| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| E409154-1ml |
1ml |
现货  |
|
| 英文别名 | 3-hydroxy-estra-1,3,5(10)-trien-17-one |
|---|---|
| 规格或纯度 | Moligand™, 10mM in DMSO |
| 英文名称 | Estrone |
| 生化机理 | 雌酮是一种雌激素。 |
| 储存温度 | -80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 产品介绍 |
溶于醇、丙酮、二氧六环、苯、氯仿、吡啶及氢氧化碱溶液，微溶于醚和植物油，几乎不溶于水,水中溶解度:0.03 g/L。 Estrone is an estrogenic hormone. Target: Estrogen Receptor/ERR Estrone (E1) is an estrogenic hormone secreted by the ovary as well as adipose tissue with the chemical name of 3-hydroxyestra-1,3,5(10)-triene-17-one and the chemical formula C18H22O2. Estrone is one of several natural estrogens, which also include estriol and estradiol. Estrone is the least abundant of the three hormones; estradiol is present almost always in the reproductive female body, and estriol is abundant primarily during pregnancy. Estrone is relevant to health and disease states because of its conversion to estrone sulfate, a long-lived derivative. Estrone sulfate acts as a reservoir that can be converted as needed to the more active estradiol. It is the predominant estrogen in postmenopausal women.该品是1号避孕药用的激素类药炔雌醇的中间体。 Information Estrone is an estrogenic hormone. In vivo
cell lines： Concentrations： Incubation Time： Powder Purity:≥98% |
| ALogP | 3.938 |
|---|---|
| hba_count | 1 |
| HBD Count | 1 |
| 分子类型 | 小分子 |
|---|---|
| Canonical SMILES | CC12CCC3C(CCC4=CC(=CC=C34)O)C1CCC2=O |
| 分子量 | 270.37 |
| Reaxy-Rn | 1915075 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1915075&ln= |
| 溶解性 | Solubility (25°C) In vitro DMSO: 31 mg/mL (198.37 mM); Water: 31 mg/mL (198.37 mM); Ethanol: 31 mg/mL (198.37 mM); |
|---|---|
| DMSO(mg / mL) Max Solubility | 54 |
| DMSO(mM) Max Solubility | 199.73 |
| Water(mg / mL) Max Solubility | <1 |
| Reaxy-Rn | 1915075 |
|---|---|
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1915075&ln= |
| Concentration(Compounding value) | 9.8-10.2(mmol/L) |
|---|---|
| Appearance(E409154) | Colorless Transparent Liquid |
| 1. Cheng Yang, Zheng–Lian Mo, Qiu–Fang Zhang, Jin–Jie Xu, Xiao–Fang Shen, Yue–Hong Pang. (2024) Membrane–protected magnetic covalent organic framework for efficient extraction of estrogens in dairy products. FOOD CHEMISTRY, 438 (14): (137984). [PMID:37979275] [10.1016/j.foodchem.2023.137984] |
| 2. Yue Bao, Yixin Zhai, Siyuan Di, Hailan Qin, Shukui Zhu. (2023) Room-temperature synthesis of magnetic thiophene-based covalent organic frameworks for derivatization-assisted GC–MS analysis of estrogens in environmental water. MICROCHEMICAL JOURNAL, 195 (7): (109524). [PMID:16281057] [10.1016/j.microc.2023.109524] |
| 3. Sailing Chen, Shaowei Wang, Jingyi Zheng, Han Lu, Huiqian Chen, Yunbing Tang, Nan Wang, Yang Zhu, Yiyan Wang, Ping Duan, Ren-shan Ge. (2023) Bisphenol analogues inhibit human and rat 17β-hydroxysteroid dehydrogenase 1: 3D-quantitative structure-activity relationship (3D-QSAR) and in silico docking analysis. FOOD AND CHEMICAL TOXICOLOGY, 181 (114052). [PMID:37758047] [10.1016/j.fct.2023.114052] |
