STARCH-STARKE
·
2022
·
IF 2.688
Mengyu Zhang,Wenshuai Wang,Wenxue Sun,Jianjun Zhang,Le Jia
This study investigates the efficacy of chewable tablets made from the Pleurotus djamor zinc polysaccharide (PCT-Zn) against the nonylphenol (NPs) induced male reproductive damage in mice. The trial takes the form of constructing a model by infusing NPs into mice, followed by treatment with PCT-Zn solution infusion 1 h later, for a total of 8 weeks. It is found that PCT-Zn shows potential effects on increasing the testicular coefficients, enhancing the antioxidant activities, and inhibiting the apoptotic and inflammatory responses, which indicate that PCT-Zn has the effect of alleviating the NPs-induced reproductive damage. The results of the experiment suggest that the P. djamor zinc polysaccharide can be used as a dietary supplement to develop appropriate products to alleviate reproductive damage caused by environmental pollutants.
研究领域:
环境毒理学
·
生殖生物学
·
药理学
·
营养科学
✓ 已验证
产品关联
DOI
高影响因子
STARCH-STARKE
·
2021
·
IF 2.741
Hui Yang,Rihui Lin,Yanye Fan,Sai Jiang,Yujiao Lin
The rosin acid starch (RAS) is prepared under the catalysis of lipase, by esterification on the starch particles' surface in a two-phase reaction system, using rosin acid and native cassava starch as starting materials. The effects of reaction time, solvent types, substrate ratio, reaction temperature, and lipase dosage on the degree of substitution (DS) of RAS are investigated. Based on the single factor experiments, the reaction conditions are optimized according to the principle of the combination Box-behnken centered design and response surface methodology analysis. The mathematical model of the influence of reaction temperature, material ratio, and enzyme addition amount on DS is established. The optimum synthesis conditions are determined as follows: solvent, trichloromethane; reaction time, 10 h; reaction temperature, 59 °C; substrate ratio (m Rosin acid :m starch) , 4.1; and lipase dosage, 264 µL. Under these conditions, it is found that the DS is 0.0608. The analysis of variance and verification experiments show that the mathematical model has good fit degree and high credibility. Compared with the native cassava starch, RAS has improved contact angle, emulsion capacity, and emulsion stability.
研究领域:
食品科学
·
生物化学
✓ 已验证
产品关联
DOI
高影响因子
STARCH-STARKE
·
2021
·
IF 2.741
Dan Qin,Jun Wu,Yuxiang Zhang,Mian Bao,Xiaoyue Du,Hongqing Sang,Zhengyou Wei
This study experimentally investigates the effect of changes in amylose-to-amylopectin ratio on the multi-scale structures, hydrophilicity, and thermal properties of starch–chitosan essential oil (EO) films incorporated with vanillin. The results indicate that aggregates and uneven structures tend to form in the EO films with a higher proportion of amylose. In Fourier transform infrared spectroscopy, as the chitosan content increases, the wavenumber of stretching vibration of hydroxyl and the bending vibration of amino groups decrease, while the wavenumber of stretching vibration of C-O increases. Furthermore, with an increase in the chitosan content, the changes in the starch–chitosan EO film structure impacts the hydrophilic trend, and the hydrophilic changes in the EO films with common starch and G80 starch are significant changes with the proportions of starch to chitosan from 7:3 to 5:5. When their mass ratio is 3:7, the starch–chitosan EO films investigated exhibit the lowest decomposition peak temperature.
