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盐酸硫胺

规格或纯度: AR,99.0%
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货号 (SKU) 包装规格 是否现货 价格 数量
T104100-25g
25g 现货 Stock Image
T104100-100g
100g 现货 Stock Image
T104100-250g
250g 现货 Stock Image
T104100-500g
500g 现货 Stock Image
T104100-2.5kg
2.5kg 现货 Stock Image
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维生素及相关化合物

基本描述

别名 维生素B1 盐酸盐
英文别名 THIAMINE HYDROCHLORIDE|67-03-8|Thiamine HCL|Aneurine hydrochloride|Vitamin B1 hydrochloride|Clotiamina|Eskaphen|Thiamine chloride hydrochloride|Betalin S|Thiamine dichloride|vitamin B1|Begiolan|Bethiazine|Bevitine|Bithiamin|Thiadoxine|Tiamidon|Tiaminal|Vi
规格或纯度 AR,99.0%
英文名称 Thiamine hydrochloride
生化机理 Thiamine Hydrochloride is a cofactor required for oxidation of carbohydrates and for the synthesis of ribose.Thiamine is an essential coenzyme in carbohydrate metabolism. Deficiency of thiamine causes beriberi, a neurological and cardiovascular disease.Thiamine is administered in case of deficiency, either due to reduced intake or synthesis.Congenital defect in the thiamine transporter gene SLC19A2 causes thiamine-responsive megaloblastic anemia syndrome (TRMA). Thiamine mimics acetylcholine in brain and possible exerts a role in Alzheimer′s disease.Thiamine deficiency in ruminants causes polioencephalomalacia.
储存温度 充氩
运输条件 常规运输
产品介绍

Thiamine HCl (Vitamin B1) 是一种水溶性的复合维生素B,它的磷酸盐衍生物参与多个细胞内过程。硫胺素是一种水溶性维生素B复合物。在结构上,它是由五元噻唑环和六元氨基嘧啶环通过甲基连接而成的。硫胺素天然存在于水果、蔬菜、家禽和蛋中。盐酸硫胺素已被用作纯化学物质培养基 和细菌生长培养基的维生素补充剂。

Thiamine or vitamin B1 is a water-soluble vitamin of the B complex, its phosphate derivatives are involved in many cellular processes.Thiamine is a water-soluble vitamin-B complex. Structurally, it possesses a five-membered thiazolium ring and a six-membered amino-pyrimidine ring connected by a methyl group. Thiamine is naturally available in fruits, vegetables, poultry, eggs.
A cofactor required for oxidation of carbohydrates and for the synthesis of ribose.

名称和标识符

EC号 200-641-8
IUPAC Name 2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol;chloride;hydrochloride
INCHI InChI=1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1
InChi Key DPJRMOMPQZCRJU-UHFFFAOYSA-M
Canonical SMILES CC1=C(SC=[N+]1CC2=CN=C(N=C2N)C)CCO.Cl.[Cl-]
Isomeric SMILES CC1=C(SC=[N+]1CC2=CN=C(N=C2N)C)CCO.Cl.[Cl-]
WGK Germany 1
RTECS XI7350000
关联CAS 59-43-8
PubChem CID 6202
分子量 337.27
Beilstein号 3851771
Reaxy-Rn 3851771

化学和物理性质

溶解性 Soluble in water (100 mg/ml), glycerol (1 g/18 ml), 95% ethanol (1 g/100 ml), absolute ethanol (1 g/315 ml), DMSO, and methanol. Insoluble in benzene, hexane, chloroform, and ether.
密度 1.401
敏感性 对光和湿度敏感
熔点 250°C

安全和危险性(GHS)

象形图
ghs07

Harmful

信号词 Warning
危险声明 H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
预防措施声明 P261,P305+P351+P338
WGK Germany 1
RTECS XI7350000
Reaxy-Rn 3851771
Merck Index 9295
个人防护装备 Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

