MATERIALS RESEARCH BULLETIN
·
2026
·
IF 5.7
Weilong Bao,Hang Lu,Fei Li,Siyuan Lu
Morphological and size control of Pt nanoparticles (PtNPs) has long been pursued to improve the catalytic performance of Pt-based electrochemical sensors during recent decades. In this study, a high‑performance hydrogen peroxide sensor was developed by electrochemically depositing PtNPs onto a polyaniline‑modified glassy carbon electrode (PANI/GCE). Subsequently, the PtNPs/PANI/GCE electrode was separately subjected to two distinct methods, namely square wave (SW) treatment and square wave voltammetry (SWV). It was found that SWV was able to alter the exposed surface of platinum nanoparticles from (111) to (200), which leads to the formation of the angular nano-edges on the original Pt nanospheres. This structural transformation effectively increased the number of active sites and enlarged the effective surface area for the catalytic redox reaction of hydrogen peroxide. Owing to such advantages, the prepared PtNPs/PANI/GCE-SWV electrode exhibits a wide linear range from 50 μM to 30 mM and an excellent sensitivity of 294.90 μA·mM −1 ·cm −2 for H 2 O 2 detection. In addition, SWV endowed the fabricated sensor with superior stability and reproducibility, thereby demonstrating promising prospects in the commercialization of stretchable and wearable biosensors.
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JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2026
·
IF 4.1
Qing Yang,Jingsen Zhang,Mingyi Lv,Chuanjie Chen,Yue Hua,Hong Li,Lanbo Di
Regulating the cobalt valence state is a crucial strategy for enhancing nonenzymatic glucose detection. In this study, two self-supported Co 3 O 4 nanocomposites were fabricated on plasma-pretreated carbon cloth (CC P ) by electrodepositing an α-Co(OH) 2 precursor followed by either plasma treatment yielding Co 3 O 4 /CC P -P or calcination yielding Co 3 O 4 /CC P -C. Structural characterization reveals that plasma pretreatment enriches the CC P surface with abundant oxygen-containing functional groups (OCGs), significantly improving its hydrophilicity. In addition, the Co 3 O 4 /CC P -C exhibits a phase-pure structure enriched with multiple Co 3+ and surface-adsorbed oxygen (O Ads ). These properties coupled with its rapid electron-transfer capability significantly promote the glucose oxidation reaction. Compared with Co 3 O 4 /CC P -P, the Co 3 O 4 /CC P -C electrode presents markedly higher electrocatalytic activity toward glucose oxidation, featuring superior sensitivities of 6380 μA·mM −1 ·cm −2 (0.05–0.4 mM) and 2070 μA·mM −1 ·cm −2 (0.4–1.4 mM), along with a lower limit of detection (2.9 μM). The Co 3 O 4 /CC P -C electrode also exhibits excellent selectivity, good preparation repeatability (relative standard deviation (RSD) = 2.14%), operational repeatability (RSD = 1.36%) and favorable stability (RSD = 2.40%). This study provides a promising approach for developing efficient non-enzymatic glucose oxidation Co-based electrocatalysts, and gets insights into the influence mechanism by engineering the Co valence state.
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CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
He Zhao,Chu Xu,Caobin Zhou,Ling Zhang,Chunzhong Li
Existing triboelectric nanogenerators (TENGs) for wearable sweat sensors are plagued by low power density, which restricts their practical application. This study focuses on boosting TENGs output power via a fluorinated bi-layer electronic textile (e-textile) fabricated by electrospinning rotary collection, enabling self-powered dual functionality: real-time electrochemical sweat sensing and human motion detection. The key design includes a PCLU-HFDD negative triboelectric layer (molecularly incorporated with hexadecafluorodecanediol to enhance electron affinity) and a poly(lactic- co -glycolic acid) (PLGA) positive layer. Rotary collection creates vein-like nanostructures on PCLU-HFDD yarns (6.2 μm roughness, 114.8° water contact angle), increasing contact area. The PCLU-HFDD TENG achieves a high power density of 0.66 W m −2 , an open-circuit voltage (Voc) of 117.08 V, and excellent stability over 35,000 contact-separation cycles. Critically, integrated with both sweat-sensing and motion-detection capabilities, the e-textile enables 180-min continuous glucose monitoring (under sedentary conditions) and recognition of human motions. This work confirms that the power enhancement not only overcomes the bottleneck of TENGs for wearable sensors but also facilitates dual-modal health monitoring, advancing the development of practical wearable bioelectronics.
