Cyclophilin A, also called Peptidyl-prolyl Isomerase A, PPIA, CYPA, and CYPH, was originally characterized for its ability to catalyze the transition between cis- and trans-proline residues critical for proper folding of proteins. Cyclophilin is also incorporated into many viruses, including HIV-1, where it has been speculated to be involved in functions such as viral assembly and infectivity. The immunosuppressive activity of cyclosporins has been correlated with their ability to form complexes with cyclophilins that inhibit calcineurin phosphatase activity and prevent incorporation of cyclophilin into viral particles. The cyclosporin/cyclophilin complex selectively binds and inactivates calcineurin, making it a useful inhibitor for studying calcineurin activity.
规格
产品名称
Recombinant Human Cyclophilin A Protein
别名
重组人Cyclophilin A蛋白 | 重组人类环丝氨酸蛋白酶A
英文别名
Cyclosporin A-binding protein | CYPA | CYPAMGC12404 | CYPH | EC 5.2.1.8 | MGC117158 | MGC23397 | peptidyl-prolyl cis-trans isomerase A | Cyclophilin A | peptidylprolyl isomerase A (cyclophilin A) | PPIA | PPIase A | Rotamase A | Rotamase | T cell cyclophi
Recombinant Human Cyclophilin A Protein (rp189612) - SDS-PAGE 3 μg/lane of Recombinant Human Cyclophilin A Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 18.5 kDa.
ZJ24F0708545
危险品化学品经营许可证（带存储）