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Recombinant Rat GM-CSF Protein

Recombinant Rat GM-CSF Protein

无动物源

≥98%(SDS-PAGE&HPLC)

功能和特点

表达系统: E. coli
Accession #: P48750
蛋白标签: No tag
生物活性: Measured in a cell proliferation assay using murine FDC-P1 cells. The ED50 for this effect is typically <0.02 ng/mL.
内毒素水平: <0.01 EU/μg

有货

库存信息

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库存信息

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库存信息

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货号 (SKU)	包装规格	是否现货
rp155067-10μg	10μg	现货
rp155067-50μg	50μg	现货
rp155067-1mg	1mg	期货

查看相关系列

点击查看蛋白信息: CSF2

Accession#:P48750 (1) CSF2 (14) Gene ID:116630 (1) GM-CSF (14)

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基本描述

产品名称	Recombinant Rat GM-CSF Protein
别名	重组大鼠粒巨噬细胞集落刺激因子 \| 重组大鼠 GM-CSF 蛋白
英文别名	Colony stimulating factor 2 (granulocyte-macrophage) \| Colony-stimulating factor \| CSF \| CSF2 \| CSF-2 \| GMCSF \| GM-CSF \| granulocyte-macrophage colony-stimulating factor \| granulocyte-macrophage colony stimulating factor \| MGC131935 \| MGC138897 \| Molgramo
规格或纯度	ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥98%(SDS-PAGE&HPLC)
产品介绍	GM-CSF是一种造血生长因子，刺激中性粒细胞和巨噬细胞的发育，促进早期红系巨核细胞和嗜酸性祖细胞的增殖和发育。它由内皮细胞、单核细胞、成纤维细胞和t淋巴细胞产生。GM-CSF抑制中性粒细胞迁移，增强成熟端细胞的功能活性。GM-CSF也被报道对非造血细胞有功能性作用，并可诱导人内皮细胞迁移和增殖。此外，它还能刺激多种肿瘤细胞系的增殖，包括成骨肉瘤、癌和腺癌细胞系。据报道，GM-CSF没有跨物种的生物学效应。重组鼠GM-CSF是一个14.5kDa的球状蛋白，由127个氨基酸残基组成。 Purity >98% SDS-PAGE. > 98 % by HPLC. Additional sequence information This product is for the mature full length protein. The signal peptide is not included. Function Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. Background GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages, and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. GM-CSF has also been reported to have a functional role on non-hematopoietic cells and can induce human endothelial cells to migrate and proliferate. Additionally, it can stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma and adenocarcinoma cell lines. It is reported that GM-CSF has no biological effects across species. Recombinant Rat GM-CSF is a 14.5kDa globular protein consisting of 127 amino acid residues.
生物活性	Measured in a cell proliferation assay using murine FDC-P1 cells. The ED50 for this effect is typically <0.02 ng/mL.
内毒素水平	<0.01 EU/μg
表达系统	E. coli
种属	大鼠(Rat)
氨基酸	18-144 aa
序列	APTRSPNPVTRPWKHVDAIKEALSLLNDMRALENEKNEDVDIISNEFSI QRPTCVQTRLKLYKQGLRGNLTKLNGALTMIASHYQTNCPPTPETDCE IEVTTFEDFIKNLKGFLFDIPFDCWKPVQK
纯度	＞98% (SDS-PAGE, HPLC)
蛋白标签	No tag
蛋白长度	Full length protein
无载体	Yes
无动物源	Yes
Accession #	P48750
来源	重组表达
预测分子量	14.5 kDa
SDS-PAGE	13.7 kDa, under reducing conditions; 13.7 kDa, under non-reducing conditions.

图片

Protein Bioactivity: Recombinant Rat GM-CSF Protein (rp155067)

Recombinant Rat GM-CSF Protein (rp155067)-Protein Bioactivity
Measured in a cell proliferation assay using FDC-P1 cells. The ED₅₀ for this effect is typically <0.01ng/mL.

SDS-PAGE: Recombinant Rat GM-CSF Protein (rp155067)

Recombinant Rat GM-CSF Protein (rp155067)-SDS-PAGE
3μg/lane of Recombinant Rat GM-CSF Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a single band at 13.7 kDa.

产品规格参数

物理形态	冻干(Lyophilized)
储存缓冲液	Lyophilized from a 0.2µm filtered solution in PBS, pH 7.4
复溶	1.This vial must be briefly centrifuged prior to opening to bring the contents to the bottom. 2. Reconstitute in a sterile aqueous buffer to an appropriate concentration. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	收货后建议分装，储存在 -20°C 温度下，避免冷冻/解冻循环。
分子类型	蛋白质

安全和危险性（GHS）

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找到4个结果

批号(Lot Number)	证书类型	日期	货号
ZJ25F0521943	分析证书	25-05-30	rp155067
ZJ25F0521942	分析证书	25-05-30	rp155067
ZJ23F0600298	分析证书	25-01-16	rp155067
ZJ23F0600299	分析证书	25-01-16	rp155067

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Recombinant Rat GM-CSF Protein

库存信息

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库存信息

基本描述

图片

产品规格参数

安全和危险性（GHS）

技术规格说明书

质检证书（CoA,COO,BSE/TSE 和分析图谱)

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