计算溶液所需的质量、体积或浓度。
Protein Bioactivity: Recombinant Rat IL-1 beta/IL-1F2 Protein (rp192260)
Fully biologically active determined by the dose dependent increase in proliferation of TF-1 cells. ED₅₀ for this effect is 39.0 ng/mL.
货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
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rp192260-10μg |
10μg |
期货 ![]() |
| |
rp192260-50μg |
50μg |
期货 ![]() |
| |
rp192260-100μg |
100μg |
期货 ![]() |
| |
rp192260-1mg |
1mg |
期货 ![]() |
|
产品名称 | Recombinant Rat IL-1 beta/IL-1F2 Protein |
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别名 | 重组人Rat IL-1 beta/IL-1F2蛋白 | 重组大鼠白细胞介素-1β蛋白 |
英文别名 | catabolin | IL1 beta | IL-1 beta | IL-1 | IL1B | IL-1b | IL1-BETA | IL-1F2 | IL1F2IL-1 beta | interleukin 1, beta | interleukin-1 beta | preinterleukin 1 beta | pro-interleukin-1-beta |
规格或纯度 | 无载体, 生物活性, ActiBioPure™, 高性能, ≥95%(SDS-PAGE), 见COA |
生化机理 | Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair in the cortex. The IL1 superfamily consists of three members, IL1A (IL1 alpha), IL1B (IL1 beta), and IL1 receptor antagonist (IL1Ra). In clinical, it has been reported that Interleukin (IL)-1 may influence Th1 / Th2 immune responsiveness and has been implicated in the establishment of a successful pregnancy. Proinflammatory interleukin (IL)-1 gene polymorphisms associated with high levels of IL-1beta activity increase the risk for hypochlorhydria and distal gastric carcinoma. IL1B polymorphisms may be involved in susceptibility to SSc. Moreover, the IL2-384-G allele may be a marker for the limited phenotype of systemic sclerosis (SSc). |
生物活性 | Fully biologically active determined by the dose dependent increase in proliferation of TF-1 cells. ED50 for this effect is 39.0 ng/mL. |
内毒素水平 | <1.0 EU/μg |
表达系统 | E. coli |
种属 | 大鼠(Rat) |
氨基酸 | 117 -268 aa |
序列 | MGSSHHHHHHSSGLVPRGSHMASMSDSEVNQEAKPEVKPEVKPETHINLKVSDGSSEIFFKIKKTTPLRRLMEAFAKRQGKEMDSLRFLYDGIRIQADQTPEDLDMEDNDIIEAHREQIGGVPIRQLHCRLRDEQQKCLVLSDPCELKALHLNGQNISQQVVFSMSFVQGETSNDKIPVALGLKGLNLYLSCVMKDGTPTLQLESVDPKQYPKKKMEKRFVFNKIEVKTKVEFESAQFPNWYISTSQAEHRPVFLGNSNGRDIVDFTMEPVSS |
蛋白标签 | N-His & SUMO |
无载体 | Yes |
无动物源 | No |
Accession # | Q63264 |
来源 | 重组表达 |
预测分子量 | 30.9 kDa |
SDS-PAGE | 32.7 kDa, under reducing conditions; 32.7 kDa, under non-reducing conditions. |
Protein Bioactivity: Recombinant Rat IL-1 beta/IL-1F2 Protein (rp192260)
Fully biologically active determined by the dose dependent increase in proliferation of TF-1 cells. ED₅₀ for this effect is 39.0 ng/mL.
Recombinant Rat IL-1 beta/IL-1F2 Protein (rp192260) - SDS-PAGE
3 μg/lane of Recombinant Rat IL-1 beta/IL-1F2 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 32.7 kDa under reducing conditions and 32.7 kDa under non-reducing conditions.
物理形态 | 液体 |
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储存缓冲液 | PBS, 10% Glycerol, pH 7.4 |
浓度 | 见COA |
储存温度 | -20°C储存,避免反复冻融 |
运输条件 | 超低温冰袋运输 |
稳定性与储存 | -20℃存储 6个月;收货后建议分装,避免反复冻融。 |
分子类型 | 蛋白质 |