盐酸硫胺

CAS: 67-03-8 货号: T656958 分子式: C₁₂H₁₈Cl₂N₄OS 分子量: 337.27 Beilstein号: 3851771 EC号: 200-641-8 PubChem CID: 6202

24篇引用文献 COA

有货

级别和纯度: 无动物源 ? 低内毒素 ? 用于细胞培养 ? ≥99%

别名

维生素B1,盐酸硫胺素,尼克酸|硫胺盐酸盐|维生素B1 盐酸盐, 硫胺素盐酸盐|维生素B1盐酸盐|硫胺素盐酸盐

储存条件

室温,充氩

运输条件

常规运输

规格

库存

价格

数量

T656958-5g

现货

¥182.90

25g

T656958-25g

现货

¥439.90

100g

T656958-100g

现货

¥1,162.90

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概述规格名称和识别符技术文档高级数据系统学分类三维结构关联靶点（人）关联靶点（其它种属）作用机制质检证书（CoA,COO,BSE/TSE 和分析图谱) 化学和物理性质安全和危险性（GHS）此产品的引用文献技术文档和文章引用文献溶液计算器

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为什么选择此级别

低内毒素,无动物源,用于细胞培养级提供 ≥99% 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。

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储存与运输

室温,充氩。常规运输。请查阅批次 COA 获取详细规格。

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质量文档

SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。

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文献证明

在色谱分析、有机合成和交叉偶联反应领域已被 24 篇同行评审文献引用。

概述

微有噻唑气味。味苦。对光敏感。暴露于空气中易吸湿，干燥品在空气中迅速吸收4%的水分。溶解度:1 g/mL水，1 g/18 mL甘油， 1 g/100 mL 95% 乙醇，1 g/315 mL 无水乙醇，溶于丙二醇，实际上不溶于醚、苯、己烷和氯仿。

规格

别名

维生素B1,盐酸硫胺素,尼克酸 | 硫胺盐酸盐 | 维生素B1 盐酸盐, 硫胺素盐酸盐 | 维生素B1盐酸盐 | 硫胺素盐酸盐

规格或纯度

无动物源, Low Endotoxin, 用于细胞培养, ≥99%

英文名称

Thiamine hydrochloride

储存条件

室温,充氩

运输条件

常规运输

纯度

≥99%

名称和识别符

EC号

200-641-8

分子类型

小分子

IUPAC Name

2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol;chloride;hydrochloride

INCHI

1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1

InChi Key

DPJRMOMPQZCRJU-UHFFFAOYSA-M

Smiles

CC1=NC(N)=C(C[N+]2=CSC(CCO)=C2C)C=N1.Cl.[Cl-]

Isomeric SMILES

CC1=C(SC=[N+]1CC2=CN=C(N=C2N)C)CCO.Cl.[Cl-]

关联CAS

59-43-8

PubChem CID

6202

分子量

337.27

Beilstein号

3851771

Reaxy-Rn

3851771

技术文档

📋 安全数据表 (SDS)

全面的危险、操作、储存及法规合规文件。

下载 SDS →

✅ 分析证书 (COA)

批次质量数据。输入批号以获取对应 COA。

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📊 产品数据表

产品规格和应用的快速参考摘要。

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🔬 规格说明书

该级别的完整质量属性和验收标准。

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高级数据

系统学分类

分类树（Taxonomy Tree）

界（kingdom) 有机化合物
- 超类（Superclass) 有机杂环化合物
  - 类（Class) 二嗪类
    - 亚类（Subclass）嘧啶和嘧啶衍生物

