Purity ≥95% (SDS-PAGE) Endotoxin level <0.1 EU/μg Function Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20~-80℃ 下可保存 1 年以上。收货后建议分装。避免冷冻/解冻循环。
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Recombinant Human CD22 Protein (rp143882) - Protein Bioactivity Immobilized Recombinant Human CD22 Protein (rp143882) at 1 μg/mL can bind Recombinant CD22 Antibody (Ab094265) with a EC₅₀ is 4.6 ng/mL.
Recombinant Human CD22 Protein (rp143882) - SDS-PAGE 2 μg/lane of Recombinant Human CD22 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 130-150 kDa under reducing conditions and 130-150 & 260-300 kDa under non-reducing conditions.