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Ivosidenib (AG-120)CAS号 : 1448347-49-6(DMSO)分子式: C28H22ClF3N6O3 分子量: 582.96SMILES: FC1=CN=CC(=C1)N(C(C(=O)NC2CC(F)(F)C2)C3=C(Cl)C=CC=C3)C(=O)C4CCC(=O)N4C5=NC=CC(=C5)C#N
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BMS202（PD-1 / PD-L1抑制剂2）CAS号 : 1675203-84-5(DMSO)分子式: C25H29N3O3 分子量: 419.52SMILES: COC1=C(CNCCNC(C)=O)C=CC(=N1)OCC2=C(C)C(=CC=C2)C3=CC=CC=C3
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AG-120(外消旋)CAS号 : 1448346-63-1分子式: C28H22ClF3N6O3 分子量: 582.96IUPAC Name: (2S)-N-[1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl]-1-(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamideSMILES: C1CC(=O)N(C1C(=O)N(C2=CC(=CN=C2)F)C(C3=CC=CC=C3Cl)C(=O)NC4CC(C4)(F)F)C5=NC=CC(=C5)C#NInChIKey: WIJZXSAJMHAVGX-XADRRFQNSA-NInChI: InChI=1S/C28H22ClF3N6O3/c29-21-4-2-1-3-20(21)25(26(40)36-18-11-28(31,32)12-18)37(19-10-17(30)14-34-15-19)27(41)22-5-6-24(39)38(22)23-9-16(13-33)7-8-35-23/h1-4,7-10,14-15,18,22,25H,5-6,11-12H2,(H,36,40)/t22-,25?/m0/s1
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BMS-1001CAS号 : 2113650-03-4分子式: C35H34N2O7 分子量: 594.65IUPAC Name: (2R)-2-[[2-[(3-cyanophenyl)methoxy]-4-[[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]methoxy]-5-methylphenyl]methylamino]-3-hydroxypropanoic acidSMILES: CC1=CC(=C(C=C1OCC2=C(C(=CC=C2)C3=CC4=C(C=C3)OCCO4)C)OCC5=CC(=CC=C5)C#N)CNC(CO)C(=O)OInChIKey: UWNXGZKSIKQKAH-SSEXGKCCSA-NInChI: InChI=1S/C35H34N2O7/c1-22-13-28(18-37-30(19-38)35(39)40)33(43-20-25-6-3-5-24(14-25)17-36)16-32(22)44-21-27-7-4-8-29(23(27)2)26-9-10-31-34(15-26)42-12-11-41-31/h3-10,13-16,30,37-38H,11-12,18-21H2,1-2H3,(H,39,40)/t30-/m1/s1
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奥塔西德尼(FT-2102)CAS号 : 1887014-12-1分子式: C18H15ClN4O2 分子量: 354.79IUPAC Name: 5-[[(1S)-1-(6-chloro-2-oxo-1H-quinolin-3-yl)ethyl]amino]-1-methyl-6-oxopyridine-2-carbonitrileSMILES: CC(C1=CC2=C(C=CC(=C2)Cl)NC1=O)NC3=CC=C(N(C3=O)C)C#NInChIKey: NEQYWYXGTJDAKR-JTQLQIEISA-NInChI: InChI=1S/C18H15ClN4O2/c1-10(21-16-6-4-13(9-20)23(2)18(16)25)14-8-11-7-12(19)3-5-15(11)22-17(14)24/h3-8,10,21H,1-2H3,(H,22,24)/t10-/m0/s1
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Vorasidenib (AG-881)CAS号 : 1644545-52-7 Compound CID : 117817422分子式: C14H13ClF6N6 分子量: 414.74IUPAC Name: 6-(6-chloropyridin-2-yl)-2-N,4-N-bis[(2R)-1,1,1-trifluoropropan-2-yl]-1,3,5-triazine-2,4-diamineSMILES: CC(C(F)(F)F)NC1=NC(=NC(=N1)C2=NC(=CC=C2)Cl)NC(C)C(F)(F)FInChIKey: QCZAWDGAVJMPTA-RNFRBKRXSA-NInChI: InChI=1S/C14H13ClF6N6/c1-6(13(16,17)18)22-11-25-10(8-4-3-5-9(15)24-8)26-12(27-11)23-7(2)14(19,20)21/h3-7H,1-2H3,(H2,22,23,25,26,27)/t6-,7-/m1/s1
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Envafolimab (anti-PD-L1)关联靶标: CD274
- 简短描述: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; VHH; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- 种属反应性: 人(Human), 食蟹猴(Cynomolgus monkey)
- 亚型: VHH
- 宿主种属: 人(Human)
- 偶联: Unconjugated
CAS号 : 2102192-68-5 -
Sugemalimab (anti-PD-L1)关联靶标: CD274
- 简短描述: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- 种属反应性: 人(Human)
- 亚型: Human IgG4SP
- 宿主种属: 人(Human)
- 偶联: Unconjugated
CAS号 : 2256084-03-2 -
Lesabelimab (anti-PD-L1)关联靶标: CD274
- 种属反应性: 人(Human)
- 亚型: Human IgG1
- 宿主种属: 人(Human)
- 偶联: Unconjugated
CAS号 : 2475402-56-1
