计算溶液所需的质量、体积或浓度。
Maleimide-DTPA (MDTPA) 是以马来酰亚胺基团为肽结合位点的单反应性 DTPA 衍生物 (MDTPA),能够与放射性核素结合,制备核素偶联物 (RDC)。Maleimide-DTPA 能够螯合铟-111 (111In),而对多肽和肽进行铟-111 标记。例如,结合 OST7,在人血清中孵育具有高稳定性,稳定性好于环状 cDTPA。Maleimide-DTPA 是应用于医疗成像或治疗的良好材料。
Maleimide-DTPA (MDTPA) is a monoreactive DTPA derivative (MDTPA) with maleimide group as peptide binding site, which can be combined with radionuclides to prepare radionuclide conjugates (RDC). Maleimide-DTPA can chelate indium-111 (111In) and label peptides and peptides with indium-111. For example, it has high stability when combined with OST7 incubated in human serum, which is better than cyclic cDTPA. Maleimide-DTPA is a good material for medical imaging or treatment.