氨基喹啉及其衍生物

描述:

含喹啉环系氨基基团的有机化合物。

上级分类:

有机化合物 ⮕ 有机杂环化合物 ⮕ 喹啉及其衍生物 ⮕ 氨基喹啉及其衍生物

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收藏夹比较

克莱拉尼
CAS: 670220-88-9 分子式: C₂₆H₂₉N₅O₂ 分子量: 443.54

Moligand™ ? ≥98%

有现货货号: C127776

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价格与包装

技术标识符

IUPAC名称

1-[2-[5-[(3-methyloxetan-3-yl)methoxy]benzimidazol-1-yl]quinolin-8-yl]piperidin-4-amine

SMILES

CC1(COC1)COC2=CC3=C(C=C2)N(C=N3)C4=NC5=C(C=CC=C5N6CCC(CC6)N)C=C4

InChIKey

DYNHJHQFHQTFTP-UHFFFAOYSA-N

InChI

1S/C26H29N5O2/c1-26(14-32-15-26)16-33-20-6-7-22-21(13-20)28-17-31(22)24-8-5-18-3-2-4-23(25(18)29-24)30-11-9-19(27)10-12-30/h2-8,13,17,19H,9-12,14-16,27H2,1H3

关联靶标

Electron transfer flavoprotein subunit beta, Macrophage colony-stimulating factor 1 receptor, Serine/threonine-protein kinase 26, Receptor-type tyrosine-protein kinase FLT3, Serine/threonine-protein kinase SIK2, Serine/threonine-protein kinase SIK3, Platelet-derived growth factor receptor alpha, Platelet-derived growth factor receptor beta, MAP/microtubule affinity-regulating kinase 4, Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial, Adenine phosphoribosyltransferase, UMP-CMP kinase, Mast/stem cell growth factor receptor Kit, Glycine--tRNA ligase, Ribosyldihydronicotinamide dehydrogenase [quinone], High affinity nerve growth factor receptor, Obg-like ATPase 1
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CP-673451,PDGFR抑制剂
CAS: 343787-29-1 分子式: C₂₄H₂₇N₅O₂ 分子量: 417.52

Moligand™ ? ≥98%

有现货货号: C125124

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价格与包装

技术标识符

IUPAC名称

1-[2-[5-(2-methoxyethoxy)benzimidazol-1-yl]quinolin-8-yl]piperidin-4-amine

SMILES

COCCOC1=CC2=C(C=C1)N(C=N2)C3=NC4=C(C=CC=C4N5CCC(CC5)N)C=C3

InChIKey

DEEOXSOLTLIWMG-UHFFFAOYSA-N

InChI

1S/C24H27N5O2/c1-30-13-14-31-19-6-7-21-20(15-19)26-16-29(21)23-8-5-17-3-2-4-22(24(17)27-23)28-11-9-18(25)10-12-28/h2-8,15-16,18H,9-14,25H2,1H3

关联靶标

Platelet-derived growth factor receptor alpha, Platelet-derived growth factor receptor beta, Mast/stem cell growth factor receptor Kit
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4-氨基-6-溴喹啉
CAS: 65340-73-0 EC号: 672-826-5 分子式: C₉H₇BrN₂ 分子量: 223.07

≥97%

有现货货号: B135251

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价格与包装

技术标识符

IUPAC名称

6-bromoquinolin-4-amine

SMILES

C1=CC2=NC=CC(=C2C=C1Br)N

InChIKey

FNXZGQRYAJYZLP-UHFFFAOYSA-N

InChI

1S/C9H7BrN2/c10-6-1-2-9-7(5-6)8(11)3-4-12-9/h1-5H,(H2,11,12)
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伯舒替尼 (SKI-606)
CAS: 380843-75-4 EC号: 700-455-1 分子式: C₂₆H₂₉Cl₂N₅O₃ 分子量: 530.45

Moligand™ ? ≥99%

有现货货号: B129905

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价格与包装

技术标识符

IUPAC名称

4-(2,4-dichloro-5-methoxyanilino)-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile

SMILES

CN1CCN(CC1)CCCOC2=C(C=C3C(=C2)N=CC(=C3NC4=CC(=C(C=C4Cl)Cl)OC)C#N)OC

InChIKey

UBPYILGKFZZVDX-UHFFFAOYSA-N

InChI

1S/C26H29Cl2N5O3/c1-32-6-8-33(9-7-32)5-4-10-36-25-13-21-18(11-24(25)35-3)26(17(15-29)16-30-21)31-22-14-23(34-2)20(28)12-19(22)27/h11-14,16H,4-10H2,1-3H3,(H,30,31)

