Measured by the ability of the immobilized protein to support the adhesion of Jurkat human acute T cell leukemia cells. When 5×10^4 cells/well are added to Recombinant Human CD6 Protein (rp144066) coated plates (2 μg/mL and 100 μL/well) in the presence of 10 μg/mL PHA, approximately > 50% cells will adhere specifically after 60 minutes at 37℃.
Function Cell adhesion molecule that mediates cell-cell contacts and regulates T-cell responses via its interaction with ALCAM/CD166. Contributes to signaling cascades triggered by activation of the TCR/CD3 complex. Functions as a costimulatory molecule; promotes T-cell activation and proliferation. Contributes to the formation and maturation of the immunological synapse. Functions as a calcium-dependent pattern receptor that binds and aggregates both Gram-positive and Gram-negative bacteria. Binds both lipopolysaccharide (LPS) from Gram-negative bacteria and lipoteichoic acid from Gram-positive bacteria. LPS binding leads to the activation of signaling cascades and down-stream MAP kinases. Mediates activation of the inflammatory response and the secretion of pro-inflammatory cytokines in response to LPS.
Measured by the ability of the immobilized protein to support the adhesion of Jurkat human acute T cell leukemia cells. When 5×10^4 cells/well are added to Recombinant Human CD6 Protein (rp144066) coated plates (2 μg/mL and 100 μL/well) in the presence of 10 μg/mL PHA, approximately > 50% cells will adhere specifically after 60 minutes at 37℃.
65 - 90 kDa, under reducing conditions; 65 - 90 kDa, under non-reducing conditions
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH 7.4
复溶
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20~-80℃ 下可保存 1 年以上。收货后建议分装。避免冷冻/解冻循环。
图片
Recombinant Human CD6 Protein (rp144066) - Protein Bioactivity Measured by the ability of the immobilized protein to support the adhesion of Jurkat human acute T cell leukemia cells. When 5×10^4 cells/well are added to Recombinant Human CD6 Protein (rp144066) coated plates (2 μg/mL and 100 μL/well) in the presence of 10 μg/mL PHA, approximately > 50% cells will adhere specifically after 60 minutes at 37℃.
Recombinant Human CD6 Protein (rp144066) - SDS-PAGE 3 μg/lane of Recombinant Human CD6 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 65 - 90 kDa.
ZJ25F0217649
危险品化学品经营许可证（带存储）