Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining. Envelope protein required for virus entry into host cell and for cell-cell fusion (syncytium formation). Description: Monkeypox is a zoonotic disease caused by monkeypox virus (MPXV), which is a member of orthopoxvirus genus. A30L protein is required for the association of electron-dense, granular, proteinaceous material with the concave surfaces of crescent membranes, an early step in viral morphogenesis. The A30L protein is believed to be located in the matrix between the core and membrane. In vivo and in vitro experiments provided evidence for the direct interaction of the A30L and G7L proteins and demonstrated that the stability of each one was dependent on its association with the other. A presumption was that the A30L protein is a key element in the linkage between the viral core and the membrane. And some data indicate that protein-protein interactions are needed for the association of the dense viroplasm with IV membranes. Of the two interacting proteins identified, the G7L protein appears to be a component of the core whereas the A30L protein may be a component of the matrix between the core and membrane.
规格
产品名称
Recombinant MPXV A30L Protein
别名
重组猴痘病毒 A30L 蛋白
英文别名
Envelope protein OPG155 | Protein A30 | OPG155 | A30L | IMV surface protein A30L | Monkeypox virus A30L | Monkeypox virus
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存条件
-80℃储存,避免反复冻融
运输条件
特低温运输
稳定性与储存
在 -20°C 下可保存 1 年,在 2-8°C 下可保存 1 个月。避免冷冻/解冻循环。
图片
Recombinant MPXV A30L Protein (rp155933) - SDS-PAGE 3 μg/lane of Recombinant MPVX A30L Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining. Showing a band at 25-30 kDa under reducing conditions and 23-28 kDa under non-reducing conditions.