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MICROCHEMICAL JOURNAL
·
2026
·
IF 5.1
Jiaqi Geng,Yanxin Lv,Zhitan Huang,Faman Lin,Neha,Brij Mohan,Wei Sun
Chlorogenic acid (CGA), a dietary polyphenol with antioxidant and therapeutic benefits, can be harmful at high concentrations, necessitating sensitive detection in food. This study presents a ZrO 2 -ZrC-doped laser-induced graphene (ZrO 2 -ZrC-LIG) electrode prepared via a one-step laser carbonization of UiO-66/polyimide film. Structural analysis reveals a three-dimensional porous network with uniformly dispersed ZrO 2 and ZrC nanoparticles in graphene, which increases defect density, conductivity and surface area. The optimal conditions of laser-induced parameters such as power and carving depth for the electrode fabrication were selected. Under the optimal conditions, the electro-oxidation of CGA on the ZrO 2 -ZrC-LIG electrode was carefully investigated with electrochemical parameters calculated. The presence of ZrO 2 , ZrC and LIG exhibited an enhancement to the CGA oxidation with a pair of well-define redox peaks appeared, which was attributed to the faster electron transfer, higher electrocatalytic activity and synergistic effects. When integrated with a wireless portable electrochemical workstation, the fabricated sensor shows excellent analytical performance for CGA detection, including a wide linear range (0.1 μM to 1.0 mM), a low detection limit of 33 nM (3σ), along with high selectivity, stability, and reproducibility. When applied to apple and Eucommia ulmoides samples, it achieves the recoveries of 99.26–103.14%, confirming good analytical reliability. This simple and scalable method offers a promising strategy for developing flexible, portable electrochemical sensors for food safety and nutrition monitoring.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2026
·
IF 4.6
Ya Zou,Mei Chen,Qingzhi Liu,Kezhen Qi,Jieli He
This study reports the successful synthesis of graphitic carbon nitride quantum dots (g-C 3 N 4 QDs) that demonstrate remarkable fluorescence properties and excellent dispersion through a hydrothermal method. Leveraging the specific fluorescence quenching effect of ag + on g-C 3 N 4 QDs together with the strong chelating affinity of glutathione (GSH) for ag + , a novel “on–off–on” fluorescence sensing platform was developed to enable sequential and highly sensitive detection of both ag + and GSH. This probe exhibited outstanding sensitivity, anti-interference ability, and selectivity with detection limits of 0.0114 μM for ag + and 0.3916 μM for GSH. Mechanistic studies revealed that the fluorescence “off” state was mainly governed by a photoinduced electron-transfer (PET) effect, with additional contributions from the internal filtering effect (IFE). Conversely, the fluorescence “on” state was restored when GSH coordinated with ag + , thereby blocking the PET pathway and recovering the intrinsic fluorescence of g-C₃N₄ QDs. Furthermore, spiked-recovery experiments in real water and serum samples yielded satisfactory results, demonstrating the sensor's strong practical applicability and providing a reliable analytical approach for environmental monitoring and biomedical analysis
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SENSORS AND ACTUATORS B-CHEMICAL
·
2026
·
IF 7.7
Yixue Chen,Huaiyu Song,Yan Qin,Yu Liu,Ying Xie,Zhenyu Chu,Wanqin Jin
Pyruvate is one of the most important intermediate metabolites in the fermentation process, thereby making it a potential indicator for monitoring and regulating the fermentation process. Since the fermentation broth is usually complex, including microorganisms, various ions, organic compounds, etc., it is necessary to develop a highly selective method for detecting pyruvate. Therefore, in this work, we proposed an ultrasensitive electrochemical enzymatic biosensor for pyruvate determination at a low working potential through constructing Prussian blue@Au nanoframes (PB@Au NFs) with improved conductivity and high electrocatalytic ability. Due to the strong catalytic ability of PB nanoframes for the reduction of H 2 O 2 , the as-prepared sensor initially demonstrated extremely 2.7-fold sensitivity toward H 2 O 2 than the non-frame structured PB nanocubes. Furthermore, after the conditions for pyruvate detection were systematically optimized, the fabricated sensor was able to effectively identify pyruvate ranging from 5 μM to 0.895 mM at -0.2 V which represented an orders-of-magnitude improvement in sensitivity over existing sensors. Meanwhile, the low working potential and the highly precise recognition ability of pyruvate oxidase ensured the high selectivity of the prepared sensor, and the sensor also showed excellent reproducibility and long-term stability. Finally, our biosensor was employed to detect pyruvate in the real microbial fermentation liquid, giving an excellent accuracy with RSD values of 1.44% - 4.64%. This work provides a new strategy approach for the design and establishment of stable pyruvate sensors and offered a usefulness approach for the pyruvate detection with high performance.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2026
