||||||
| NMDA受体 | 0.296 mM | |||||||||
| 5-HT3 | 1.7 μM | |||||||||
| E131855 | Edrophonium Chloride | ≥98% | 116-38-1 | 50mg | ||||||
| A129655 | 苯磺酸阿曲库胺 | ≥98% | 64228-81-5 | 250mg,1g,5g | ||||||
| L111134 | 马钱子苷 | 98% | 18524-94-2 | 10mg,50mg,100mg | AChE | 3.95 μM | ||||
| BChE | 33.02 μM | |||||||||
| BACE1 | 47.97 μM | |||||||||
| I132366 | 依托必利盐酸盐 | ≥98% (HPLC) | 122892-31-3 | 1g,5g,25g,100g,500g | AChE | 2.04 ± 0.27 μM | ||||
| H105566 | 苄索氯铵 | 0.97 | 121-54-0 | 25g,100g,250g,500g,2.5kg | α4β2 nAChRs | 49 nM | ||||
| α7 nAChRs | 122 nM | |||||||||
| H165301 | 苄索氯铵 | 分析标准品 | 121-54-0 | 1g | α4β2 nAChRs | 49 nM | ||||
| α7 nAChRs | 122 nM | |||||||||
| A135769 | 9-氨基-1,2,3,4-四氢吖啶盐酸盐水合物 | ≥99% | 206658-92-6 | 1g,5g | HNMT | |||||
| cholinesterase | ||||||||||
| P129078 | 盐酸哌仑西平 | ≥99.0% | 29868-97-1 | 250mg,1g,5g | ||||||
| P111383 | 黄藤素 | 分析标准品,≥97% | 3486-67-7 | 250mg | AChE | 0.51 μM | ||||
| P111384 | 黄藤素 | 97% | 3486-67-7 | 5g,25g | BChE | 6.84 μM | ||||
| J115851 | 盐酸药根碱 | 分析标准品,≥98% | 6681-15-8 | 10mg,50mg | AChE | 872 nM | ||||
| J141082 | 盐酸药根碱 | ≥90%(HPLC) | 6681-15-8 | 10mg | AChE | 872 nM | ||||
| J101538 | 药根碱 | >97%(HPLC) | 3621-38-3 | 25mg,100mg | AChE | 872 nM | ||||
| V100993 | Vinblastine sulfate | ≥97%(HPLC) | 143-67-9 | 50mg,250mg | nAChR | 8.9 μM | ||||
| V100992 | 硫酸长春碱 | ≥97%(HPLC) | 143-67-9 | 10mg | nAChR | 8.9 μM | ||||
| R125607 | Rivastigmine | ≥99% | 123441-03-2 | 25mg,100mg,500mg | 胆碱酯酶 | 5.5 μM | ||||
| 乙酰胆碱酯酶 | 4.15 µM | |||||||||
| 丁酰胆碱酯酶 | 37 nM | |||||||||
| H156997 | 骆驼蓬灵 | >98.0%(HPLC) | 304-21-2 | 1g,5g | AChR | |||||
| P196127 | 苦玄参苷 IA | 分析对照品 | 97230-47-2 | 20mg | ||||||
| B136646 | 三己芬迪盐酸盐 | 98% | 52-49-3 | 1g,5g,25g | ||||||
| E107840 | 乙基(三苯基膦)乙酸酯 | 98% | 1099-45-2 | 5g,25g,100g,500g | AChE | |||||
| BChE | ||||||||||
| A129364 | Adiphenine HCl | ≥98% | 50-42-0 | 10g,50g | 烟碱受体 | 15 µM | ||||
| G125955 | Galanthamine | ≥98 % | 357-70-0 | 100mg,500mg | acetylcholinesterase | 0.35 μM | ||||
| M158298 | 1-甲基吡啶-2-醛肟氯盐 | >98.0%(HPLC)(T) | 51-15-0 | 5g,10g,25g,100g,500g | AChE | |||||
| T129932 | Tiotropium Bromide hydrate | ≥99% | 139404-48-1 | 5mg,25mg,50mg,100mg | AChR | |||||
| P129976 | Pancuronium dibromide | ≥99% | 15500-66-0 | 25mg,100mg | AChR | |||||
| T129938 | Tolterodine tartrate | ≥98% | 124937-52-6 | 10mg,25mg,50mg,100mg,250mg,1g | AChR | |||||