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参考文献

1. Joseph E Kerschner,Edward Horsey,Azad Ahmed,Christy Erbe,Pawjai Khampang,Joseph Cioffi,Fen Ze Hu,James Christopher Post,Garth D Ehrlich.  (2009-01-21)  Gene expression differences in infected and noninfected middle ear complementary DNA libraries..  Archives of otolaryngology--head & neck surgery,  135  ((1)):  (33-39).  [PMID:19153305]
2. Ashish K Singh,Sumeet K Pandey,Gattupalli Naresh Kumar.  (2014-06-17)  Pyrroloquinoline quinone-secreting probiotic Escherichia coli Nissle 1917 ameliorates ethanol-induced oxidative damage and hyperlipidemia in rats..  Alcoholism, clinical and experimental research,  38  ((7)):  (2127-2137).  [PMID:24930470]
3. Sándor Gonda,Attila Kiss-Szikszai,Zsolt Szűcs,Csaba Máthé,Gábor Vasas.  (2014-08-02)  Effects of N source concentration and NH4(+)/NO3(-) ratio on phenylethanoid glycoside pattern in tissue cultures of Plantago lanceolata L.: a metabolomics driven full-factorial experiment with LC-ESI-MS(3.)..  Phytochemistry,  106  ():  (44-54).  [PMID:25081104]
4. Kaori Taguchi,Eiichiro Fukusaki,Takeshi Bamba.  (2014-09-10)  Simultaneous analysis for water- and fat-soluble vitamins by a novel single chromatography technique unifying supercritical fluid chromatography and liquid chromatography..  Journal of chromatography. A,  1362  ():  (270-277).  [PMID:25200530]
5. Ilona Olędzka,Katarzyna Kaźmierska,Alina Plenis,Barbara Kamińska,Tomasz Bączek.  (2014-09-23)  Capillary electromigration techniques as tools for assessing the status of vitamins A, C and E in patients with cystic fibrosis..  Journal of pharmaceutical and biomedical analysis,  102  ():  (45-53).  [PMID:25240158]
6. K Maráková,J Piestanský,E Havránek,P Mikus.  (2014-10-03)  Simultaneous analysis of vitamins B in pharmaceuticals and dietary supplements by capillary electrophoresis hyphenated with triple quadrupole mass spectrometry..  Die Pharmazie,  69  ((9)):  (663-668).  [PMID:25272936]
7. Katherine R Heal,Laura Truxal Carlson,Allan H Devol,E Virginia Armbrust,James W Moffett,David A Stahl,Anitra E Ingalls.  (2014-10-11)  Determination of four forms of vitamin B12 and other B vitamins in seawater by liquid chromatography/tandem mass spectrometry..  Rapid communications in mass spectrometry : RCM,  28  ((22)):  (2398-2404).  [PMID:25303468]
8. Irene Delgado-Blanca,Eulogio J Llorent-Martínez,Antonio Ruiz-Medina,Pilar Ortega-Barrales.  (2014-11-06)  A new approach for automated liquid-liquid extraction in a sequential injection manifold..  Analytical and bioanalytical chemistry,  407  ((2)):  (521-528).  [PMID:25370162]
9. Gabriel B Akanni,James C du Preez,Laurinda Steyn,Stephanus G Kilian.  (2014-11-06)  Protein enrichment of an Opuntia ficus-indica cladode hydrolysate by cultivation of Candida utilis and Kluyveromyces marxianus..  Journal of the science of food and agriculture,  95  ((5)):  (1094-1102).  [PMID:25371280]
10. Miranda Hart,David L Ehret,Angelika Krumbein,Connie Leung,Susan Murch,Christina Turi,Philipp Franken.  (2014-11-14)  Inoculation with arbuscular mycorrhizal fungi improves the nutritional value of tomatoes..  Mycorrhiza,  25  ((5)):  (359-376).  [PMID:25391485]
