Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood eosinophils is in a concentration range of 0.1-10.0 ng/ml.
> 97 % by SDS-PAGE and HPLC analyses.Endotoxin level is <1 EU/μg
Function
Human CCL11 is belonging to the CC chemokine family. It is encoded by the gene CCL11. CCL11 was first purified from bronchoalveolar lavage fluid of guinea pigs. It was a strong and specific eosinophil chemoattractant in vitro. It can directly chemotactic for eosinophils, but not for monocytes or neutrophils. CCR3 has been identified to be a specific CCL11 receptor.In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions.
规格
产品名称
Recombinant Human CCL11/Eotaxin Protein
别名
重组人嗜酸粒细胞趋化因子 | 重组人 CCL11/Eotaxin 蛋白
英文别名
C-C motif chemokine 11 | CCL11 | chemokine (C-C motif) ligand 11 | Eosinophil chemotactic protein | Eotaxin | eotaxin-1 | MGC22554 | SCYA11Small-inducible cytokine A11 | small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin) | SCYA11 | C-C mo
Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood eosinophils is in a concentration range of 0.1-10.0 ng/ml.
Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, pH 7.4, 150 mM NaCl.
复溶
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃. Further dilutions should be made in appropriate buffered solutions.
Recombinant Human CCL11/Eotaxin Protein (rp145581)-Protein Bioactivity Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood eosinophils is in a concentration range of 0.1-10.0 ng/mL.
Recombinant Human CCL11/Eotaxin Protein (rp145581)-SDS-PAGE Recombinant Human CCL11/Eotaxin Protein was resolved with SDS-PAGE under reducing (R) and visualized by Coomassie® Blue staining, showing a single band at 9.2 kDa.