关联靶标

Ephrin type-A receptor 2, Ephrin type-A receptor 4, Ephrin type-A receptor 8, Ephrin type-B receptor 4, Receptor tyrosine-protein kinase erbB-4, Ephrin type-A receptor 5, Receptor tyrosine-protein kinase erbB-3, Epidermal growth factor receptor, Ephrin type-A receptor 3, Proto-oncogene tyrosine-protein kinase Src, Serine/threonine-protein kinase 10, Serine/threonine-protein kinase 24, Serine/threonine-protein kinase 35, Serine/threonine-protein kinase 4, Tyrosine-protein kinase TXK, Tyrosine-protein kinase Yes, Tyrosine-protein kinase FRK, Tyrosine-protein kinase Fyn, Ephrin type-B receptor 2, Cyclin-G-associated kinase, Tyrosine-protein kinase Fgr, Calcium/calmodulin-dependent protein kinase type 1D, Serine/threonine-protein kinase SIK1, Serine/threonine-protein kinase SIK2, TRAF2 and NCK-interacting protein kinase, Serine/threonine-protein kinase SIK3, STE20-like serine/threonine-protein kinase, Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase, Misshapen-like kinase 1, Dual specificity mitogen-activated protein kinase kinase 2, Mitogen-activated protein kinase kinase kinase kinase 2, Mitogen-activated protein kinase kinase kinase 19, Tyrosine-protein kinase Lck, Mitogen-activated protein kinase kinase kinase kinase 1, Mitogen-activated protein kinase kinase kinase kinase 3, Mitogen-activated protein kinase kinase kinase kinase 4, Mitogen-activated protein kinase kinase kinase kinase 5, Tyrosine-protein kinase Lyn, Tyrosine-protein kinase BTK, Cytoplasmic tyrosine-protein kinase BMX, Breakpoint cluster region protein, Tyrosine-protein kinase Blk, Activated CDC42 kinase 1, Tyrosine-protein kinase ABL2, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase HCK, BDNF/NT-3 growth factors receptor, High affinity nerve growth factor receptor, Calcium/calmodulin-dependent protein kinase type II subunit gamma, Dual specificity mitogen-activated protein kinase kinase 1, Dual specificity mitogen-activated protein kinase kinase 5
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2-氨基喹啉
CAS: 580-22-3 EC号: 209-458-8 分子式: C₉H₈N₂ 分子量: 144.17

≥97%(GC)

有现货货号: A136404

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价格与包装

技术标识符

IUPAC名称

quinolin-2-amine

SMILES

C1=CC=C2C(=C1)C=CC(=N2)N

InChIKey

GCMNJUJAKQGROZ-UHFFFAOYSA-N

InChI

1S/C9H8N2/c10-9-6-5-7-3-1-2-4-8(7)11-9/h1-6H,(H2,10,11)
收藏夹比较

阿莫地喹盐酸盐
CAS: 6398-98-7 EC号: 200-706-0 化合物 CID: 64646 分子式: C₂₀H₂₂ClN₃O · 2HCl · 2H₂O 分子量: 464.81

≥97%

有现货货号: A135245

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价格与包装

技术标识符

IUPAC名称

4-[(7-chloroquinolin-4-yl)amino]-2-(diethylaminomethyl)phenol;dihydrate;dihydrochloride

SMILES

CCN(CC)CC1=C(C=CC(=C1)NC2=C3C=CC(=CC3=NC=C2)Cl)O.O.O.Cl.Cl

InChIKey

YVNAYSHNIILOJS-UHFFFAOYSA-N

InChI

1S/C20H22ClN3O.2ClH.2H2O/c1-3-24(4-2)13-14-11-16(6-8-20(14)25)23-18-9-10-22-19-12-15(21)5-7-17(18)19;;;;/h5-12,25H,3-4,13H2,1-2H3,(H,22,23);2*1H;2*1H2
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5-氨基异喹啉盐酸盐
CAS: 58143-00-3 EC号: 633-074-3 化合物 CID: 21567167 分子式: C₉H₉ClN₂ 分子量: 180.638

≥97%

有现货货号: A136406

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价格与包装

技术标识符

IUPAC名称

isoquinolin-5-amine;dihydrochloride

SMILES

C1=CC2=C(C=CN=C2)C(=C1)N.Cl.Cl

InChIKey

YIFMEJRWWQEKPJ-UHFFFAOYSA-N

InChI

1S/C9H8N2.2ClH/c10-9-3-1-2-7-6-11-5-4-8(7)9;;/h1-6H,10H2;2*1H
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2-氨基-8-羟基喹啉
CAS: 70125-16-5 EC号: 628-443-0 分子式: C₉H₈N₂O 分子量: 160.17

