Immobilized Recombinant Human Cyclophilin A Protein (rp183694) at 1.0 μg/mL can bind Recombinant Cyclophilin A Antibody (Ab098509) with the EC50 of 7.2 ng/mL.
Purity: >95%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description： Cyclophilin A, also called Peptidyl-prolyl Isomerase A, PPIA, CYPA, and CYPH, was originally characterized for its ability to catalyze the transition between cis- and trans-proline residues critical for proper folding of proteins. Cyclophilin is also incorporated into many viruses, including HIV-1, where it has been speculated to be involved in functions such as viral assembly and infectivity. The immunosuppressive activity of cyclosporins has been correlated with their ability to form complexes with cyclophilins that inhibit calcineurin phosphatase activity and prevent incorporation of cyclophilin into viral particles. The cyclosporin/cyclophilin complex selectively binds and inactivates calcineurin, making it a useful inhibitor for studying calcineurin activity.
规格
产品名称
Recombinant Human Cyclophilin A Protein
别名
重组人Cyclophilin A蛋白 | 重组人类环丝氨酸蛋白酶A
英文别名
Cyclophilin A | Cyclosporin A-binding protein | CYPA | CYPAMGC12404 | CYPH | EC 5.2.1.8 | MGC117158 | MGC23397 | peptidyl-prolyl cis-trans isomerase A | peptidylprolyl isomerase A (cyclophilin A) | PPIA | PPIase A | Rotamase A | Rotamase | T cell cyclophi
规格或纯度
无载体,生物活性,ActiBioPure™,His标签,SUMO标签,≥95%(SDS-PAGE)
生物活性
Immobilized Recombinant Human Cyclophilin A Protein (rp183694) at 1.0 μg/mL can bind Recombinant Cyclophilin A Antibody (Ab098509) with the EC50 of 7.2 ng/mL.
32.6 kDa, under reducing conditions; 32.6 kDa, under non-reducing conditions
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
液体
储存缓冲液
PBS, 10% Glycerol, pH 7.4
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
-20℃ 存储12个月；收货后建议分装，避免反复冻融。
图片
Recombinant Human Cyclophilin A Protein (rp183694) - SDS-PAGE 3 μg/lane of Recombinant Human Cyclophilin A Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 32.6 kDa.
Recombinant Human Cyclophilin A Protein (rp183694) - ELISA
Immobilized Recombinant Human Cyclophilin A Protein (rp183694) at 1.0 μg/mL can bind Recombinant Cyclophilin A Antibody (Ab098509) with the EC50 of 7.2 ng/mL.
ZJ26F0535112
危险品化学品经营许可证（带存储）