·
IF 5.4
Hecheng Yao,Shuyi Li,Chaohuan Yang,Chenchen Liao,Yuchan Li,Zhimin Guo,Guoyong Wang,Yan Liu
With the growing emphasis on personalized health management, point-of-care testing has garnered significant interest, creating a pressing demand for biosensors that are both highly sensitive and user-friendly. Herein, we develop a dual-function sensor on a Janus fabric for monitoring sweat glucose and lactate. The Janus material provides the critical function of unidirectional sweat transport for efficient collection while also being endowed with antibacterial properties and breathability to ensure user comfort during extended wear. The electrochemical electrode was fabricated via a sequential process of screen-printing, electropolymerization of Prussian blue, and modification with MXene and specific enzymes. The incorporation of MXene significantly reduces the electrical impedance of the electrode, thereby enhancing its electrochemical performance. The sensor offers broad detection ranges (0–500 μM for glucose and 0–25 mM for lactate) with low detection limits (0.6 μM and 0.145 mM, respectively). Furthermore, the detection sensors exhibit outstanding long-term stability, excellent reproducibility, and strong anti-interference capability. Moreover, the integrated sensor successfully monitored changes in glucose and lactate concentrations in human sweat, demonstrating significant potential for applications in health management and exercise monitoring.
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ANALYST
·
2026
·
IF 3.3
Xueying Zhu,Shuo Tian,Shuyun Chen,Yunsen Wang,Dianping Tang
As a key alkaloid, the concentration of xanthine in the body often reflects various physiological or pathological states of the human body. However, conventional methods for xanthine detection often suffer from time-consuming procedures and a narrow linear range. The present study screened 30 nanozymes with varying Fe/S molar ratios using a hydrogen peroxide-3,3',5,5'-tetramethylbenzidine (H2O2-TMB) colorimetric system and identified FeS-loaded nitrogen-doped carbon nanozyme (Fe300S5-NC) as a highly efficient catalyst. Inspired by the biological metabolic pathway of xanthine, an XOD/Fe300S5-NC/TMB colorimetric system was constructed for the detection of xanthine. The constructed colorimetric sensing platform demonstrated facile operation and rapid response, with a linear xanthine detection range of 10–1000 μM and a detection limit of 0.97 μM. This work provides a viable strategy for designing artificial enzymes with high peroxidase-like activity, indicating potential for biosensing applications.
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MICROCHEMICAL JOURNAL
·
2026
·
IF 5.1
Chenyan Lu,Dajie Zou,Ning Zhang,Huye Li,Yanyan Jia,Huan Wang
In this study, the hexane extract of Asters tataricus was used as the carbon source, and ethylenediamine and 4-bromophenylene diamine were selected as dopants to prepare nitrogen and bromine co-doped carbon dots (N,Br-CDs) by the hydrothermal synthesis method. The obtained fluorescent probe has a uniform particle size distribution, good water solubility and high stability, with a fluorescence quantum yield of 48.43%. Under 420 nm excitation conditions, N,Br-CDs exhibited the strongest fluorescence emission at 513 nm, indicating that the sensing system was in the “ON” state. Subsequently, TA was introduced as a quencher to induce static quenching of the N,Br-CDs system, significantly weakening the fluorescence intensity and switching the sensing system from “ON” to “OFF”. Finally, after EM was introduced into the N,Br-CDs/TA system, EM preferentially formed a complex with TA and weakened its quenching effect on the quantum dots, thereby achieving fluorescence recovery and returning the sensing system from the “OFF” state to the “ON” state. Based on the above mechanism, an “ON-OFF-ON” fluorescence sensing system with N,Br-CDs as the luminescent substrate was constructed for the sensitive detection of TA and EM. The results showed that the system exhibited good linear response to TA, with the linear ranges being 1.50–22.94 μM and 34.88–348.42 μM, respectively, and the limits of detection being 0.2168 μM and 2.1797 μM, respectively (LOD, S/N = 3). The linear range for EM was 1.93–377.08 μM, with a detection limit of 0.6693 μM. Furthermore, the sensor system was capable of quantitatively determining TA and EM in human serum, Huangshui River water, and milk matrices, demonstrating its potential for broad application in environmental monitoring and bioanalysis.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2026