11. Marcela Cristina de Moraes,Juliana Bosco Santos,Daniel Meira Dos Anjos,Luciana Pereira Rangel,Tuane Cristine Ramos Gonçalves Vieira,Ruin Moaddel,Jerson Lima da Silva.  (2015-01-13)  Prion protein-coated magnetic beads: synthesis, characterization and development of a new ligands screening method..  Journal of chromatography. A,  1379  ():  (1-8).  [PMID:25576041]
12. Nicholas Fowler,Carmelo Tomas,Daniel Baden,Lisa Campbell,Andrea Bourdelais.  (2015-05-20)  Chemical analysis of Karenia papilionacea..  Toxicon : official journal of the International Society on Toxinology,  101  ():  (85-91).  [PMID:25981346]
13. Kris Niño G Valdehuesa,Won-Keun Lee,Kristine Rose M Ramos,Rhudith B Cabulong,JiSoo Choi,Huaiwei Liu,Grace M Nisola,Wook-Jin Chung.  (2015-06-07)  Identification of aldehyde reductase catalyzing the terminal step for conversion of xylose to butanetriol in engineered Escherichia coli..  Bioprocess and biosystems engineering,  38  ((9)):  (1761-1772).  [PMID:26048478]
14. Kangming Tian,Dandan Niu,Xiaoguang Liu,Bernard A Prior,Li Zhou,Fuping Lu,Suren Singh,Zhengxiang Wang.  (2015-07-15)  Limitation of thiamine pyrophosphate supply to growing Escherichia coli switches metabolism to efficient D-lactate formation..  Biotechnology and bioengineering,  113  ((1)):  (182-188).  [PMID:26152364]
15. Vishnupriya Pradeep,Steven W Van Ginkel,Sichoon Park,Thomas Igou,Christine Yi,Hao Fu,Rachel Johnston,Terry Snell,Yongsheng Chen.  (2015-09-26)  Use of Copper to Selectively Inhibit Brachionus calyciflorus (Predator) Growth in Chlorella kessleri (Prey) Mass Cultures for Algae Biodiesel Production..  International journal of molecular sciences,  16  ((9)):  (20674-20684).  [PMID:26404247]
16. Lindsey C Vedder,Joseph M Hall,Kimberly R Jabrouin,Lisa M Savage.  (2015-10-01)  Interactions between chronic ethanol consumption and thiamine deficiency on neural plasticity, spatial memory, and cognitive flexibility..  Alcoholism, clinical and experimental research,  39  ((11)):  (2143-2153).  [PMID:26419807]
17. Laura Inchaurraga,Ana L Martínez-López,Beatrice Cattoz,Peter C Griffiths,Matthey Wilcox,Jeffrey P Pearson,Gemma Quincoces,Iván Peñuelas,Nekane Martin-Arbella,Juan M Irache.  (2018-11-26)  The effect of thiamine-coating nanoparticles on their biodistribution and fate following oral administration..  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences,  128  ():  (81-90).  [PMID:30472222]
18. Dominik Szwajgier,Roman Paduch,Wirginia Kukuła-Koch,Magdalena Polak-Berecka,Adam Waśko.  (2019-09-11)  Study on Biological Activity of Bread Enriched with Natural Polyphenols in Terms of Growth Inhibition of Tumor Intestine Cells..  Journal of medicinal food,  23  ((2)):  (181-190).  [PMID:31503525]
19. Lina M González, Nikita Mukhitov, Christopher A Voigt,.  (2019-12-04)  Resilient living materials built by printing bacterial spores..  Nature chemical biology,  16  ((2)):  ( 126-133 ).  [PMID:31792444]
20. María Eugenia Goya,Feng Xue,Cristina Sampedro-Torres-Quevedo,Sofia Arnaouteli,Lourdes Riquelme-Dominguez,Andrés Romanowski,Jack Brydon,Kathryn L Ball,Nicola R Stanley-Wall,Maria Doitsidou.  (2020-01-16)  Probiotic Bacillus subtilis Protects against α-Synuclein Aggregation in C.\xa0elegans..  Cell reports,  30  ((2)):  (367-380).  [PMID:31940482]
