ANALYTICAL BIOCHEMISTRY
·
2017
·
IF 2.334
Xuan Ni,Bing Xia,Lumei Wang,Jing Ye,Gaoshang Du,Haiwei Feng,Xiaotong Zhou,Tong Zhang,Wenhao Wang
In this paper, we developed a fluorescent aptasensor for 17β-estradiol (E2) determination in aqueous solution using label-free E2-specific aptamer, gold nanoparticles (AuNPs) and Rhodamine B (RhoB) as sensing probe, fluorescent quencher and fluorescent indicator respectively. In the absence of E2, AuNPs were wrapped by E2 aptamer and maintained dispersed in NaCl solution basically. These dispersed AuNPs could effectively impair the originally high fluorescence of RhoB. Contrarily, in the presence of E2, E2 aptamer could specifically combine with E2 to form E2-aptamer complex, so the AuNPs were released by E2 aptamer and aggregated under the influence of NaCl. The aggregated AuNPs have a weak influence on RhoB fluorescence. Therefore, the E2 concentration can be determined by the change of fluorescence intensity of RhoB. This fluorescent assay has a detection limit as low as 0.48 nM, a linear range from 0.48 to 200 nM, and high selectivity over other disrupting chemicals. It was applied to determine E2 in water samples with recoveries in the range of 94.3–111.7%. The fluorescent aptasensor holds great potential for E2 detection in environmental water samples.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
PROCESS SAFETY AND ENVIRONMENTAL PROTECTION
·
2024
·
IF 6.9
Jinyang Liu,Qiqi Liao,Chengcai Li,Xueliang Jiang,Jiuming Li,Wangyong Jin,Guojin Liu,Yuhai Guo,Bin Yu,Hailin Zhu
Being a low-energy, reusable, and environmentally friendly degradation technology, photocatalysis has excellent application prospects in textile dye wastewater degradation. In this study, we combine the advantages of photocatalysis and membrane technology to prepare photocatalytic membranes that immobilize the photocatalyst and alleviate membrane pollution. Dual-precursor graphitic carbon nitride (U6M1) was composited with Bi 12 TiO 20 (BTO) using the annealing method to prepare a novel Δ(Z + II)-type BTO/U6M1 photocatalyst with visible-light response capacity. Subsequently, BTO/U6M1/PES composite photocatalytic membranes were fabricated using the nonsolvent-induced phase separation (NIPS) method, and the photodegradation activity of the composite membranes was executed against rhodamine B (RhB) dye. The results indicated that the composite membrane exhibiting the best photocatalytic performance achieved nearly 100 % degradation of RhB within 120 min. Furthermore, the membrane with optimal photocatalytic performance retained photocatalytic activity for five consecutive dye degradation tests, demonstrating its reusability.
✓ 已验证
产品关联
DOI
高影响因子
Journal of Environmental Chemical Engineering
·
2024
·
IF 7.4
Jieli Ou,Yiqing Liu,Linyue Zhang,Zhenran Wang,Yuqi Tang,Yongsheng Fu,Dandan Zhao
Although Cu(II)/peroxymonosulfate (PMS) process has been successfully applied to degrade varied organic contaminants in water, the slow transformation of Cu(II) to Cu(I) that works only in alkaline conditions retards the treatment efficiency of this process. In this study, a new finding was observed, that is, oxytetraczdycline (OTC) could effectively enhance the degradation of organic pollutants in Cu(II)/PMS process where it was also removed in acidic conditions. With the addition of OTC in Cu(II)/PMS system, 85.5% of rhodamine B (RhB) was degraded in 90 min at pH 4.0, which was far more than that without OTC (36.1%), and simultaneously 98.1% of OTC was eliminated. The added OTC could form OTC-Cu(II) complexes which might powerfully improve the reduction of Cu(II) to Cu(I), exerting a positive effect on the PMS activation and subsequent degradation of RhB. Electron paramagnetic resonance (EPR) experiments assisted with radical scavenging experiments and Raman spectrum detection results suggested that Cu(III) and hydroxyl radical (HO • ) were the predominant reactive species for RhB degradation, while OTC removal in this system was mainly ascribed to direct PMS oxidation. The Cu(II)/PMS process also showed a promising success on the synergistic degradation of OTC with the other four refractory organic pollutants , indicating the potential application of PMS oxidation in water treatment .