| F129939 | Fesoterodine Fumarate | ≥99% | 286930-03-8 | 2mg,5mg,10mg,50mg | AChR | |||||
| O129945 | Oxybutynin | ≥98% | 5633-20-5 | 1g,5g | AChR | |||||
| S129952 | Solifenacin succinate | ≥99% | 242478-38-2 | 10mg,25mg,50mg,100mg,250mg,1g,5g | mAChR | |||||
| T129936 | Trospium chloride | ≥99% | 10405-02-4 | 25mg,100mg,200mg,500mg,1g | ||||||
| A109524 | Atropine sulfate monohydrate | 98.5% | 5908-99-6 | 5g,25g | mAChR | 2.5 nM | ||||
| S129958 | Methscopolamine Bromide | ≥98% | 155-41-9 | 1g | mAChR | |||||
| H129983 | 5-hydroxymethyl Tolterodine (PNU 200577, 5-HMT, 5-HM) | ≥99% | 207679-81-0 | 5mg,10mg,50mg | mAChR | 0.84 nM | ||||
| D129992 | Darifenacin HBr | ≥98% | 133099-07-7 | 10mg,50mg,250mg,1g,5g | M3 mAChR | 8.9 | ||||
| C124579 | 克利溴铵 | 分析标准品 | 3485-62-9 | 1g | ||||||
| F120768 | 盐酸黄酮哌酯 | 98% | 3717-88-2 | 5g,25g,100g | mAChR | 12.2 μM | ||||
| O129984 | Orphenadrine Citrate | ≥95% | 4682-36-4 | 5g,25g | AChR | |||||
| P129500 | Pentoxyverine Citrate | ≥96% | 23142-01-0 | 100mg,250mg,1g,5g,25g | mAChR | |||||
| B139017 | 盐酸苯乃嗪 | ≥98% | 57-37-4 | 1g,5g,25g | Muscarinic receptor | |||||
| H170991 | 溴化六甲铵 | - | 55-97-0 | 5g,25g,100g | AChR | |||||
| G124783 | 甘罗溴铵 | ≥98% (HPLC) | 596-51-0 | 25mg,100mg,250mg,500mg,1g | Muscarinic receptor | |||||
| P170634 | 溴丙胺太林 | 97% (TLC) | 50-34-0 | 5g | ||||||
| P170634 | 顺-2,6-二甲基哌啶 | 97% | 504-03-0 | 5ml,25ml,100ml | ||||||
| T123278 | 托吡卡胺 | ≥99.0% | 1508-75-4 | 1g,5g,10g | M4 mAChR | 8 nM | ||||
| C140843 | Cevimeline hydrochloride hemihydrate | ≥95% (HPLC) | 153504-70-2 | 5mg,25mg,100mg | ||||||
| V120183 | Varenicline tartrate | 98% | 375815-87-5 | 5mg,25mg,50mg,250mg,1g | AChR | |||||
| B153105 | Bethanechol Chloride | >98.0%(T) | 590-63-6 | 5g,25g,100g | mAChR | |||||
| A107392 | 氢溴酸丙胺 | 分析标准品 | 300-08-3 | 50mg,250mg | mAChR | |||||
| A107393 | 氢溴酸丙胺 | 98% | 300-08-3 | 1g,5g,25g,100g | mAChR | |||||
| P129614 | 盐酸毛果芸香碱 | ≥99% | 54-71-7 | 50mg,250mg,1g,5g | mAChR | |||||
| S161137 | 氯化琥珀酰胆碱二水合物 | >98.0%(T) | 6101-15-1 | 5g,25g | nAChR | |||||
| N135540 | Nitenpyram | 分析标准品 | 150824-47-8 | 100mg | AchR | |||||
| C107704 | 金雀花碱 | 分析标准品 | 485-35-8 | 20mg | nAChR | |||||
| C107705 | 金雀花碱 | 98% | 485-35-8 | 25mg,100mg,500mg,1g | nAChR | |||||
| C108896 | 氯化胆碱 | 98% | 67-48-1 | 25g,100g,500g,2.5kg | ||||||
| C108897 | 氯化胆碱 | 用于细胞和昆虫细胞培养,>98% | 67-48-1 | 100g,500g,1kg | ||||||
| C108898 | 氯化胆碱 | 99% | 67-48-1 | 25g,100g | ||||||