·Vol. 37
·期 3
·212
·
IF 2.8
Zhan Mingfang,Li Jiayan,Alam Mohammad Jahidul,Akter Sima,Wan Hong,Mahmud Sakil
Acetaminophen (paracetamol, PA) is among the most widely used analgesic and antipyretic drugs, necessitating sensitive and reliable monitoring in pharmaceutical and clinical matrices. Although numerous PA sensors have been reported, many rely on complex nanocomposites or multistep fabrication, limiting reproducibility and scalability. Here, a minimalist yet highly efficient sensing strategy is demonstrated by electrodepositing a uniformly nanostructured nickel oxide (NiO) film directly onto a disposable screen-printed carbon electrode (SPCE). This rational single-step deposition yields a catalytically active surface with markedly enhanced electron-transfer characteristics. The resulting NiO/SPCE exhibits a linear response from 1.0 to 9.17 μM and a detection limit of 0.11 μM, outperforming many previously reported metal-oxide-based PA sensors. Morphological characterization confirms the formation of a smooth, compact, and homogeneously distributed NiO layer, while differential pulse voltammetry highlights excellent selectivity, minimal interference from common ions and metabolites, and strong operational stability. Together, these features establish the NiO/SPCE as a reproducible, low-cost, and high-performance platform for the precise determination of PA in pharmaceutical formulations and human fluids, with clear potential for integration into portable point-of-care systems.
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LUMINESCENCE
·
2026
·Vol. 41
·期 1
·e70417
·
IF 3
Shengnan Yin,Changlun Tong
The monitoring of alkaline phosphatase (ALP) activity and pyrophosphate (PPi) concentration is critical for assessing phosphorus dynamics and eutrophication in aquatic ecosystems. However, on-site, rapid detection of these dual targets in complex water matrices remains a challenge. In this work, a nitrogen-doped carbon dots (N-CDs)-Eu 3+ -tetracycline (TC)-based ratiometric fluorescence probe was constructed for turn “off–on” determination of PPi and ALP based on the strong binding interaction between PPi and Eu 3+ and PPi hydrolyzed by ALP. In the N-CDs-Eu 3 + -TC system, with the addition of PPi, PPi could replace the N-CDs to form the PPi-Eu 3+ -TC multicomplex, and N-CDs were released, resulting in the fluorescence quenching of Eu 3+ and fluorescence recovery of N-CDs. ALP could hydrolyze PPi to PO 4 3− , which could destroy the PPi-Eu 3+ -TC multicomplex and form the N-CDs-Eu 3+ -TC multicomplex again, and the fluorescence of Eu 3+ at 617 nm was recovered. The N-CDs-Eu 3+ -TC-based ratiometric fluorescent probe possesses a quick fluorescence response, obvious fluorescence color variance, and excellent selectivity and sensitivity with LOD of 40 nM for PPi and 0.03 U/L for ALP. The proposed probe was successfully applied for the detection of PPi and ALP in the actual environmental water samples or serum samples.
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Advanced Science
·
2026
·
IF 14.1
Ri Wang,Xiaofei Deng,Bo Chen,Jienan Shen,Wei Xu,Yingjie Zhu,Yi Zhang,Hui Yang
Illicit drug abuse presents a global challenge to public health and security, creating an urgent need for reliable detection methods to curb trafficking and mitigate societal harm. Methamphetamine (METH), a highly addictive and widely circulated stimulant, requires urgent monitoring solutions. We introduce an approach for the rapid and direct detection of METH using an electrochemical sensor enhanced with MXene nano-interfaces that operates on the principle of electrochemical oxidation. Theoretical simulations are conducted to elucidate the reaction pathway of METH and to analyze the molecular interactions between METH and the MXene surface, providing key insights into the underlying molecular dynamics. The rich surface functionalities of MXene enable a favorable structural affinity with METH, facilitating enhanced interfacial interactions that promote oxidation kinetics and amplify electrochemical responses. The sensor demonstrates a linear response to METH across a concentration range from 2 ngmL −1 to 50 µg mL −1 , alongside satisfactory anti-interference performance and repeatability, rendering it appropriate for on-site preliminary screening of positive samples. Its successful validation in complex biological matrices confirms its broad applicability. By combining user-friendly operation with a rapid response, this method establishes a robust theoretical framework and a practical solution for the on-site screening of METH and related illicit substances.
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