研究领域:
食品科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
STARCH-STARKE
·
2021
·
IF 2.741
Qifeng Chen,Yunjia Wang,Fushou Yin,Wenxiong Wang,Guangxue Chen,Peisheng Lin
Medical dressings require good antibacterial and mechanical properties. Polyvinyl alcohol based medical dressings are commercially available, and the antimicrobial properties of chitosan and cerium ions are known, and nanocellulose possesses excellent comprehensive properties, such as non-toxicity, biocompatibility, and biodegradability. In this study, polyvinyl alcohol-chitosan/cerium-nanocellulose (PVA-Cs/Ce-CNF) composite hydrogels are prepared by a freeze-thaw method and characterized by scanning electron microscope and X-ray diffraction. It is expected to improve antibacterial activity of the composite hydrogels by adding a small amount of cerium, and their biological activity will not be affected. In addition, the effects of chitosan/cerium (Cs/Ce) complexes and nanocellulose with different contents on properties are investigated. The results show that PVA-Cs/Ce-CNF composite hydrogels have a 3D, highly porous structure with distributed pores of 8–30µm, good skin viscosity, efficient ability to absorb fluid, and suitable water vapor transmission rate of 2000—2500 g m −2 day −1 . Two hydrogels in specific ratio show good strong tensile strength of 132.6 and 130.1 kPa respectively, and their elongation at break are over 400%. The PVA-Cs/Ce-CNF composite hydrogels are non-toxic, and they have inhibitory effect on Escherichia coli and Staphylococcus aureus . These results suggest that the PVA-Cs/Ce-CNF composite hydrogels have great potential as medical dressings.
研究领域:
材料科学
·
生物医学工程
·
药学
✓ 已验证
产品关联
DOI
高影响因子
STARCH-STARKE
·
2022
·
IF 2.688
Shan Gao,Junyi Wang,Yongze Zhang,Nuaner Liu,Rui Zhang,Zhongquan Sui,Hanxue Hou
Hull-less barley grass polysaccharide extracts (HBP) are prepared, and the physicochemical and antioxidant properties of agar films with different HBP contents (0, 0.5, 1, 1.5, and 2% w/w of agar mass) are investigated. Infrared spectroscopy shows that HBP interacts with the agar matrix via intermolecular hydrogen bonds. The incorporation of HBP causes rougher surface morphology with increased film thickness ( p < 0.05). The films with HBP exhibit decreased brightness with a greenish and yellowish hue. The flexibility of the films is improved gradually as HBP contents increase from 0 to 1.5% w/w ( p < 0.05), however, a slight reduction is observed with 2% w/w HBP addition ( p > 0.05). The water resistance and surface hydrophobicity of the films are enhanced by adding HBP ( p < 0.05). The antioxidant test reveals the strong antioxidant capacity of the HBP-loaded films, which is positively correlated with the HBP contents ( p < 0.05), with 2% w/w HBP leading to 59.28% DPPH radical scavenging and 69.00% ABTS radical scavenging. Results suggest that HBP is a promising functional agent for developing antioxidant biopolymer films, and the agar/HBP edible films prepared in this study have potential in food packaging fields.
研究领域:
食品科学
·
材料科学
✓ 已验证
DOI
高影响因子
STARCH-STARKE
·
2023
·
IF 2.3
Yijuan Xu,Weifeng Hua,Haoran Xu,Harold Corke,Wuyang Huang,Zhongquan Sui
Hulless barley (HB) grass is a potential resource of functional food. In this study, the proliferation inhibitory effect against cancer cells of an alkaline extracted polysaccharide (APP) from HB grass (HBG) is analyzed. The yield of crude alkaline extracted polysaccharide (APC) reaches 15.1%. After purification, the purity and polydispersity index (PDI) of the APP are 98.3% and 1.38, respectively. The molecular weight of APP is 5.1 × 10 5 Da, whereas the number-average molecular weight of APP is 3.7 × 10 5 Da. APP is composed of arabinose (37.8%), xylose (41.3%), glucose (4.6%), and galactose (16.3%). According to the infrared spectral analysis, APP is found to contain β-glycosidic bonds. Moreover, APP possesses significant cell proliferation inhibitory effects against various cancer cell lines, such as 4T1, HT29, Caco-2, and CT26.WT in a dose-dependent manner. Notably, the IC50 value of 4T1 reaches 7.56 mg mL −1 , which indicates that APP from HBG has a potential anti-cancer effect in vitro. It may be further investigated as an ingredient or nutraceutical for development and utilization in functional foods to prevent or treat cancer and related diseases.
