1、Measured by its ability to induce apoptosis in Jurkat cells (Human T Lymphocyte Cells). The ED50 for this effect is typically <12ng/mL. 2、Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D (A113142). The ED50 for this effect is 1.84 ng/mL.
Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.
1、Measured by its ability to induce apoptosis in Jurkat cells (Human T Lymphocyte Cells). The ED50 for this effect is typically <12ng/mL. 2、Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D (A113142). The ED50 for this effect is 1.84 ng/mL.
Lyophilized from a sterile solution containing 20 mM phosphate buffer, pH7.4
复溶
After receiving lyophilized powder protein, centrifuge first, and then redissolve with deionized water to the purposed concentration.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在适当的储存和处理条件下,自收到产品之日起 12 个月内保持稳定。避免反复冻融循环。
图片
Recombinant Human TRAIL Protein (rp152616)-Protein Bioactivity Measured by its ability to induce apoptosis in Jurkat cells (Human T Lymphocyte Cells). The ED₅₀ for this effect is typically <12ng/mL.
Recombinant Human TRAIL Protein (rp152616)-SDS-PAGE 3μg/lane of Recombinant Human TRAIL was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 17.7 kDa.
Recombinant Human TRAIL Protein (rp152616) - Protein Bioactivity Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D (A113142). The ED₅₀ for this effect is 1.84 ng/mL.