来自霍乱弧菌的神经氨酸苷酶已在一项研究中使用,以评估其在易感细胞结合和摄取霍乱毒素中的作用。它还已在另一项研究中使用,以研究钠底物的制备及其在神经氨酸酶荧光测定中的应用。 神经氨酸酶被用作糖缀合物分布和底物特异性研究的细胞表面探针。应用:
神经氨酸酶是糖苷水解酶,催化末端唾液酸残基的水解。最知名的莫过于促进流感病毒释放的病毒近酰胺酶。
Neuraminidase enzymes are glycoside hydrolase enzymes that catalyze hydrolysis of terminal sialic acid residues. The most well-known are the viral nearamidases, which promote influenza virus release.
Application:
Neuraminidase from Vibrio cholerae has been used in a study to assess its role in the binding and uptake of cholera toxin by susceptible cells. It has also been used in a study to investigate the preparation of a sodium substrate and its use in a fluorometric assay of neuraminidase.
Neurminidase is used as a cell-surface probe for glycoconjugate distribution and in substrate specificity studies.