研究领域:
食品科学
·
癌症研究
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药理学
·
植物化学
✓ 已验证
产品关联
DOI
高影响因子
STARCH-STARKE
·
2023
·
IF 2.3
Yao Wen,Caimei Su
A Box–Behnken design (BBD) of response surface methodology (RSM) is employed to further optimize ultrasonic-assisted extraction conditions for Ophiopogon japonicus polysaccharides. The results show that optimized extraction conditions are liquid–solid ratio of 22:1 mL g −1 , ultrasonic time of 27 min, and ultrasonic power of 200 W. Under these conditions, the mean experimental value of extraction yield (39.49%) is achieved, which is 1.33 times that of distilled water leaching extraction (29.68%). In addition, one of the eluting fractions, SPs-1 , has high α -glucosidase and α -amylase inhibitory activities as well as 1,1-Diphenyl-2-picrylhdrazyl radical and α-glucosidase, 2,2’-Azino-bis (3-ethylbenzthiazoline-6-sulfonic acid) cation scavenging activities with an IC 50 value of 0.060, 0.021, 0.50, and 0.10 mg mL −1 . Therefore, SPs-1 from O. japonicus can be considered as multifunctional biological ingredients to be used in anti-hyperglycemic pharmaceutical formulation and antioxidant in functional foods.
研究领域:
药学
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食品科学
·
生物化学
✓ 已验证
产品关联
DOI
高影响因子
STARCH-STARKE
·
2023
·
IF 2.3
Yunchun Wang,Zeyu Wu,Yanting Lin,Ailing Hui,Han Tao,Alia Shah,Qingsong Liu,Jianwen Li,Shengnan Li,Hao Liu,Wencheng Zhang
In this study, the effects of chain length distribution and drying methods on the structural properties and in vitro digestibility of resistant starch (RS) are investigated. Rice starch is debranched at 10% w/w solid concentrations, incubated at 60 °C, and further subjected to freeze drying and oven drying treatment to obtain debranched starch (DBS). The chain length distribution shows that DBS (the degree of polymerization [DP] = 19.52 ± 0.13) has a high proportion of B1 and B2 chains (DP13-36) and a narrow chain length distribution. In addition, the results of scanning electron microscopy (SEM) show that the oven-dried samples have denser structures and larger particle morphology compared to samples prepared by freeze-drying. In FTIR, LCM-Raman and X-ray diffraction patterns, debranched starch supernatant fraction 1 (DBSS1) exhibit higher short-range molecular order and crystallinity than other samples. Digestibility analysis shows that DBSS1 with narrow chain length distribution (DP13-36) promotes the high content of RS formation and oven drying is more favorable for RS formation than freeze drying (RS DBSFS1 = 79.69 ± 5.09% and RS DBSOS1 = 84.17 ± 0.17%). This suggests that the proper narrow chain length distribution is conducive to the formation of ordered structure and an increase in resistance. Oven drying provides a larger starch particle size, which facilitates resistance to digestion.
研究领域:
食品科学
·
淀粉化学
·
营养学
✓ 已验证
产品关联
DOI
高影响因子
STARCH-STARKE
·
2023
·
IF 2.3
Min Zhu,Jieyi Xiong,Shanshan Li,Qifeng Chen
Carbon quantum dots (CQDs) are one of the most promising luminescent nanomaterials for anti-counterfeiting due to their excellent optical properties, low toxicity, and environmental friendliness. With the development of green chemistry, biomass carbon sources have attracted attention. Herein, nitrogen-doped carbon quantum dots (N-CQDs) are synthesized using waste corn bract nanocellulose as the carbon source and L-histidine as the nitrogen source in a simple and quick one-step microwave method. It is found that a raw material mass ratio of 1:4, a temperature of 100 °C, and a preparation time of 5 min are the optimum preparation conditions. The fluorescence quantum yield of N-CQDs obtained under these conditions is 32.64%. Under the excitation of light at a wavelength of 365 nm, the emission peak of N-CQDs is located at 430 nm and emits blue light. This study also provides a method to prepare fluorescent anti-counterfeiting films with excellent performance and fluorescent detection probes solely from waste biomass corn bract leaves and L-histidine.
