Essential for cartilage morphogenesis and joint formation. Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.
Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH7.4.
复溶
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20~-80℃ 下可保存 1 年以上。收货后建议分装。避免冷冻/解冻循环。
图片
Recombinant Human Noggin Protein (rp149360) - Binding Activity Immobilized Recombinant Human BMP2 Protein at 2 μg/mL can bind Recombinant Human Noggin Protein (rp149360) with a EC50 of 44 ng/mL.
Recombinant Human Noggin Protein (rp149360) - SDS-PAGE 2 μg/lane of Recombinant Human Noggin Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 30 kDa under reducing condition and 80 - 100 kDa under non-reducing condition. Noggin protein has an unusual migration in non-reduced SDS-PAGE due to the non-covalent dimer which is the active protein. Similar migration in SDS-PAGE is seen for Gremlin-1, a related BMP antagonist.