INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2020
·
IF 5.162
Ning Zhao,Henan Zou,Shuang Sun,Cuiping Yu
The interaction between sodium alginate (SA) and turbot myofibrillar proteins (TMP) and the effects of SA concentration (0.1%–0.5%) on the rheological and emulsifying properties of the mixture at neutral pH were investigated. TMP and SA formed complexes through electrostatic repulsion and hydrophobic interaction. The FT-IR analysis indicated that hydrogen bonding was also related to the interaction. With the addition of SA, the electrostatic repulsion between molecules enhanced, which prevented protein aggregation and improved the stability of dispersions. The TMP/SA mixture showed non-Newtonian shear-thinning behavior. The viscosity gradually increased with the increasing SA concentration. TMP and SA formed an interconnected gel-like network structure with a predominant elastic behavior. The strength of network increased due to the strong repulsion between the two biopolymers . Both EAI and ESI of TMP significantly increased after SA addition. The addition of SA reduced droplet size of emulsions. The emulsions also showed pseudoplastic behavior. Addition of SA increased stability of emulsions by increasing viscosity of continuous phase. Complexation with SA effectively improved the rheological and emulsifying properties of fish myofibrillar proteins. These results contributed to the efficient utilization of marine fish proteins as functional ingredients in food products.
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高影响因子
Marine Drugs
·
2021
·Vol. 20
·期 1
·16
·
IF 5.118
Wei Chen,Kaixiong Ye,Xiaoji Zhu,Huihui Zhang,Ranran Si,Jianing Chen,Zijun Chen,Kaili Song,Zhicheng Yu,Bingnan Han
Actinomycins as clinical medicine have been extensively studied, while few investigations were conducted to discover the feasibility of actinomycins as antimicrobial natural dye contributing to the medical value of the functional fabrics. This study was focused on the application of actinomycin X2 (Ac.X2), a peptide pigment cultured from marine-derivedStreptomyces cyaneofuscatus, in the dyeing and finishing of silk fabric. The dyeing potential of Ac.X2 with silk vs. cotton fabrics was assessed. As a result, the silk fabric exhibited greater uptake and color fastness with Ac.X2. Through Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), and X-ray diffraction (XRD) analyses, some changes of chemical property for the dyed fabric and Ac.X2 were studied. The silk fabric dyed with Ac.X2 exhibited good UV protection ability. The antibacterial properties of dyed and finished silk were also evaluated, which exhibited over 90% antibacterial activity even after 20 washing cycles. In addition, the brine shrimp assay was conducted to evaluate the general toxicity of the tested fabric, and the results indicated that the dyed silk fabrics had a good biological safety property.
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Science China-Materials
·
2024
·
IF 6.8
Liu Yuanqi,Wang Zhenguo,Pan Yaqin,Liu Tianyu,Zhang Yabin,Zhang Qing,Mo Lixin,Luo Qun,Ma Changqi
Roll-to-roll (R2R) gravure printing has significant potential for the mass production of large-area flexible organic solar cells (FOSCs) owing to its exceptional edge resolution, patternability, high speed, and high throughput. For gravure-printed FOSCs, device performance is critically dependent on the quality of the printed films. During the gravure printing process, printing transfer is a key step that impacts the film thickness and quality. This study delves deeply into the influence of ink viscosity on the ink transfer process, specifically focusing on the transfer rate and defects in printed films. In this work, we developed an ultraviolet-visible (UV-Vis) spectroscopy method to quantify the ink transfer rate during printing. We conducted an in-depth investigation into the relationships among ink viscosity, transfer rate, film thickness, and film homogeneity through ink flow behavior analysis, computational fluid dynamic simulation, and experimental validation. The results demonstrate that the shear adhesion force and duration of contact between the ink and the gravure roll are crucial factors affecting the transfer rate. Furthermore, we identified an organic precursor ink with a viscosity of approximately 25 mPa·s as an optimized ink formulation for R2R gravure printing. With this optimized ink formulation, fully R2R-printed FOSCs with an area of 1 cm 2 achieve a power conversion efficiency (PCE) exceeding 12%.