研究领域:
材料科学
·
绿色化学
·
光学材料
✓ 已验证
产品关联
DOI
高影响因子
STARCH-STARKE
·
2023
·
IF 2.3
Yongjie Lin,Yan Lin,Zhiyun Wang,Yanbo Wang,Yi Zhang,Baodong Zheng,Hongliang Zeng
The objectives of this study are to investigate the structural and physicochemical properties of a novel acetylated lotus seed starch (LSA). LSA is successfully prepared using an aqueous phase method. Fourier transform infrared spectroscopy (FTIR) proves that a carbonyl C=O vibration at 1737 cm −1 are due to the introduced acetyl groups. X-ray diffraction (XRD) indicates that the acetylation treatment does not change the crystal structure, but reduces the relative crystallinity of starch. Scanning electron microscopy (SEM) shows that the surface of LSA with 12% of acetic anhydride (LS-12A) becomes the roughest. Moreover, compared with lotus seed starch (LS), the particle size, transparency, swelling power, and solubility of LSA are increased to 18.01 ± 0.66 µm, 15.30% ± 0.30%, 9.59 ± 1.78 g g −1 , and 6.06% ± 0.99% at 55 °C with the additional content of acetic anhydride. However, differential scanning calorimetry (DSC) shows that the melting enthalpy of LSA decreases compared with LS. This work provides some theoretical basis for the study and development of acetylated starch.
研究领域:
食品科学
·
生物化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
·
2011
·
IF 3.044
Jundong Zhu,Zhichao Zhou,Cuihong Yang,Deling Kong,Ying Wan,Zheng Wang
Folate (FA)-conjugated star-shaped copolymer was prepared as a targeted carrier for anticancer drug delivery by ring-opening polymerization of L -lactide using pentaerythritol (PTL) as an initiator, followed by conjugation with methoxy poly(ethylene glycol) (MPEG) and FA-poly(ethylene glycol) (FA-PEG). The resulting amphiphilic star-shaped copolymer was shaped into drug-loaded micelles, and the achieved micelles had an average size of around 146 nm in diameter. It was found that the sustained release time of model drug (indomethacin, IMC) from some selected micelles could reach around 40 h. In comparison with linear poly( L -lactic acid)-block-methoxy poly(ethylene glycol) copolymer (PLA-MPEG), the stability of the star-shaped pentaerythritol- co -poly( L -lactic acid)-block-[methoxy poly(ethylene glycol) and FA-poly(ethylene glycol)] (PTL-PLA-MPEG/PEG-FA) micelle was significantly improved because of the lower critical micelle concentration (CMC). The specificity of PTL-PLA-MPEG/PEG-FA targeting cancer cells was demonstrated by intracellular uptake of PTL-PLA-MPEG/PEG-FA and PTL-PLA-MPEG using HeLa human cervical cancer cells. After 2 h in vitro incubation, a significant intracellular uptake for PTL-PLA-MPEG/PEG-FA over PTL-PLA-MPEG was observed by using inverted fluorescence microscope and flow cytometry. These results suggested that PTL-PLA-MPEG/PEG-FA polymeric micelle could be a potentially useful carrier for delivering selected drugs to FA-receptor positive cancer cells. © 2011 Wiley Periodicals, Inc. J Biomed Mater Res Part A:, 2011.
研究领域:
生物材料
·
药剂学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nanomaterials
·
2019
·Vol. 9
·期 4
·547
·
IF 4.034
Meng Li,Jian-Wei Guo,Wei-Qiu Wen,Jem-Kun Chen
A typical amphiphilic star polymer adamantane-[poly(lactic-co-glycolic acid)-bis(2-carboxyethyl) sulfide-poly(ethylene glycol) monomethyl ether)]4with a specific hydrophilic/redox-sensitive/hydrophobic structure was designed and synthesized through ring opening and esterification reactions. The self-assembled nanomicelles were used as doxorubicin (DOX) delivery vehicles with suitable critical micelle concentrations (5.0 mg/L). After the drug being loaded, drug-loaded micelles showed good drug-loading efficiency (10.39%), encapsulation efficiency (58.1%), and drug release (up to 60%) under simulated biological environment conditions. In addition, the backbone structure of the biodegradable polymer was easily hydrolyzed by the action of biological enzymes. As expected, cell-based studies showed that the designed polymer micelles possessed good biocompatibility (a survival rate of 85% for NH-3T3 cells). Moreover, the drug (DOX) still maintained good anti-cancer effects after being loaded, which caused 40% of MCF-7 cells to survive. These redox-sensitive micelles showed anti-tumor therapeutic potential.
研究领域:
药剂学
·
肿瘤学
·
材料科学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）