≥98%(GC)

有现货货号: A136838

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价格与包装

技术标识符

IUPAC名称

2-aminoquinolin-8-ol

SMILES

C1=CC2=C(C(=C1)O)N=C(C=C2)N

InChIKey

UFVLIVCXTIGACT-UHFFFAOYSA-N

InChI

1S/C9H8N2O/c10-8-5-4-6-2-1-3-7(12)9(6)11-8/h1-5,12H,(H2,10,11)
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培利替尼
CAS: 257933-82-7 EC号: 803-625-4 分子式: C₂₄H₂₃ClFN₅O₂ 分子量: 467.92

Moligand™ ? ≥98%

有现货货号: P125444

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价格与包装

技术标识符

IUPAC名称

(E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide

SMILES

CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)F)Cl)C#N)NC(=O)C=CCN(C)C

InChIKey

WVUNYSQLFKLYNI-AATRIKPKSA-N

InChI

1S/C24H23ClFN5O2/c1-4-33-22-12-20-17(11-21(22)30-23(32)6-5-9-31(2)3)24(15(13-27)14-28-20)29-16-7-8-19(26)18(25)10-16/h5-8,10-12,14H,4,9H2,1-3H3,(H,28,29)(H,30,32)/b6-5+

关联靶标

Epidermal growth factor receptor, Cyclin-G-associated kinase, Tyrosine-protein kinase JAK3, Mitogen-activated protein kinase kinase kinase kinase 5
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来那替尼 (HKI-272)
CAS: 698387-09-6 EC号: 811-237-1 分子式: C₃₀H₂₉ClN₆O₃ 分子量: 557.04

Moligand™ ? ≥99%

有现货货号: N126132

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价格与包装

技术标识符

IUPAC名称

(E)-N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide

SMILES

CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)C=CCN(C)C

InChIKey

JWNPDZNEKVCWMY-VQHVLOKHSA-N

InChI

1S/C30H29ClN6O3/c1-4-39-28-16-25-23(15-26(28)36-29(38)9-7-13-37(2)3)30(20(17-32)18-34-25)35-21-10-11-27(24(31)14-21)40-19-22-8-5-6-12-33-22/h5-12,14-16,18H,4,13,19H2,1-3H3,(H,34,35)(H,36,38)/b9-7+

关联靶标

Receptor tyrosine-protein kinase erbB-4, Receptor tyrosine-protein kinase erbB-3, Receptor tyrosine-protein kinase erbB-2, Epidermal growth factor receptor, Serine/threonine-protein kinase 25, Serine/threonine-protein kinase 26, Serine/threonine-protein kinase 10, Serine/threonine-protein kinase 24, Misshapen-like kinase 1, Dual specificity mitogen-activated protein kinase kinase 2, Mitogen-activated protein kinase kinase kinase 19, Mitogen-activated protein kinase kinase kinase kinase 3, Mitogen-activated protein kinase kinase kinase kinase 5, Dual specificity mitogen-activated protein kinase kinase 1
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NSC 23766,Rac-1抑制剂
CAS: 1177865-17-6 化合物 CID: 16759159 分子式: C₂₄H₃₅N₇·3HCl 分子量: 530.96

≥98%

有现货货号: N129204

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价格与包装

技术标识符

IUPAC名称

6-N-[2-[5-(diethylamino)pentan-2-ylamino]-6-methylpyrimidin-4-yl]-2-methylquinoline-4,6-diamine;trihydrochloride

SMILES

CCN(CC)CCCC(C)NC1=NC(=CC(=N1)NC2=CC3=C(C=C(N=C3C=C2)C)N)C.Cl.Cl.Cl

InChIKey

CPUHORIUXPQCHW-UHFFFAOYSA-N

InChI

1S/C24H35N7.3ClH/c1-6-31(7-2)12-8-9-16(3)27-24-28-18(5)14-23(30-24)29-19-10-11-22-20(15-19)21(25)13-17(4)26-22;;;/h10-11,13-16H,6-9,12H2,1-5H3,(H2,25,26)(H2,27,28,29,30);3*1H
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5-氨基喹啉
CAS: 611-34-7 EC号: 210-266-1 分子式: C₉H₈N₂ 分子量: 144.17

≥97%(T)

有现货货号: A120009

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价格与包装

技术标识符

IUPAC名称

quinolin-5-amine

SMILES

C1=CC(=C2C=CC=NC2=C1)N

InChIKey

XMIAFAKRAAMSGX-UHFFFAOYSA-N

InChI

1S/C9H8N2/c10-8-4-1-5-9-7(8)3-2-6-11-9/h1-6H,10H2