ActiBioPure™,His标签,无动物源,无叠氮钠,无载体,生物活性 级 提供 ≥95%(SDS-PAGE) 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。
-20°C储存,避免反复冻融。超低温运输 。请查阅批次 COA 获取详细规格。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Purity
≥95% (SDS-PAGE)
Endotoxin level
＜0.1 EU/μg
Function
Angiopoietin-like 7 (ANGPTL7), also known as Corneal-Derived Transcript 6 (CDT6), is a secreted glycoprotein that is structurally related to the angiopoietins. Members of this protein family contain an N-terminal coiled coil domain and a C-terminal fibrinogen-like domain . ANGPTL7 shares 89% aa sequence identity with mouse and rat ANGPTL7. It is secreted as a 45 ‑ 50 kDa monomer that forms disulfide-linked homotrimers and tetramers via the coiled coil domain . ANGPTL7 is expressed in the corneal stroma, trabecular meshwork, and sclera and is elevated in glaucoma aqueous humor . Its production is up‑regulated in trabecular meshwork cells by glucocorticoids and TGF-beta and in cartilage by TNF-alpha. Overexpression of ANGPTL7 in trabecular meshwork cells inhibits the production of collagen and proteoglycans . When overexpressed in tumor cells it promotes collagen and proteoglycan deposition but inhibits tumor xenograft progression and tumor angiogenesis . Recently, ANGPTL proteins, including ANGPTL-2, -3, -4, -5 and -7, are identified as growth factors in combination with SCF, Thrombopoietin, IGF-II and FGF acidic that enhance the expansion and engraftment of human and mouse hematopoietic stem cells."
Recombinant Human Angiopoietin-like 7/ANGPTL7 Protein (rp142833) - Protein Bioactivity
When Recombinant Human LILRB1/CD85j/ILT2 Protein (rp148284) is coated at 4.0 µg/mL, Biotinylated Recombinant Human Angiopoietin-like 7/ANGPTL7 Protein (rp142833) binds with the ED
₅₀
of 2.0 μg/mL.
Recombinant Human Angiopoietin-like 7/ANGPTL7 Protein (rp142833) - SDS-PAGE
3 μg/lane of Recombinant Human Angiopoietin-like 7/ANGPTL7 Protein was resolved with SDS-PAGE under reducing (R) condition and visualized by Coomassie® Blue staining, showing the band at 34 - 35 kDa & 45 - 50 kDa under reducing condition.
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ24F0606783 |
分析证书 | rp142833 |
| ZJ24F0606784 |
分析证书 | rp142833 |
| ZJ24F0606785 |
分析证书 | rp142833 |
| ZJ24F1215049 |
分析证书 | rp142833 |
| ZJ24F1215050 |
分析证书 | rp142833 |
| ZJ24F1215051 |
分析证书 | rp142833 |
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