| D154687 | 溴化十烃季胺 | >98.0%(T) | 541-22-0 | 5g,25g | nAChR | |||||
| O135659 | O-Acetyl-β-methylcholine Chloride | ≥98.0% | 62-51-1 | 25g,100g,500g | muscarinic receptor | |||||
| A111014 | 氯化乙酰胆碱 | 99% | 60-31-1 | 5g,25g,100g | AChR | |||||
| A111015 | 氯化乙酰胆碱 | for cell culture,≥99% | 60-31-1 | 25g,100g | AChR | |||||
| A111033 | 碘化乙酰胆碱 | 98% | 2260-50-6 | 5g,25g | ||||||
| B169694 | BQCA | 98% (HPLC) | 338747-41-4 | 10mg,50mg | mAChR | |||||
| P125212 | PNU-120596 | ≥98% (HPLC) | 501925-31-1 | 10mg,50mg | ||||||
| V129458 | Vecuronium Bromide | ≥99% | 50700-72-6 | 25mg,100mg,250mg,1g,5g |
*组胺受体
| 项目号 | 产品名称 | 规格 | CAS | 包装 | 靶点 | IC50 | Ki |
|---|---|---|---|---|---|---|---|
| C115479 | Cetirizine dihydrochloride | 98% | 83881-52-1 | 1g,5g,25g,100g | Histamine receptor | ||
| F129253 | Fexofenadine HCl | ≥98% | 153439-40-8 | 10mg.50mg,1g,5g | Histamine H1 receptor | 246 nM | |
| E129640 | Epinastine HCl | ≥99% | 108929-04-0 | 50mg,250mg,1g,5g,25g | Histamine receptor | ||
| O159894 | Olopatadine Hydrochloride | >98.0%(HPLC) | 140462-76-6 | 250mg,1g | Histamine receptor | ||
| A124055 | 安他唑啉 盐酸盐 | 98% | 2508-72-7 | 1g,5g,25g,100g | |||
| K124652 | 酮替芬延胡索酸 | 99% | 34580-14-8 | 100mg,250mg,1g,5g,25g | Histamine H1 receptor | ||
| A129250 | Azatadine dimaleate | ≥98% | 3978-86-7 | 10mg,50mg,250mg,1g | Histamine receptor | 6.5 nM | |
| Cholinergic | 10 nM | ||||||
| H107699 | 橙皮素 | 分析标准品,≥98% | 520-33-2 | 20mg | Histamine receptor | ||
| H107700 | 橙皮素 | 97% | 520-33-2 | 1g,5g,25g,100g | Histamine receptor | ||
| C136571 | CarbinoxamineMaleateSalt | - | 3505-38-2 | 5g,10g,25g | Histamine H1 receptor | ||
| D129627 | Doxylamine Succinate | ≥99% | 562-10-7 | 1g,5g,10g,25g,50g | Histamine H1 receptor | ||
| B102783 | 盐酸倍他司汀 | 99% | 5579-84-0 | 1g,5g,10g,25g,100g | Histamine H3 receptor | 1.9 μM | |
| C129211 | Clemastine Fumarate | ≥98% (HPLC) | 14976-57-9 | 100mg,250mg,500mg,1g | Histamine H1 receptor | 3 nM | |
| L129669 | Latrepirdine | ≥96% | 97657-92-6 | 5mg,10mg,50mg | histamine receptors | ||
| GluR | |||||||
| 5-HT receptors | |||||||
| L129223 | Loratadine | ≥98% | 79794-75-5 | 100mg,1g,5g,25g | B(0)AT2 | 4 μM | |
| H1 receptor | |||||||
| B129218 | Bepotastine Besilate | 98% | 190786-44-8 | 10mg,50mg,100mg,250mg,10g | Histamine H1 receptor | ||
| M129226 | Mianserin HCl | ≥98% | 21535-47-7 | 50mg,250mg,1g,5g | Histamine receptor | ||