界（kingdom)	有机化合物
超类（Superclass)	有机杂环化合物
类（Class)	二嗪类
亚类（Subclass）	嘧啶和嘧啶衍生物
中间层级节点（Intermediate Tree Nodes）	暂无
直接上位类(Direct Parent)	硫胺素
其他上位类（Alternative Parents）	氨基嘧啶及其衍生物 4,5-二取代噻唑咪唑内酰胺类杂芳族化合物氮杂环化合物伯胺伯醇有机光子化合物有机氯化物盐盐酸盐碳氢化合物衍生物
分子骨架（Molecular Framework)	芳香族杂单环化合物
取代基（Substituents）	4,5-二取代-1,3-噻唑 - 羟基苯甲酸酯 - 氨基酸 - 氨基吡啶 - 芳香族杂单环化合物 - 氮杂环 - 吡唑 - 杂芳香族化合物 - 烃衍生物 - 氟氯烃 - 咪唑内酰胺 - 有机氯酸盐 - 有机硝基化合物 - 有机氧化合物 - 有机盐 - 有机氮化合物 - 有机氧化合物 - 有机氮化合物 - 初级醇 - 初级胺 - 硫脲嗪 - 噻唑
描述（Description）	该化合物属于有机化合物中的硫胺素类。这类化合物含有硫胺素结构单元，其特征为3-[(4-氨基-2-甲基-嘧啶-5-基)甲基]-4-甲基-噻唑-5-基主链。
外部描述符（External Descriptors）	thiamine

三维结构

交互式化学结构模型

球棍
棍棒
线框模型
空间填充
显示氢气
动画

关联靶点（人）

CYP2D6 Tclin Cytochrome P450 2D6 (33882 活性数据)

点击查看靶蛋白信息： CYP2D6

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

CYP1A2 Tchem Cytochrome P450 1A2 (26471 活性数据)

点击查看靶蛋白信息： CYP1A2

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

CYP2C9 Tchem Cytochrome P450 2C9 (32119 活性数据)

点击查看靶蛋白信息： CYP2C9

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

CYP2C19 Tchem Cytochrome P450 2C19 (29246 活性数据)

点击查看靶蛋白信息： CYP2C19

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

CYP3A4 Tclin Cytochrome P450 3A4 (53859 活性数据)

点击查看靶蛋白信息： CYP3A4

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

GMNN Tbio Geminin (128009 活性数据)

点击查看靶蛋白信息： GMNN

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

PMP22 Tbio Peripheral myelin protein 22 (699 活性数据)

点击查看靶蛋白信息： PMP22

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 (22556 活性数据)

点击查看靶蛋白信息： USP1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

TARDBP Tchem TAR DNA-binding protein 43 (40113 活性数据)

点击查看靶蛋白信息： TARDBP

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

关联靶点（其它种属）

ampC Beta-lactamase AmpC (62480 活性数据)

点击查看靶蛋白信息： ampC

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

GCN5 Histone acetyltransferase GCN5 (89 活性数据)

点击查看靶蛋白信息： GCN5

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 活性数据)

点击查看靶蛋白信息： rep

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

TGR Thioredoxin glutathione reductase (28579 活性数据)

点击查看靶蛋白信息： TGR

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

vpr Aberrant vpr protein (14595 活性数据)

点击查看靶蛋白信息： vpr

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 活性数据)

点击查看此靶标相关信息

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

化学和物理性质

溶解性

Soluble in water, glycerol, ethanol, dimethyl sulfoxide and methanol. Insoluble in benzene, hexane, chloroform and ether.

