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Recombinant Human FOXP3 Protein

Recombinant Human FOXP3 Protein

Name: Recombinant Human FOXP3 Protein
SKU: rp156651
Availability: InStock

货号: rp156651

COA

有货

级别和纯度: 无载体 ? 无叠氮钠 ? His标签 ? ≥90%(SDS-PAGE)

Accession #

Q9BZS1

蛋白标签

N-His

表达系统

E. coli

生物活性

Testing in progress

规格

库存

价格

数量

10μg

rp156651-10μg

现货

¥799.90

50μg

rp156651-50μg

现货

¥1,999.90

100μg

rp156651-100μg

现货

¥3,399.90

1mg

rp156651-1mg

期货

¥21,999.90

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概述规格储存与运输图片高级数据质检证书(CoA,COO,BSE/TSE 和分析图谱) 技术文档和文章溶液计算器

概述

Purity:>90%, by SDS-PAGE visualized with Coomassie® Blue Staining.

Description：

FOXP3 is a transcriptional regulator which is crucial for the development and inhibitory function of regulatory T-cells (Treg). It plays an essential role in maintaining homeostasis of the immune system by allowing the acquisition of full suppressive function and stability of the Treg lineage, and by directly modulating the expansion and function of conventional T-cells. Can act either as a transcriptional repressor or a transcriptional activator depending on its interactions with other transcription factors, histone acetylases and deacetylases. The suppressive activity of Treg involves the coordinate activation of many genes, including CTLA4 and TNFRSF18 by FOXP3 along with repression of genes encoding cytokines such as interleukin-2 (IL2) and interferon-gamma (IFNG). Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome.

规格

产品名称

Recombinant Human FOXP3 Protein

别名

Scurfin,重组人FOXP3蛋白 | 重组人 FOXP3 蛋白

英文别名

Forkhead box protein P3 | Scurfin

规格或纯度

无载体,无叠氮钠,His标签,≥90%(SDS-PAGE)

生物活性

Testing in progress

表达系统

E. coli

种属

人(Human)

氨基酸

1-431 aa

序列

MGHHHHHHMPNPRPGKPSAPSLALGPSPGASPSWRAAPKASDLLGARGPGGTFQGRDLRGGAHASSSSLNPMPPSQLQLPTLPLVMVAPSGARLGPLPHLQALLQDRPHFMHQLSTVDAHARTPVLQVHPLESPAMISLTPPTTATGVFSLKARPGLPPGINVASLEWVSREPALLCTFPNPSAPRKDSTLSAVPQSSYPLLANGVCKWPGCEKVFEEPEDFLKHCQADHLLDEKGRAQCLLQREMVQSLEQQLVLEKEKLSAMQAHLAGKMALTKASSVASSDKGSCCIVAAGSQGPVVPAWSGPREAPDSLFAVRRHLWGSHGNSTFPEFLHNMDYFKFHNMRPPFTYATLIRWAILEAPEKQRTLNEIYHWFTRMFAFFRNHPATWKNAIRHNLSLHKCFVRVESEKGAVWTVDELEFRKKRSQRPSRCSNPTPGP

蛋白标签

N-His

无载体

Yes

无动物源

来源

重组表达

预测分子量

48.2 kDa

SDS-PAGE

48.0 kDa, reducing conditions

分子类型

蛋白质

产品线

生物产品

储存与运输

物理形态

冻干(Lyophilized)

储存缓冲液

Lyophilized from PBS，2 MUrea，pH7.4

复溶

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.5 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.

储存条件

-20°C储存,避免反复冻融

运输条件

超低温运输

稳定性与储存

在 -20°C 下可保存 1 年。避免冷冻/解冻循环。

图片

SDS-PAGE: Recombinant Human FOXP3 protein (rp156651)

Recombinant Human FOXP3 protein (rp156651) - SDS-PAGE
Recombinant Human FOXP3 protein was resolved with SDS-PAGE under reducing (R) conditions and visualized by Coomassie® Blue staining, showing a band at 48.0 kDa.