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BIOSENSORS & BIOELECTRONICS
·
2021
·
IF 10.618
Shixuan Su,Ting Yu,Jing Hu,Yunlei Xianyu
Angiotensin-converting enzyme (ACE) can indicate blood pressure that relates to human health such as the cardiovascular disease. However, current methods are not competent to detect the ACE activity in a rapid and straightforward way. Plasmonic biosensors built on the modulation of metallic nanomaterials have emerged as novel tools for the detection of biomarkers. In this work, we report a bio-inspired strategy for the plasmonic detection of ACE in a rapid, sensitive, and selective way through peptide-mediated assembly of gold nanoparticles (AuNPs). In this biosensor, cysteine-angiotensin I-cysteine can assemble and aggregate AuNPs due to the Au–S bond. The presence of ACE can specifically catalyze the hydrolysis of angiotensin I , thus dissociating the cysteine-cysteine structure of the peptide that results in the disassembly and dispersion of AuNPs. This bio-inspired plasmonic nanosensor enables naked-eyed readout of ACE detection with great selectivity and high sensitivity with a LOD of 0.40 mU/mL. It also allows for the screening of ACE inhibitors and inhibitory peptides for the development of antihypertensive drugs or food. The biosensing technique developed in this work provides a new plasmonic approach that holds great promise as a point-of-care platform for biomedical diagnostics and the food industry.
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高影响因子
Biomaterials Science
·
2020
·Vol. 8
·期 5
·1270-1278
·
IF 6.183
Yanxing Wang,Wei-Dong Lü,Bi Lin,Fan Yang,Miao Feng,Ruichan Lv
In this research, an optimized phosphor combined with naturally green chlorophyll (Phosphor-Chlorophyll, denoted as Ph-chl) was designed for dual-modal luminescence-guided anti-tumor surgery and photodynamic therapy (PDT). A genetic algorithm (GA) is used to solve the “low up-conversion luminescence (UCL) and short-wavelength infrared (SWIR) intensity” problem by coding the proportions of elements in the phosphor in order to find the optimal phosphor with enhanced red UCL emission and SWIR luminescence using Yb/Er in the core and Yb/Nd in the shell. Moreover, when phosphors with different emission light colors (blue and green) are combined with chlorophyll as the control, the results indicate that phosphors with red emission as the energy donor have high PDT efficiency to activate the chlorophyll for reactive oxygen species (ROS) production. Additionally, due to the enhanced penetration and retention (EPR) effect, the as-synthesized Ph-chl could be used for surgery navigation with a higher SWIR imaging effect focusing on cancer rather than normal tissues and paracancerous tissue. Thus, the high dual-modal luminescence guided surgery properties of the final optimized phosphor will promote its further use in minimally-invasive endoscopic clinical surgery navigation.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2020
·
IF 5.774
Shi Gong,Yabing Sun,Ke Zheng,Guilin Jiang,Lian Li,Jingwei Feng
Degradation of quinolone antibiotic levofloxacin (LFX) in water falling film dielectric barrier discharge (DBD) plasma combined with Ag 3 PO 4 loaded activated carbon fibers (Ag 3 PO 4 /ACFs) system was studied. The prepared Ag 3 PO 4 /ACFs were characterized by scanning electron microscope (SEM), X-ray diffraction (XRD) and Brunauer-Emmett-Teller (BET). The results showed that the cubic Ag 3 PO 4 was well loaded on surface of the ACFs with a large specific surface area. Effects of initial concentration of LFX, discharge voltage, initial pH, liquid circulation flow rate, and catalyst dosage on the removal rate of LFX were discussed. The results showed that the degradation efficiency of LFX at 18 min could reach 93% with the addition of Ag 3 PO 4 /ACFs compared with 63% by single DBD plasma (discharge voltage 10 kV, initial concentration of LFX 20 mg/L). The addition of Ag 3 PO 4 /ACFs increased the mineralization rate of LFX from 11% to 46%. The possible degradation pathways of LFX were derived by Gaussian calculation and high-performance liquid chromatography-mass spectrometry (HPLC-MS) analysis, decarboxylation, demethylation, dehydroxylation, side chain decomposition, and ring cleavage involved in the degradation process of LFX.