| 4. Tianrun Qian, Jia Bao, Xuepeng Liu, Gerile Oudeng, Weiwei Ye. (2023) A “turn-on” fluorescence resonance energy transfer aptasensor based on carbon dots and gold nanoparticles for 17β-estradiol detection in sea salt. RSC Advances, 13 (40): (27772-27781). [PMID:37731834] [10.1039/D3RA05410A] |
| 5. Yachao Hao, Wei Zhou, Xin Wang, Youping Liu, Xin Di. (2023) Carboxyl-based deep eutectic solvent modified magnetic graphene oxide as a novel adsorbent for fast enrichment and extraction of estrogens in milk prior to HPLC-UV analysis. MICROCHEMICAL JOURNAL, 193 (109050). [10.1016/j.microc.2023.109050] |
| 6. Qingqing Zhou, Yunli Duan, Zhigang Xu, Yu Tian, Zhimin Liu, Chunbo Liu, Pei He, Zhihua Liu, Xiaoxi Si. (2023) A molecularly imprinted fiber array solid-phase microextraction strategy for simultaneous detection of multiple estrogens. Journal of Materials Chemistry B, 11 (22): (4991-4999). [PMID:37218576] [10.1039/D3TB00555K] |
| 7. Jing Yang, Hao Liu, Yan Huang, Li Li, Xiaoli Zhu, Yaping Ding. (2023) One-step hydrothermal synthesis of near-infrared emission carbon quantum dots as fluorescence aptamer sensor for cortisol sensing and imaging. TALANTA, 260 (124637). [PMID:37172433] [10.1016/j.talanta.2023.124637] |
| 8. Qing Liu, Chao Yan, Yan Wang. (2023) Submicron Nonporous Silica Particles for Enhanced Separation Performance in pCEC. MOLECULES, 28 (8): (3542). [PMID:37110774] [10.3390/molecules28083542] |
| 9. Xuan Ma, Yue Wang, Wenting Wang, Jake Heinlein, Lisa D. Pfefferle, Xuemeng Tian. (2023) Strategic preparation of porous magnetic molecularly imprinted polymers via a simple and green method for high-performance adsorption and removal of meropenem. TALANTA, 258 (124419). [PMID:36893497] [10.1016/j.talanta.2023.124419] |
| 10. Haojie Zeng, Feiyun Sun, Jianjun Zhang, Ying Wang, Songwen Yang, Dingyu Xing. (2023) Gradient crosslinking optimization for the selective layer to prepare polyvinyl alcohol (PVA) nanofiltration (NF) membrane: The enhanced filtration performance and potential rejection for EDCs. JOURNAL OF MEMBRANE SCIENCE, 675 (121548). [10.1016/j.memsci.2023.121548] |
| 11. Xuhong Cai, Junbo Liu, Dadong Liang, Shanshan Tang, Bao Xu. (2023) Construction of a QCM sensor for detecting diethylstilbestrol in water based on the computational design of molecularly imprinted polymers. Arabian Journal of Chemistry, 16 (104601). [10.1016/j.arabjc.2023.104601] |
| 12. Sun Min, Wang Xiuqin, Ding Yali, Feng Juanjuan. (2022) Titania hybridized melamine–formaldehyde aerogel for online in-tube solid-phase microextraction of polycyclic aromatic hydrocarbons prior to HPLC–DAD. MICROCHIMICA ACTA, 189 (12): (1-10). [PMID:36416994] [10.1007/s00604-022-05572-3] |
| 13. Lanbo Bi, Jimin Shen, Zhuoran Yao, Jing Kang, Shengxin Zhao, Pengwei Yan, Binyuan Wang, Zhonglin Chen. (2022) Preparation and Adsorption Properties of Magnetic Molecularly Imprinted Polymers for Selective Recognition of 17β-Estradiol. Separations, 9 (11): (381). [10.3390/separations9110381] |
