计算溶液所需的质量、体积或浓度。
活性类型 | 活性值-log(M) | 作用机制 | 期刊 | 参考文献(PubMed IDs) |
---|
货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
---|---|---|---|---|
C409015-1ml |
1ml |
现货 ![]() |
|
英文别名 | CGP9555, CCl 4725 | (11β,16β)-21-chloro-9-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-pregna-1,4-diene-3,20-dione |
---|---|
规格或纯度 | Moligand™, 10mM in DMSO |
英文名称 | Clobetasol propionate |
生化机理 | 丙酸氯倍他索(CGP9555,CCl 4725)是一种抗炎皮质类固醇,用于治疗各种皮肤病。 |
储存温度 | -80℃储存 |
运输条件 | 超低温冰袋运输 |
作用类型 | 激动剂 |
作用机制 | 糖皮质激素受体激动剂 |
产品介绍 |
Information Clobetasol propionate Clobetasol propionate (CGP9555, CCl 4725) is an anti-inflammatory corticosteroid used to treat various skin disorders. In vivo
cell lines: Concentrations: Incubation Time: Powder Purity:≥99% |
ALogP | 3.958 |
---|---|
hba_count | 4 |
HBD Count | 1 |
Rotatable Bond | 5 |
分子类型 | 小分子 |
---|---|
Canonical SMILES | CCC(=O)OC1(C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC12C)C(=O)CCl |
分子量 | 466.97 |
Reaxy-Rn | 37811597 |
Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=37811597&ln= |
DMSO(mg / mL) Max Solubility | 93 |
---|---|
DMSO(mM) Max Solubility | 199.16 |
Water(mg / mL) Max Solubility | <1 |
Reaxy-Rn | 37811597 |
---|---|
Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=37811597&ln= |
Concentration(Compounding value) | 9-11(mmol/L) |
---|---|
Record the entire process by video | Conform |
1. Youfang Huang, Yanyun Li, Qing Luo, Xiaojia Huang. (2021) One-step preparation of functional groups-rich graphene oxide and carbon nanotubes nanocomposite for efficient magnetic solid phase extraction of glucocorticoids in environmental waters. CHEMICAL ENGINEERING JOURNAL, 406 (126785). [10.1016/j.cej.2020.126785] |
2. Guihua Gao, Sijia Li, Shuo Li, Yudan Wang, Pan Zhao, Xiangyu Zhang, Xiaohong Hou. (2018) A combination of computational−experimental study on metal-organic frameworks MIL-53(Al) as sorbent for simultaneous determination of estrogens and glucocorticoids in water and urine samples by dispersive micro-solid-phase extraction coupled to UPLC-MS/MS. TALANTA, 180 (358). [PMID:29332823] [10.1016/j.talanta.2017.12.071] |
1. Youfang Huang, Yanyun Li, Qing Luo, Xiaojia Huang. (2021) One-step preparation of functional groups-rich graphene oxide and carbon nanotubes nanocomposite for efficient magnetic solid phase extraction of glucocorticoids in environmental waters. CHEMICAL ENGINEERING JOURNAL, 406 (126785). [10.1016/j.cej.2020.126785] |
2. Guihua Gao, Sijia Li, Shuo Li, Yudan Wang, Pan Zhao, Xiangyu Zhang, Xiaohong Hou. (2018) A combination of computational−experimental study on metal-organic frameworks MIL-53(Al) as sorbent for simultaneous determination of estrogens and glucocorticoids in water and urine samples by dispersive micro-solid-phase extraction coupled to UPLC-MS/MS. TALANTA, 180 (358). [PMID:29332823] [10.1016/j.talanta.2017.12.071] |