The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake.
规格
产品名称
Recombinant Human LR3 IGF-1 Protein
别名
重组人 LR3 IGF-1 蛋白
英文别名
IBP1 | IGF I | IGF IA | IGF IB | IGF-I | Igf1 | IGF1_HUMAN | IGF1A | IGFI | IGFIA | Insulin like growth factor 1 | Insulin like growth factor 1 (somatomedin C) | Insulin like growth factor IA | Insulin like growth factor IB | Insulin-like growth factor I
10.1 kDa, under reducing conditions; 10.1 kDa, under non-reducing conditions.
CAS编号和信息
946870-92-4
分子类型
蛋白质
产品线
biological_products
储存与运输
应用
Active, SDS-PAGE
物理形态
冻干(Lyophilized)
储存缓冲液
10mM PBS, pH 7.0
复溶
Reconstitute in water to a concentration of 1mg/ml.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
Freeze-dried powder can be stored at room temperature for 3 weeks, or frozen at -20℃ for long-term storage. After redissolving it can be refrigerated at 4℃ for at least 2-7 days.
图片
Recombinant Human LR3 IGF-1 Protein (rp155967) - Protein Bioactivity Measured in a serum-free cell proliferation assay using MCF‑7 human breast cancer cells. The ED₅₀ for this effect is typically less than 10 ng/mL.
Recombinant Human LR3 IGF-1 Protein (rp155967) - SDS-PAGE 4μg/lane of Recombinant Human LR3 IGF-1 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a single band at 10.1 kDa.