密度

1.401

敏感性

对光和湿度敏感

熔点

250°C

分子量

337.300 g/mol

XLogP3

氢键供体数Hydrogen Bond Donor Count

氢键受体数Hydrogen Bond Acceptor Count

可旋转键计数Rotatable Bond Count

精确质量Exact Mass

336.058 Da

单同位素质量Monoisotopic Mass

336.058 Da

拓扑极表面积Topological Polar Surface Area

104.000 Å²

重原子数Heavy Atom Count

形式电荷Formal Charge

复杂度Complexity

268.000

同位素原子数Isotope Atom Count

定义的原子立体中心计数Defined Atom Stereocenter Count

未定义的原子立体中心计数Undefined Atom Stereocenter Count

定义的键立体中心计数Defined Bond Stereocenter Count

未定义的键立体中心计数Undefined Bond Stereocenter Count

所有立体化学键的总数The total count of all stereochemical bonds

共价键合单元计数Covalently-Bonded Unit Count

安全和危险性（GHS）

象形图

GHS07

信号词

警告

危险声明

H315: 引起皮肤刺激

H319: 引起严重眼睛刺激

H335: 可能引起呼吸道刺激

预防措施声明

P264: 处理后要彻底洗手。

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。

P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

P337+P313: 如仍觉眼刺激：求医/就诊。

WGK Germany

RTECS

XI7350000

Merck Index

9295

个人防护装备

Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到21个结果

批号(Lot Number)	证书类型	货号
I2604284	分析证书	T656958
I2604282	分析证书	T656958
H2605552	分析证书	T656958
H2605550	分析证书	T656958
H2605549	分析证书	T656958
H2605548	分析证书	T656958
G2616435	分析证书	T656958
G2616434	分析证书	T656958
G2616433	分析证书	T656958
A2613695	分析证书	T656958
A2613696	分析证书	T656958
A2613697	分析证书	T656958
D2527498	分析证书	T656958
D2527499	分析证书	T656958
D2527008	分析证书	T656958
A2514529	分析证书	T656958
A2514543	分析证书	T656958
A2514542	分析证书	T656958
D2409301	分析证书	T656958
D2409300	分析证书	T656958
D2409298	分析证书	T656958

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技术文档和文章

用于细胞培养

目录：阿拉丁试剂的规格、级别和纯度

探索主题:

用于细胞培养

For Cell Culture

目录：阿拉丁试剂的规格、级别和纯度

探索主题:

For Cell Culture

噻唑（Thiazole）全景解析：结构特色、应用价值、选型要点与产品导航（表1–表4）

目录：技术文章

探索主题:

杂环化学噻唑唑类

A Comprehensive Overview of Thiazole: Structural Features, Application Value, Selection Considerations, and Product Navigation (Tables 1–4)

目录：技术文章

探索主题:

heterocyclic chemistry Thiazole azole

为什么小分子也能当催化剂：从反应目标、可活化结构位点到有机催化体系判断

目录：技术文章

探索主题:

有机催化剂

Why Small Molecules Can Also Serve as Catalysts: Judging Organocatalytic Systems from Reaction Objectives and Activatable Structural Sites

目录：技术文章

探索主题:

