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Recombinant Human PLSCR1 Protein

Recombinant Human PLSCR1 Protein

Name: Recombinant Human PLSCR1 Protein
SKU: rp329377
Availability: InStock

货号: rp329377

COA

有货

级别和纯度: 无动物源 ? 无载体 ? His标签 ? ≥80%(SDS-PAGE) 蛋白浓度：见COA

Accession #

O15162

蛋白标签

N-His

表达系统

E. coli

规格

库存

价格

数量

10μg

rp329377-10μg

现货

¥699.90

50μg

rp329377-50μg

现货

¥1,999.90

100μg

rp329377-100μg

现货

¥2,999.90

1mg

rp329377-1mg

期货

¥15,999.90

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规格储存与运输技术文档高级数据质检证书（CoA,COO,BSE/TSE 和分析图谱) 技术文档和文章溶液计算器

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为什么选择此级别

His标签,无动物源,无载体级提供 ≥80%(SDS-PAGE) 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。

🌡

储存与运输

-80℃储存,避免反复冻融。特低温运输。请查阅批次 COA 获取详细规格。

📋

质量文档

SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。

📚

文献证明

在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。

规格

产品名称

Recombinant Human PLSCR1 Protein

别名

磷脂紊乱蛋白 1 | 磷脂转位酶 1 | 钙依赖磷脂翻转蛋白 1

英文别名

PLSCR1 | Scramblase 1 | TRA1 | NOR1 | Tras1

规格或纯度

无动物源, 无载体, His标签, ≥80%(SDS-PAGE), 蛋白浓度：见COA

生化机理

Catalyzes calcium-induced ATP-independent rapid bidirectional and non-specific movement of phospholipids (lipid scrambling or lipid flip-flop) between the inner and outer leaflet of the plasma membrane resulting in collapse of the phospholipid asymmetry which leads to phosphatidylserine externalization on the cell surface.Mediates calcium-dependent phosphatidylserine externalization and apoptosis in neurons via its association with TRPC5.Also exhibits magnesium-dependent nuclease activity against double-stranded DNA and RNA but not single-stranded DNA and can enhance DNA decatenation mediated by TOP2A.Negatively regulates FcR-mediated phagocytosis in differentiated macrophages. May contribute to cytokine-regulated cell proliferation and differentiation.May play a role in the antiviral response of interferon (IFN) by amplifying and enhancing the IFN response through increased expression of select subset of potent antiviral genes.Inhibits the functions of viral transactivators, including human T-cell leukemia virus (HTLV)-1 protein Tax, human immunodeficiency virus (HIV)-1 Tat, human hepatitis B virus (HBV) HBx, Epstein-Barr virus (EBV) BZLF1 and human cytomegalovirus IE1 and IE2 proteins through direct interactions. Also mediates the inhibition of influenza virus infection by preventing nuclear import of the viral nucleoprotein/NP.Plays a crucial role as a defense factor against SARS-CoV-2 independently of its scramblase activity by directly targeting nascent viral vesicles to prevent virus-membrane fusion and the release of viral RNA into the host-cell cytosol.(Microbial infection) Acts as an attachment receptor for HCV. Post-translational: Phosphorylation at Thr-161 by PKC/PKCD increases its phospholipid scramblase activity during both cell stimulation and apoptosis.Phosphorylated by OXSR1 in the presence of RELT.Palmitoylation is required for its phospholipid scramblase activity.Palmitoylation regulates its localization to the cell membrane or the nucleus; trafficking to the cell membrane is dependent upon palmitoylation whereas in the absence of palmitoylation, localizes to the nucleus.

表达系统

E. coli

种属

人(Human)

氨基酸

1-318 aa

序列

MHHHHHHDKQNSQMNASHPETNLPVGYPPQYPPTAFQGPPGYSGYPGPQVSYPPPPAGHSGPGPAGFPVPNQPVYNQPVYNQPVGAAGVPWMPAPQPPLNCPPGLEYLSQIDQILIHQQIELLEVLTGFETNNKYEIKNSFGQRVYFAAEDTDCCTRNCCGPSRPFTLRIIDNMGQEVITLERPLRCSSCCCPCCLQEIEIQAPPGVPIGYVIQTWHPCLPKFTIQNEKREDVLKISGPCVVCSCCGDVDFEIKSLDEQCVVGKISKHWTGILREAFTDADNFGIQFPLDLDVKMKAVMIGACFLIDFMFFESTGSQEQKSGVW

蛋白标签

N-His

无载体

Yes

无动物源

Yes

预测分子量

35.9 kDa

SDS-PAGE

39 kDa, under reducing conditions.

分子类型

蛋白质

产品线

生物产品

储存与运输

物理形态

液体

储存缓冲液

20mM Tris-HCl, 200mM NaCl, 1mM DTT, 30% Glycerol, pH=7.0

浓度

蛋白浓度：见COA

储存条件

-80℃储存,避免反复冻融

运输条件

特低温运输

稳定性与储存

长期储存-80℃（12个月）；收货后建议分装，避免反复冻融。

技术文档

📋 安全数据表 (SDS)

全面的危险、操作、储存及法规合规文件。

下载 SDS →

✅ 分析证书 (COA)

批次质量数据。输入批号以获取对应 COA。

查询 COA →

📊 产品数据表

产品规格和应用的快速参考摘要。

查看数据表 →

🔬 规格说明书

该级别的完整质量属性和验收标准。

查看规格说明 →

高级数据

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到3个结果

批号(Lot Number)	证书类型	货号
ZJ26F0939497	分析证书	rp329377
ZJ26F0939496	分析证书	rp329377
ZJ26F0939498	分析证书	rp329377

技术文档和文章

PLSCR家族在细胞死亡、凝血与炎症信号研究中的应用

目录：技术文章

探索主题:

细胞凋亡磷脂酰丝氨酸细胞死亡凝血炎症信号 PLSCR家族 PLSCR1 phospholipid scramblase 磷脂爬行酶 PS外翻血小板活化干扰素响应

Applications of the PLSCR Family in Cell Death, Coagulation, and Inflammatory Signaling Research

目录：技术文章

探索主题:

Apoptosis Phosphatidylserine Coagulation inflammatory signaling cell death PLSCR1 phospholipid scramblase PLSCR family PS externalization platelet activation interferon response

溶液计算器