✓ 已验证
产品关联
DOI
高影响因子
MOLECULES
·
2024
·Vol. 29
·期 4
·872
·
IF 4.2
Ying Zhao,Zhang-Gui Ding,Yu-Jie Yan,Rui Yang,Miao-Miao Qi,Shu-Kang Pan,Ji-Ling Xie,Yu-Hui Sun,Jin Xiang
Breast cancer is a significant threat to life and health, which needs more safe and effective drugs to be explored. Teadenol B is a characteristic chemical component of microbial fermented tea. This study discovered that teadenol B could exhibit obvious inhibitory effects on all four different clinical subtype characteristics of breast cancer cells. Proteomic studies show that deoxycytidine triphosphate deaminase (DCTD), which could block DNA synthesis and repair DNA damage, had the most significant and consistent reduction in all four types of breast cancer cells with the treatment of teadenol B. Considering MDA-MB-231 cells exhibit poor clinical prognosis and displayed substantial statistical differences in KEGG pathway enrichment analysis results, we investigated its impact on the size and growth of MDA-MB-231 triple-negative breast tumors transplanted into nude mice and demonstrated that teadenol B significantly suppressed tumor growth without affecting body weight significantly. Finally, we found that the conversion of LC3-I to LC3-II in MDA-MB-231 increased significantly with teadenol B treatment. This proved that teadenol B could be a strong autophagy promotor, which explained the down-regulation of DCTD to some extent and may be the potential mechanism underlying teadenol B’s anti-breast cancer effects. This finding provides new evidence for drinking fermented tea to prevent breast cancer and highlights the potential of teadenol B as a novel therapeutic option for breast cancer prevention and treatment, necessitating further investigations to clarify its exact target and the details involved.Keywords:teadenol B;breast cancer;autophagy
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL PHYSICS LETTERS
·
2025
·
IF 3.1
Yingtong Pan,Yiwen Tang,Ji-Xuan Liu,Guo-Jun Zhang
High-entropy engineering offers a new paradigm for catalyst design. In this study, a high-entropy BiFeO 3 -based catalyst was synthesized via rare-earth multi-element doping. Entropy engineering enhanced structural stability and oxygen vacancy concentration, which promoted iron redox cycling and the generation of reactive oxygen species, thereby boosting activity in Fenton reactions. The catalyst achieved 96.9 % rhodamine B degradation within 20 min ( k = 0.169 min −1 ) under neutral conditions. It retained 93.5 % activity after multiple cycles without ion leaching, demonstrating excellent stability, scalability, and durability. This work confirms the feasibility of high-entropy strategies in developing efficient and sustainable catalysts for water treatment applications.
✓ 已验证
产品关联
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2025
·
IF 5.4
Qing Yuan,Yi He,Yi Sun,Xiangshan Hou,Shijun Xu,Han Liu,Kaijun Wei,Xingtao Cheng,Quangang Chen,Yi Fan
In this study, a two-phase superhydrophobic nanocomposite coating was prepared by combining electroless deposition and electrodeposition methods. Firstly, the Ni-B /TiC coating were prepared on the metal surface by electroless deposition. Then, the low surface energy cerium myristic acid coatings (Ce [CH 3 (CH 2 ) 12 COO] 3 ) were further prepared on the coating surface by electrodeposition. The test results showed that the two-phase composite coating with Ce [CH 3 (CH 2 ) 12 COO] 3 deposited on the Ni-B/TiC coating (Ni-B/TiC@MACe) had excellent nonwetting properties (water contact angle of 160.1° and rolling angle of 4.3°) and self-cleaning properties. The coating exhibited excellent stability and durability, retaining its superhydrophobicity even after 12 months of exposure to air. Notably, this performance was less affected by pH fluctuations. In addition, mechanical robustness was verified by 50 tape stripping cycles in which the superhydrophobic surface maintained a water contact angle of over 150°. The test results of corrosion resistance showed that the Ni-B/TiC@MACe coating has excellent corrosion resistance with a corrosion inhibition rate of 99.95 %, and the impedance modulus was three orders of magnitude higher than that of the Ni-B coating. In addition, the coating provided protection under simulated acidic conditions with a corrosion potential of - 0.27 V. In a long-term immersion test, the coating impedance modulus remained at 10 6 after seven days of immersion, which effectively protected the underlying metal from corrosion-induced damage. Therefore, the superhydrophobic coating in this study is expected to provide new ideas for the design of new anti-corrosion coatings.