Organocatalyst

此产品的引用文献

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引用文献

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3. Yanshen Nie, Li Yu, Lianlian Mao, Wenxuan Zou, Xiufeng Zhang, Jie Zhao. (2022) Vitamin B1 THIAMIN REQUIRING1 synthase mediates the maintenance of chloroplast function by regulating sugar and fatty acid metabolism in rice. Journal of Integrative Plant Biology, 64 (8): (1575-1595). [PMID:35603832] [10.1111/jipb.13283]
4. Yi Ma, Mawda Elmhadi, Chao Wang, Hao Zhang, Hongrong Wang. (2021) Dietary supplementation of thiamine down-regulates the expression of mitophagy and endoplasmic reticulum stress-related genes in the rumen epithelium of goats during high-concentrate diet feeding. Italian Journal of Animal Science, [10.1080/1828051X.2021.1985944]
5. Naymul Karim, Mohammad Rezaul Islam Shishir, Tao Bao, Wei Chen. (2021) Effect of cold plasma pretreated hot-air drying on the physicochemical characteristics, nutritional values and antioxidant activity of shiitake mushroom. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 101 (15): (6271-6280). [PMID:33949697] [10.1002/jsfa.11296]
6. Linyu Wang, Yi Xie, Yuxi Yang, Huihui Liang, Li Wang, Yonghai Song. (2020) Electroactive Covalent Organic Frameworks/Carbon Nanotubes Composites for Electrochemical Sensing. ACS Applied Nano Materials, [10.1021/acsanm.9b02257]
7. Pengjuan Ni, Dafeng Jiang, Chuanxia Chen, Yuanyuan Jiang, Yizhong Lu, Zhenlu Zhao. (2018) Highly sensitive fluorescent detection of glutathione and histidine based on the Cu(II)-thiamine system. ANALYST, 143 (18): (4442-4447). [PMID:30151530] [10.1039/C8AN01201F]
8. Xiaona Li, Dandan Han, Yan Wang, Shichao Du, Yumin Liu, Jiaqi Zhang, Bo Yu, Baohong Hou, Junbo Gong. (2016) Measurement of Solubility of Thiamine Hydrochloride Hemihydrate in Three Binary Solvents and Mixing Properties of Solutions. JOURNAL OF CHEMICAL AND ENGINEERING DATA, [10.1021/acs.jced.6b00613]
9. Ying Li, Changyin Lv, Qiang Sun, Ying Zhao, Yunjing Li. (2014) Chromatographic characteristics of water-soluble vitamins with irradiation processing and its application. Analytical Methods, 7 (1): (155-160). [10.1039/C4AY01312C]
10. Jinghui Zhu, Shaopu Liu, Zhongfang Liu, Yuanfang Li, Man Qiao, Xiaoli Hu. (2013) Enhanced spectrofluorimetric determination of hypochlorite based on the catalytic oxidation of thiamine to thiochrome in the presence of trace ferrocyanide. RSC Advances, 4 (12): (5990-5994). [10.1039/C3RA46170J]
11. Wenwen Zhu, Jiali Fang, Chenbo Ji, Hong Zhong, Tianying Zhong, Xianwei Cui. (2024) Maternal neonicotinoid pesticide exposure impairs glucose metabolism by deteriorating brown fat thermogenesis. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, [PMID:39709706] [10.1016/j.ecoenv.2024.117596]
12. Jianhui Xin, Chang Shu, Yuxin Fu, Xue Yu, Zhuqing Wang, Xueyuan Zeng, Rui Wang, Tian Meng, Jian Sun, Mengxia Yan. (2024) MOF-confined ultrafine nanozymes with enhanced catalysis for sensitive colorimetric detection of glucose. TALANTA, [PMID:39500180] [10.1016/j.talanta.2024.127152]
13. Taoyue Yuan, Shunke Ding, Fei Xue, Zhenqi Du, Xinyu Yang, Qingzhi Han, Mengtao Ma, Xiaoyan Chen. (2023) Reactivity and reaction pathways of peroxymonosulfate and peroxydisulfate with neonicotinoid insecticides. WATER RESEARCH, [PMID:37976950] [10.1016/j.watres.2023.120852]