| 14. Pengfei Zhao, Sisi Tang, Xiaodan Wu, Yu Chen, Kangling Tang, Jinli Fu, Huibin Lei, ZhaoXia Yang, Zhaohui Zhang. (2023) Imprinted ratiometric fluorescence capillary sensor based on UiO-66-NH2 for rapid determination of sialic acid. TALANTA, 253 (124081). [10.1016/j.talanta.2022.124081] |
| 15. Liangliang He, Chanjuan Chen, Shuyi Duan, Yang Li, Chuan Li, Xinsheng Yao, Frank J. Gonzalez, Zifei Qin, Zhihong Yao. (2023) Inhibition of estrogen sulfation by Xian-Ling-Gu-Bao capsule. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 225 (106182). [PMID:36152789] [10.1016/j.jsbmb.2022.106182] |
| 16. Yanqun Yang, Yipeng Huang, Zhuqiang Wu, Rui Shi, Zhengyi Chen, Guihua Ruan. (2022) Porous capillary monolithic column coupled with ultrahigh performance liquid chromatography-tandem mass spectrometry for fast and effective separation and determination of estrogens. ANALYTICA CHIMICA ACTA, 1227 (340270). [PMID:36089309] [10.1016/j.aca.2022.340270] |
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| 18. Hui Lyu, Xinze Wu, Yinpeng Yang, Huaixia Chen, Xueping Dang, Xiaolan Liu. (2022) Preparation, characterization and application of double yolk–shell structure magnetic molecularly imprinted polymers for extraction of 17β-estradiol. NEW JOURNAL OF CHEMISTRY, 46 (24): (11927-11933). [10.1039/D2NJ00237J] |
| 19. Yuping Zhang, Ning Wang, Zhenyu Lu, Na Chen, Chengxing Cui, Xinxin Chen. (2022) Smart Titanium Wire Used for the Evaluation of Hydrophobic/Hydrophilic Interaction by In-Tube Solid Phase Microextraction. MOLECULES, 27 (7): (2353). [PMID:35408750] [10.3390/molecules27072353] |
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| 22. Mingxia Sun, Juanjuan Feng, Jiaqing Feng, Haili Sun, Yang Feng, Xiangping Ji, Chunying Li, Sen Han, Min Sun. (2022) Biochar nanosphere- and covalent organic framework nanosphere-functionalized titanium dioxide nanorod arrays on carbon fibers for solid-phase microextraction of organic pollutants. CHEMICAL ENGINEERING JOURNAL, 433 (133645). [10.1016/j.cej.2021.133645] |
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| 25. Xiaoxiao Zhu, Yijun Zhang, Pengfei Liu, Xiuzhi Bai, Na Chen, Yuping Zhang. (2021) Carbonized Aramid Fiber as the Adsorbent for In-Tube Solid-Phase Microextraction to Detect Estrogens in Water Samples. Journal of Chemistry, 2021 (9970518). [10.1155/2021/9970518] |
| 26. Yi Zhang, Lingling Wang, Wen-Long Wang, Cheng Yang, Yongwei Feng, Xueli Shi. (2021) Visual-afterglow dual-mode immunochromatographic strip for 17β-estradiol detection in milk. TALANTA, 232 (122427). [PMID:34074413] [10.1016/j.talanta.2021.122427] |
| 27. Kejian Tian, Fanxing Meng, Qi Meng, Yan Gao, Lili Zhang, Le Wang, Yuqing Wang, Xue Li, Hongliang Huo. (2020) The Analysis of Estrogen-Degrading and Functional Metabolism Genes in Rhodococcus equi DSSKP-R-001. International Journal of Genomics, 2020 (9369182). [PMID:32908857] [10.1155/2020/9369182] |
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| 33. Wenqi Li, Jing Zhang, Wenli Zhu, Peige Qin, Qian Zhou, Minghua Lu, Xuebin Zhang, Wuduo Zhao, Shusheng Zhang, Zongwei Cai. (2020) Facile preparation of reduced graphene oxide/ZnFe2O4 nanocomposite as magnetic sorbents for enrichment of estrogens. TALANTA, 208 (120440). [PMID:31816803] [10.1016/j.talanta.2019.120440] |