| M157977 | 美喹他嗪 | >98.0%(GC) | 29216-28-2 | 100mg,250mg,1g | |||
| C125175 | Clemizole | ≥98% | 442-52-4 | 5mg,25mg,100mg | H1 receptor | ||
| TRPC5 | |||||||
| A129214 | Azelastine HCl | ≥98%(HPLC) | 79307-93-0 | 100mg,250mg,1g,5g,25g | Histamine receptor | ||
| R129213 | 盐酸雷尼替丁 | ≥98%(HPLC) | 66357-59-3 | 1g,5g,25g | Histamine H2 receptor | 3.3±1.4 μM | |
| D129201 | Diphenhydramine Hydrochloride | ≥98% (HPLC) | 147-24-0 | 5g,25g,100g,500g | Histamine H1 receptor | ||
| D155989 | Desloratadine | >98.0%(HPLC)(T) | 100643-71-8 | 100mg,250mg,1g,5g,25g | Histamine H1 receptor | 51 nM | |
| C129233 | 马来酸氯苯那敏 | ≥99% | 113-92-8 | 5g,25g,100g,500g | Histamine H1 receptor | 12 nM | |
| M129292 | Meclizine 2HCl | ≥98% | 1104-22-9 | 250mg,1g,5g,25g | Histamine H1 receptor | ||
| M129245 | Mizolastine | ≥98% | 108612-45-9 | 1g,5g | Histamine H1 receptor | 47 nM | |
| C102301 | Cimetidine | 99% | 51481-61-9 | 5g,25g,100g | Histamine H2 receptor | ||
| L129237 | Lafutidine | ≥99% | 118288-08-7 | 10mg,50mg,250mg | Histamine H2 receptor | ||
| N129229 | Nizatidine | ≥98% | 76963-41-2 | 5g,25g | Histamine H2 receptor | 0.9 nM | |
| H168667 | 羟嗪 二盐酸盐 | 98% | 2192-20-3 | 10g | Histamine H1 receptor | 10 nM-19 nM | |
| B129275 | Brompheniramine hydrogen maleate | ≥98% | 980-71-2 | 50mg,250mg,1g,5g,25g | Histamine H1 receptor | ||
| J129258 | JNJ-7777120 | ≥98% (HPLC) | 459168-41-3 | 10mg,50mg | Histamine H4 receptor | 4.5 nM | |
| P129261 | Pemirolast potassium | ≥99% | 100299-08-9 | 10mg,50mg,250mg | Histamine H1 receptor | ||
| L124802 | 盐酸左旋西替利嗪 | ≥98% (HPLC) | 130018-87-0 | 1g,5g | Histamine H1 receptor | ||
| P129451 | Pheniramine Maleate | ≥99% | 132-20-7 | 1g,5g | |||
| C119225 | 咳平盐酸盐 | 分析标准品 | 14984-68-0 | 5g,10g,25g | Histamine H2 receptor | 3.2 μM | |
| A151022 | 阿伐斯汀 | >98.0%(HPLC) | 87848-99-5 | 20mg,100mg | |||
| E134559 | 富马酸依美斯汀 | ≥98.0%(HPLC) | 87233-62-3 | 50mg,250mg,1g,5g | Histamine H1 receptor | ||
| F129242 | Famotidine | ≥99% | 76824-35-6 | 5g,25g | H2 receptor | ||
| P133927 | 盐酸异丙嗪 | >98.0%(HPLC) | 58-33-3 | 25g,100g | |||
| L129221 | Lidocaine | ≥99% | 137-58-6 | 5g,25g,100g | Histamine H1 receptor | >32 μM | |
| H111796 | 组胺 | 96% | 51-45-6 | 1g,5g | |||
| H110868 | 组胺二盐酸盐 | 98% | 56-92-8 | 5g,25g,100g | |||
| B152161 | 甲磺酸倍他司汀 | >99.0%(HPLC) | 54856-23-4 | 25g,100g,500g |
危险品化学品经营许可证（带存储）