Uric acid is the major end product of purine catabolism in humans and exists primarily as free uric acid or urate in blood, urine, and tissues. Uric acid quantification is a commonly used technique in clinical biochemical analysis and metabolic research and is widely applied in hyperuricemia ...
Purine metabolism disorders and hyperuricemia research are mainly used to analyze increased uric acid production, reduced uric acid excretion, changes in xanthine oxidoreductase activity, and inflammatory responses induced by urate crystals. Experimental design should distinguish purine ...