Purity: >90%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description: Major histocompatibility complex, class II, DR alpha (HLA-DRA) belongs to the MHC class II family. HLA-DRA binds peptides derived from antigens which access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for identification by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mainly by degradation of proteins which access the endocytic route, where they are processed by lysosomal proteases and other hydrolases.
规格
产品名称
Recombinant Human HLA-DRA Protein
别名
重组人HLA-DRA蛋白. | 重组人HLA-DRA蛋白. | 重组人类 HLA-DRA 蛋白
英文别名
Major Histocompatibility Complex | Class II | DR Alpha | HLA-DRA1 | MHC Class II AntigenDRA | MLRW | Histocompatibility Antigen HLA-DR Alpha | HLAClass II Histocompatibility Antigen | DR Alpha Chain | MHC Cell Surface Glycoprotein | HLA-DRA | MHC class II
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.5 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20°C 下可稳定保存 1 年。避免冷冻/解冻循环。
图片
Recombinant Human HLA-DRA Protein (rp170117) - SDS-PAGE 3 μg/lane of Recombinant Human HLA-DRA Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 26.4 kDa.