✓ 已验证
产品关联
DOI
高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2025
·
IF 0
Wu Guizhi,Duan Xuebin,Xu Hongqing,Han Chunyu,Liu Jing,Yan Boyin,Li Jincheng,Wang Jianming,Wang Songxue
The UV/SPC process was employed for the removal of rhodamine B (RhB), and the influences of reaction parameters and natural water components on the degradation of RhB were systematically studied. The results demonstrate that RhB can be efficiently eliminated in the UV/SPC system compared to using UV photolysis or SPC oxidation alone, with •OH and CO 3 •− being the main radicals to degrade RhB. The degradation efficiency of RhB was enhanced with increasing SPC concentration but decreased with increasing initial RhB concentration. Moreover, the degradation efficiency of RhB decreased with the increasing initial pH. When pH increased from 3 to 11, the degradation efficiency of RhB declined from nearly 100 to 81.93% within 20 min. Natural organic matter (NOM) and anions (Cl − and HCO 3 − ) exhibited an inhibitory effect on the degradation of RhB in the UV/SPC system, and the inhibitory effect was aggravated with the increase of NOM and anion concentrations. Consequently, there was a decrease in the degradation efficiency of RhB in the UV/SPC system in real water compared to pure water. The byproducts generated during the degradation of RhB were attributed to hydroxylation, N -deethylation, and C-O bond cleavage. Some intermediate products from RhB degradation still pose relatively high environmental risks, while most have low environmental hazards.
✓ 已验证
产品关联
DOI
PubMed
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Yongbin Qin,Jun Guan,Dan Xu,Chengyin Wang,Jun Sun,Zichen Zheng,Wei Gu,Kewei Liu,Carla Bittencourt,Lifeng Zhang
Alpha-Fetoprotein (AFP) is an important tumor biomarker closely associated with the early diagnosis of hepatocellular carcinoma and other diseases. To achieve rapid and highly sensitive AFP detection, this study developed a label-free electrochemical impedance immunosensor with enhanced sensitivity based on Polystyrene- block -poly acrylic acid (PS-b-PAA) thin films and a biotin-streptavidin (B-SA) amplification strategy. The sensor utilizes the unique properties of PS-b-PAA thin films, where carboxyl groups (-COOH) form covalent bonds with the amino groups (−NH 2 ) of streptavidin, combined with the B-SA system to achieve efficient antibody immobilization. The results showed that the B-SA system significantly enhanced antibody immobilization efficiency, reduced non-specific adsorption, and improved the sensitivity and specificity of electrochemical signals. As a signal amplification strategy, the biotin-streptavidin system increased the sensing signal by approximately 2.19-fold. The sensor exhibited a linear response range from 0.05 ng/mL to 300.00 ng/mL and a detection limit of 0.02 ng/mL. Moreover, the sensor's performance in real human serum samples was consistent with that of the enzyme-linked immunosorbent assay (ELISA), demonstrating excellent reproducibility and long-term stability. This study shows that the fabricated electrochemical impedance immunosensor, based on PS-b-PAA thin films and the B-SA system, exhibits excellent performance in AFP detection, providing a reliable, rapid, and efficient solution for early cancer biomarker detection.
✓ 已验证
产品关联
DOI
高影响因子
EUROPEAN POLYMER JOURNAL
·
2025
·
IF 6.3
Yan Wang,Jie Zhang,Jianlei Lu,Nan Hai,Jiawei Zhang
In this study, we developed a poly(styrene- b - N -isopropyl acrylamide) (PS- b -PNIPAm) block copolymer-incorporated hydrogel with cooling/water dual-responsive shape recovery performance. Three kinds of PS- b -PNIPAm block copolymers with different chain lengths of PNIPAm were prepared by reversible addition-fragmentation chain transfer (RAFT) polymerization, and the block copolymers could self-assemble into micelles with PNIPAm as the outer layer in water. Hydrogels were then prepared by introducing the micelles formed by the block copolymers into the polyacrylamide (PAM) network. The collapse of PNIPAm chains could be promoted by both temperature and salt, which acted as temporary crosslinks to stabilize temporary shapes, enabling cooling- and water-stimulated shape recovery. Moreover, fluorescent information could be encoded on the surface of the hydrogel and encrypted by the shape changes of the hydrogel during the shape fixing process, with the information revealed under UV irradiation after the shape recovery process, achieving information security. This approach could accelerate the evolution of shape memory hydrogels and broaden their applications across diverse fields.
