用于检测、定量和定位抗原与抗体的技术——ELISA、免疫印迹、免疫组化与流式细胞术。以下是我们知识库中标注该主题的实验方案、常见问题与技术文章。
ADAR1 is an important RNA-editing enzyme that catalyzes adenosine-to-inosine (A-to-I) editing in double-stranded RNA (dsRNA), reducing the recognition of endogenous dsRNA by nucleic acid-sensing systems such as MDA5, PKR, and ZBP1. Tumor cells can exploit ADAR1 to maintain RNA immune tolerance, ...
ADAR1是催化双链RNA（double-stranded ...
Necroptosis is a form of regulated cell death centered on the RIPK3–MLKL execution axis. Plasma membrane rupture can be accompanied by the release of DAMPs, tumor antigens, and inflammatory signals, thereby directly linking cell death to changes in the tumor immune microenvironment. ...
坏死性凋亡（necroptosis）是一类以RIPK3–MLKL轴为核心执行机制的调节性细胞死亡，其质膜破裂可伴随DAMPs、肿瘤抗原及炎症信号释放，从而将细胞死亡与肿瘤免疫微环境变化直接连接。RIPK1依赖性信号、ZBP1介导的非经典RIPK3激活以及死亡前炎症转录共同决定其免疫输出，而不同细胞类型和微环境背景又可使坏死性凋亡呈现抗肿瘤或促肿瘤的双向效应。 ...
常与免疫学实验一起研究的技术。
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