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| 37. Liang-Liang Qian, Rui-Xian Li, Hai-Tao Gao, Chun-Min Wang, Lei Li, Qian Xu, Jian Li. (2018) Determination of Five Sex Hormones in Urine Samples for Early Evaluation of Male Reproductive Toxicity Induced by Phthalate Esters in Rats. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 66 (40): (10588–10597). [PMID:30207723] [10.1021/acs.jafc.8b03082] |
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| 1. Cheng Yang, Zheng–Lian Mo, Qiu–Fang Zhang, Jin–Jie Xu, Xiao–Fang Shen, Yue–Hong Pang. (2024) Membrane–protected magnetic covalent organic framework for efficient extraction of estrogens in dairy products. FOOD CHEMISTRY, 438 (14): (137984). [PMID:37979275] [10.1016/j.foodchem.2023.137984] |
| 2. Yue Bao, Yixin Zhai, Siyuan Di, Hailan Qin, Shukui Zhu. (2023) Room-temperature synthesis of magnetic thiophene-based covalent organic frameworks for derivatization-assisted GC–MS analysis of estrogens in environmental water. MICROCHEMICAL JOURNAL, 195 (7): (109524). [PMID:16281057] [10.1016/j.microc.2023.109524] |
| 3. Sailing Chen, Shaowei Wang, Jingyi Zheng, Han Lu, Huiqian Chen, Yunbing Tang, Nan Wang, Yang Zhu, Yiyan Wang, Ping Duan, Ren-shan Ge. (2023) Bisphenol analogues inhibit human and rat 17β-hydroxysteroid dehydrogenase 1: 3D-quantitative structure-activity relationship (3D-QSAR) and in silico docking analysis. FOOD AND CHEMICAL TOXICOLOGY, 181 (114052). [PMID:37758047] [10.1016/j.fct.2023.114052] |
| 4. Tianrun Qian, Jia Bao, Xuepeng Liu, Gerile Oudeng, Weiwei Ye. (2023) A “turn-on” fluorescence resonance energy transfer aptasensor based on carbon dots and gold nanoparticles for 17β-estradiol detection in sea salt. RSC Advances, 13 (40): (27772-27781). [PMID:37731834] [10.1039/D3RA05410A] |
| 5. Yachao Hao, Wei Zhou, Xin Wang, Youping Liu, Xin Di. (2023) Carboxyl-based deep eutectic solvent modified magnetic graphene oxide as a novel adsorbent for fast enrichment and extraction of estrogens in milk prior to HPLC-UV analysis. MICROCHEMICAL JOURNAL, 193 (109050). [10.1016/j.microc.2023.109050] |
| 6. Qingqing Zhou, Yunli Duan, Zhigang Xu, Yu Tian, Zhimin Liu, Chunbo Liu, Pei He, Zhihua Liu, Xiaoxi Si. (2023) A molecularly imprinted fiber array solid-phase microextraction strategy for simultaneous detection of multiple estrogens. Journal of Materials Chemistry B, 11 (22): (4991-4999). [PMID:37218576] [10.1039/D3TB00555K] |
| 7. Jing Yang, Hao Liu, Yan Huang, Li Li, Xiaoli Zhu, Yaping Ding. (2023) One-step hydrothermal synthesis of near-infrared emission carbon quantum dots as fluorescence aptamer sensor for cortisol sensing and imaging. TALANTA, 260 (124637). [PMID:37172433] [10.1016/j.talanta.2023.124637] |
| 8. Qing Liu, Chao Yan, Yan Wang. (2023) Submicron Nonporous Silica Particles for Enhanced Separation Performance in pCEC. MOLECULES, 28 (8): (3542). [PMID:37110774] [10.3390/molecules28083542] |
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