Roles of GLP-1R, GIPR, and GCGR in Metabolic Regulation of Obesity and Type 2 Diabetes and in Multi-Receptor Agonist Therapy
GLP-1R, GIPR, and GCGR jointly regulate pancreatic hormone secretion, hepatic glucose output, feeding behavior, and energy metabolism. Multi-receptor agonists improve the overall metabolic treatment of obesity and type 2 diabetes by balancing glucose-lowering effects, appetite suppression, and ...
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