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Geoenergy Science and Engineering
·
2023
·
IF 0
Junjie Hu,Guicai Zhang,Ping Jiang,Xiang Wang,Lei Wang,Haihua Pei
It is more difficult to control water production in horizontal wells than in vertical wells. It is challenging to predict the water-producing section of a horizontal well and realize staged oil recovery. With water breaking through the oil layer, the water cut of production wells sharply rises. This can even lead to early closure of production wells, which can seriously affect the economic benefits. When researchers explore water control of horizontal wells, they usually use the method of plugging the water-producing section. The success rate is often low due to water flow around the plugged section and pollution of plugging agents in the high-oil saturation area. On the basis of nitrogen for water cresting control, this paper studied the ability of a viscosity reducer (VR) and nitrogen (N 2 ) compound system to inhibit the rise in the water crest. First, a series of two-dimensional quantitative experiments and visualization experiments were conducted to study the influence and mechanism of the VR and N 2 system in controlling water cresting. The results show that compared to N 2 control of water cresting (recovery improved by 2.70%), the compound system greatly improved the water control and oil increase effects of the horizontal well (recovery improved by 26.38%). The VR enters the area with high oil saturation through osmosis to reduce the viscosity of heavy oil and the water-oil mobility ratio . N 2 enhanced the osmosis of the VR in the reservoir. In addition, rheological tests were performed of heavy oil mixtures, and the viscosity reduction mechanism of the VR was analyzed via diffusion-ordered spectroscopy (DOSY) and scanning electron microscopy (SEM). The experiment shows that after addition of the VR, the size of heavy oil deposit was reduced and the asphaltene surface was broken. The VR reduced the viscosity of heavy oil by depolymerizing macromolecular aggregates in heavy oil and preventing them from coming together again. Finally, a field test was conducted in a horizontal well, with a cumulative oil increase of 9286.86 bbl. The research results provide an important guiding significance for water control and oil recovery of horizontal wells.
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FUEL PROCESSING TECHNOLOGY
·
2019
·
IF 4.507
Ibrahim Lawan,Weiming Zhou,Aisha Lawan Idris,Yifan Jiang,Mingxin Zhang,Liwei Wang,Zhanhui Yuan
This study focused on providing a holistic solution to biodiesel instability challenges using a fuel additive . Three different samples of the multi-functional fuel additive (MFA 1, MFA 2 and MFA 3) were synthesized from abundant lignocellulose-based feedstock. Findings from their property evaluation reveal that 29.67 ± 8.08, 44.67 ± 2.31 and 53.33 ± 8.08% 2,2-Diphenyl-1-picrylhydrazyl (DPPH) radical inhibition with the MFA 1, MFA 2 and MFA 3 respectively, which shows an obvious antioxidation property. Also, findings obtained from the analysis of the additives using differential scanning calorimeter (DSC) reveal a reduction in crystallization temperature of biodiesel by 3.96, 8.79 and 14.25 °C with the MFA 1, MFA 2 and MFA 3 respectively, which signifies a robust anti-freezing property. Furthermore, the additives exhibited antibacterial and antifungal properties against some bacterial and fungal strains that were reported to have negative effects on biodiesel ( Bacillus pumilus and Paecilomyces variotii respectively). For instance, the least zones of inhibition of 22.33 ± 0.58and 35.00 ± 5.03 mm were recorded with MFA 1 against the Bacillus pumilus and Paecilomyces variotii respectively using agar well method. Strikingly, biodiesel doped with MFA 2 exhibited improved oxidation stability, lower freezing temperature and strong inhibition against the microbial strains without taking other important properties of biodiesel out of standard specifications.
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Frontiers in Nutrition
·
2022
·
IF 6.59
Cai Qizhen,Zhang Yun,Fang Xiaofeng,Lin Suyun,He Zhirong,Peng Shengfeng,Liu Wei
In this study, a novel emulsion, thymol (Thy) and lauric acid (LA) emulsion (Thy/LA-Emulsion) was prepared by homogenizing eutectic solvent (Thy/LA mixture) and caseinate solution. The effects of different thymol and lauric acid mass ratio on the formation, stability, and antibacterial activity of emulsions were studied. Compared with thymol alone, adding lauric acid (25, 50, and 75%) could enhance the antibacterial efficacy of the emulsions. Among them, Thy/LA25%-Emulsion could be stored at room temperature for a month without the increase of particle size, indicating that the addition of LA had not impacted the stability of emulsions. Meanwhile, Thy/LA25%-Emulsion exhibited a greater inhibition zone (3.06 ± 0.12 cm) and required a lower concentration (0.125 mg/mL) to completely inhibit the growth of Listeria monocytogenes. Consequently, Thy/LA25%-Emulsion demonstrated the best antibacterial activity and physicochemical stability due to its long-term storage stability. Our results suggest that Thy/LA25%-Emulsion may become a more functional natural antibacterial agent with greater commercial potential owing to its cheaper raw materials, simpler production processes, and better antibacterial effect in the food industry.