✓ 已验证
产品关联
DOI
高影响因子
Journal of Inorganic and Organometallic Polymers and Materials
·
2025
·
IF 4.9
Wang Chiyuan,Long Xin,Shao Changwei,Huang Jiawei,Ren Jiaqi
Si–B–N–O ceramics are promising materials for wave-transparent windows of hypersonic vehicles due to the excellent thermal stability and low dielectric constant. The polymer-derived ceramics (PDC) route is widely adopted for flexible compositional control of the Si–B–N–O covalent ceramics. In this study, a novel borazine-modified polysilazoxane (RBOSZ) was synthesized using trichlorosilane, tert -butanol, trichloroborazine, and ammonia as starting materials. RBOSZ features a Si–N–Si backbone and borazine rings. The Si–B–N–O ceramic was derived from RBOSZ with a ceramic yield of 61 wt% after pyrolysis under nitrogen atmosphere. Boron facilitates the formation of Si 2 N 2 O nanograins at elevated temperatures and enhances the ceramic’s high-temperature stability. By switching nitrogen to ammonia during organic-inorganic transformation, a low-carbon Si–B–N–O ceramic was obtained and retained its amorphous structure up to 1400 °C. After annealing at 1600 °C, Si 2 N 2 O/β-Si 3 N 4 nanocrystals participated in the Si–B–N–O matrix. This work establishes a facile precursor for high-performance Si–B–N–O ceramics to meet the application demands of heat-resistant wave-transparent windows.
✓ 已验证
产品关联
DOI
高影响因子
ENVIRONMENTAL POLLUTION
·
2025
·
IF 7.3
Qi Huang,Xiaohu Jin,Zirui Hu,Ziwen Zhong,Yitao Cai,Qian Yao,Xiaofei Li,Xueqin Tao,Zhi Dang,Guining Lu
Antimony (Sb) pollution is becoming a non-negligible issue due to its toxic and carcinogenic properties. In mining areas, jarosite is a main host mineral for Sb(V), and its transformation may seriously influence the fate of Sb. In this study, we examined the transformation of Sb(V)-coprecipitated jarosite in the presence of oxalic acid (OA) and Desferrioxamine B (DFOB), and explored the resulting repartition of Sb. Results showed that OA and DFOB retarded jarosite dissolution but promoted Fe(III) and Sb(V) release, playing a combined role in this retardation and promotion. In treatment without OA or DFOB, jarosite transformed into hematite and goethite. In DFOB-only systems, DFOB did not change the jarosite transformation pathway; goethite and hematite were still the dominant products, and aqueous Fe(III)-DFOB complexes were formed. In OA-only systems, the re-adsorption of aqueous Fe(III)-OA complexes on the mineral surface may result in another recrystallization pathway, forming goethite. In OA-DFOB systems, DFOB competed with OA for Fe(III), forming Fe(III)-DFOB complexes and delayed OA-induced jarosite transformation into goethite. By the end of all reactions, more than 99.94 % of total Sb was retained by neo-formed secondary Fe(III) minerals. OA drove more Sb to become phosphate-extractable, and DFOB drove the above phosphate-extractable Sb into poorly crystalline phases or residual phases.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Scientific Reports
·
2017
·Vol. 7
·期 1
·1-5
·
IF 4.259
Wang Xu-Ping,Zhou Peng-Fei,Li Zhi-Gang,Yang Bo,Hollmann Frank,Wang Yong-Hua
A Ser105Ala mutant of the lipase B from Candida antarctica enables ‘perhydrolase-only’ reactions. At the example of the chemoenzymatic Baeyer-Villiger oxidation of cyclohexanone, we demonstrate that with this mutant selective oxidation can be achieved in deep eutectic solvent while essentially eliminating the undesired hydrolysis reaction of the product.
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）