14. Zhang Jing-Xian, Lv Chun-Lin, Tang Chang, Jiang Lu-Yao, Wang Ai-Jun, Feng Jiu-Ju. (2022) Ultrasensitive sandwich-typed electrochemical immunoassay for detection of squamous cell carcinoma antigen based on highly branched PtCo nanocrystals and dendritic mesoporous SiO2@AuPt nanoparticles. MICROCHIMICA ACTA, 189 (11): (1-11). [PMID:36219254] [10.1007/s00604-022-05520-1]
15. Lv Yubing, Zhou Yanli, Lv Chaoran, Wang Mengyao, Sheng Nan, Lin Yuanyuan, Wang Cancan, Xu Maotian, Zhang Jing, Yan Mei. (2025) Construction of an “aptamer-target-peptide” Sandwich Electrochemical Biosensor for Ultrasensitive Assay of Amyloid-Beta Oligomers based on Bimetallic Covalent Organic Framework. Journal of Analysis and Testing, [10.1007/s41664-025-00382-x]
16. Haoming Guo, Nan Xiao, Yabo Liang, Xueke Liu, Peng Wang, Donghui Liu. (2025) Neurotoxic impacts of neonicotinoid pesticide residues in Chinese honey on Apis mellifera L.. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, [PMID:40879281] [10.1002/jsfa.70154]
17. Haolin Zhang, Jingjing Zhang, Hui Cao, Petra Högger, Randolph Arroo, Mohamed A. Farag, Avi Shpigelman, Jianbo Xiao, Chunlin Li. (2025) Amination of Flavonoids Possessing a Pyrogallol Group in Cell Culture Medium at 37°C. Food Frontiers, 6 (2): (1058-1078). [10.1002/fft2.70002]
18. Lei Diao, Yang Ma, Liping Wang, Peng Li, Bin Zhang, Weijing Meng, Jingzeng Cai, Yan Meng, Yuxun Zhou, Jingying Zhai, Huijie Chen. (2025) New Insights into Melatonin’s Function on Thiacloprid-Induced Pyroptosis and Inflammatory Response in Head Kidney Lymphocytes of Cyprinus carpio: Implicating Mitochondrial Metabolic Imbalance and mtROS/cGAS-STING/NF-κB Axis. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, [PMID:40238706] [10.1021/acs.jafc.5c01019]
19. Jialin Zhang, Xuan Wang, Ming Zhou, Jinhui Li, Kangqiang Lu, Herui Wen. (2025) Ultrasensitive multifunctional COF electrochemical biosensor for bacteria detection based on triple-helix molecular switch and Zn2+ -triggered DNAzyme-driven swing-arm robot. SENSORS AND ACTUATORS B-CHEMICAL, [10.1016/j.snb.2025.138488]
20. Zhang Jia, Guo Lu-Yao, Lin Xiao-Qian, Wen Gui-Hua, Zhang Xue-Feng, Yu Li-Hong, He Mei-Qian, He Yu-Mei, Zou Long, Zhang Meng-Tian, Cao Li-Ming, He Chun-Ting. (2025) Microbial-vulcanized organic-inorganic dual-modulated cobalt hydroxide for oxygen evolution reaction. Nature Communications, 16 (1): (10766). [PMID:41315433] [10.1038/s41467-025-65807-8]
21. Chunli Li, Zikai Zheng, Shiren Huang, Sujin Zheng, Linyun Zeng, Masrur Khodiev, Utkirjon Holikulov, Mekhrdod S. Kurboniyon, Chunyan Zhou, Jialiang Pan, Xinguo Zhang. (2025) Preparation and luminescent mechanism of dual-emissive red carbon dots for Pb2+/Fe3+ ion sensing and water content detection. JOURNAL OF MOLECULAR LIQUIDS, [10.1016/j.molliq.2025.129067]
22. Tengfei Zhang, Jie Zang, Boming Yang, Qiuxia Wang, Jijun Yan, Peiyong Xin, Jinfang Chu, Huabang Chen, Zhaogui Zhang. (2025) ZmTH1 Is Vital for Healthy Plant Growth and Promotes Cold/Drought Tolerance by Regulating Thiamin Diphosphate-Dependent Metabolisms in Maize. PLANT BIOTECHNOLOGY JOURNAL, [PMID:41078082] [10.1111/pbi.70400]
23. Okkod Abdellateif, Yang Xiaoming. (2026) Dual-mode carbon dots for cefuroxime monitoring in plasma. MICROCHIMICA ACTA, 193 (4): (249). [PMID:41860599] [10.1007/s00604-026-07985-w]
24. Yi Ma, Jiatao Zhang, Cheng Chen, Mengzhi Wang, Haifei Li, Yunfei Deng, Xingru Zhou, Jianhui Hu, Hao Zhang, Guohui Li, Jin Wang, Zhongjian Guo. (2026) Thiamine ameliorates subacute ruminal acidosis–induced mastitis in goats and is associated with modulation of the NF-κB/NLRP3/CLOCK axis and rumen microbial homeostasis. JOURNAL OF DAIRY SCIENCE, [10.3168/jds.2025-27720]