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PubMed
高影响因子
CHINESE SCIENCE BULLETIN
·
2012
·Vol. 57
·期 31
·4012-4018
·
IF 1.321
Wang Dan,Su HongYing,Liu YanHong,Wu ChangQiang,Xia ChunChao,Sun JiaYu,Gao FaBao,Gong QiYong,Song Bin,Ai Hua
Construction of multifunctional/multimodality nanoparticles for cancer diagnosis and therapy has become an attractive area of investigation. In this report, we designed a multimodality nanoprobe for cell labeling, and can be detectable by both magnetic resonance and near infrared (NIR) fluorescence imaging. Multiple hydrophobic superparamagnetic iron oxide (SPIO) nanocrystals are self-assembled into nanocomposites in water phase with the help of partially alkylated hyperbranched polycation, polyethylenimine (PEI), which already conjugated with the indocyanine dye Cy5.5 and can be used for cell imaging under NIR fluorescence imaging. The amphiphilic PEI/SPIO nanocomposites have a strong T
2 relaxivity. The iron uptake process in MCF-7/Adr displays a time dependent behavior. Confocal laser scanning microscopy reveals that the nanoprobes are internalized into the cytoplasm of MCF-7/Adr after 24 h labeling. Both MR and NIR fluorescence imaging showed strong image contrast against unlabeled cells. Under a clinical MRI scanner, labeled cells in gelatin phantom present much darker images than controlled ones. The T
2 relaxation rate of the labeled cells is 98.2 s −1 , significantly higher than that of the control ones of 2.3 s −1 . This study provides an important alternative to label MCF-7/Adr at optimized low dosages with high efficiency, and may be useful to label other biologically important cells and track their behaviors in vivo .
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Scientific Reports
·
2017
·Vol. 7
·期 1
·1-11
·
IF 4.259
Zhao Yating,Wang Yu,Ran Fu,Cui Yu,Liu Chang,Zhao Qinfu,Gao Yikun,Wang Da,Wang Siling
In recent years, spherical nanoparticles has been studied extensively on biomedical applications including bioimaging and biosensing, diagnostics and theranostics, but the effect of the shape of nanoparticles has received little attention. In the present study, we designed three different shaped fluorescent mesoporous silica nanoparticles (MSNs), long rod nanoparticles (NLR), short rod nanoparticles (NSR), and spherical nanoparticles (NS) to systematically examine their behavior in vivo after oral administration. The results of the ex vivo optical imaging study in mice indicated that rod nanoparticles had a longer residence time in the gastrointestinal compared with spherical nanoparticles. The in vivo biodistribution showed that all the orally administered MSNs were mainly taken up by the liver, and kidney. NLR had a great capacity to overcoming rapid clearance by the RES and exhibited a longer circulation in the blood than NSR and NS. During renal excretion, the spherical nanoparticles were cleared faster than rod nanoparticles. In addition, it was also found that MSNs can be degraded in vivo and NSR were degraded faster than NLR and NS probably owing to their higher specific surface area. The pharmacokinetic results demonstrated that nifedipine(NI)-loaded NLR had a higher bioavailability than NI-loaded NSR and NS.
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PubMed
高影响因子
JOURNAL OF POROUS MATERIALS
·
2020
·Vol. 27
·期 5
·1455-1466
·
IF 2.183
Yuan Zhishuai,Cheng Yuchun,Ma Shoutao,Jiang Zhen,Zhou Yisi,Wang Yingjun,Zhang Wei,Suo Yanhua
A new method called Instant Exactness Synthesis (IES), which was applied to prepare SAPO-11 molecular sieve, was introduced innovatively. The metal–acid bifunctional Ni/SAPO-11-IES catalyst with a Ni content of 4% was prepared by the impregnation method. Ni/SAPO-11-H catalyst was prepared as a comparative sample through the traditional hydrothermal method. In addition, the growth mechanism was used to explain the excellent performance of catalyst prepared by IES method in detail. The structure of Ni/SAPO-11-IES was confirmed via XRD and TEM characterization. The pore structure of the molecular sieve was determined by nitrogen adsorption and desorption. 29 Si MAS NMR measurement was used to illustrate multiple silicon environment which supported the excellent acidity in NH 3 -TPD measurement. Furthermore, the favourable dispersibility of Ni species was proved by the mapping of the elements and EDS. Benefiting from the superior performance of materials, Ni/SAPO-11-IES catalyst exhibited a higher catalytic performance for n-heptane hydroisomerization with n-heptane conversion of 82% and isoheptane selectivity of 86%, respectively, compared with other catalysts in the same system. The study also provides new ideas for the preparation of molecular sieve materials.
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高影响因子
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