21. Souradeep Basu,Emma L Roberts,Andrew W Jones,Matthew P Swaffer,Ambrosius P Snijders,Paul Nurse.  (2020-02-23)  The Hydrophobic Patch Directs Cyclin B to Centrosomes to Promote Global CDK Phosphorylation at Mitosis..  Current biology : CB,  30  ((5)):  (883-892).  [PMID:32084401]
22. Amy I Yu,Lili Zhao,Kathryn A Eaton,Sharon Ho,Jiachen Chen,Sara Poe,James Becker,Allison Gonzalez,Delaney McKinstry,Muneer Hasso,Jonny Mendoza-Castrejon,Joel Whitfield,Charles Koumpouras,Patrick D Schloss,Eric C Martens,Grace Y Chen.  (2020-04-09)  Gut Microbiota Modulate CD8\xa0T Cell Responses to Influence Colitis-Associated Tumorigenesis..  Cell reports,  31  ((1)):  (107471-107471).  [PMID:32268087]
23. Michael D Charters,Steven M Sait,Katie J Field.  (2020-04-11)  Aphid Herbivory Drives Asymmetry in Carbon for Nutrient Exchange between Plants and an Arbuscular Mycorrhizal Fungus..  Current biology : CB,  30  ((10)):  (1801-1808).  [PMID:32275877]
24. Vittorio Bartoli,Grace A Meaker,Mario di Bernardo,Thomas E Gorochowski.  (2020-05-01)  Tunable genetic devices through simultaneous control of transcription and translation..  Nature communications,  11  ((1)):  (2095-2095).  [PMID:32350250]
25. Amin Espah Borujeni,Jing Zhang,Hamid Doosthosseini,Alec A K Nielsen,Christopher A Voigt.  (2020-10-07)  Genetic circuit characterization by inferring RNA polymerase movement and ribosome usage..  Nature communications,  11  ((1)):  (5001-5001).  [PMID:33020480]
26. Jan Sadoch,Monika Pyc,Anna Urbanowicz,Adam Iglewski,Radosław Pilarski.  (2020-10-11)  High-throughput evolutionary optimization of the induction medium towards recombinant protein production in BY-2 tobacco..  Biotechnology and bioengineering,  118  ((2)):  (676-689).  [PMID:33038011]
27. Alex Steimle,Alessandro De Sciscio,Mareike Neumann,Erica T Grant,Gabriel V Pereira,Hiroshi Ohno,Eric C Martens,Mahesh S Desai.  (2021-06-29)  Constructing a gnotobiotic mouse model with a synthetic human gut microbiome to study host-microbe cross talk..  STAR protocols,  ((2)):  (100607-100607).  [PMID:34179836]
28. Paniz Izadi,Marten Niklas Gey,Nicolas Schlüter,Uwe Schröder.  (2021-08-03)  Bidirectional electroactive microbial biofilms and the role of biogenic sulfur in charge storage and release..  iScience,  24  ((8)):  (102822-102822).  [PMID:34337365]
29. Jürgen W Schönborn,Fiona A Stewart,Kerstin Maas Enriquez,Irfan Akhtar,Andrea Droste,Silvio Waschina,Mathias Beller.  (2021-10-30)  Modeling Drosophila gut microbe interactions reveals metabolic interconnectivity..  iScience,  24  ((11)):  (103216-103216).  [PMID:34712918]
30. Ashish A Kawale,Björn M Burmann.  (2021-11-12)  Characterization of backbone dynamics using solution NMR spectroscopy to discern the functional plasticity of structurally analogous proteins..  STAR protocols,  ((4)):  (100919-100919).  [PMID:34761231]
31. Samir Ahmed El-Shazly,Mohamed Mohamed Ahmed,Zein Shaban Ibrahim,Moamen S Refat.  (2015-03-31)  Synthesis, characterization, and efficacy evaluation of a new anti-diabetic vanadyl(II) thiamine hydrochloride complex in streptozotocin-induced diabetic rats..  International journal of immunopathology and pharmacology,  28  ((2)):  (227-239).  [PMID:25816395]
32. Carlos A Mora,Antoine F Herzog,Renzo A Raso,Wendelin J Stark.  (2015-05-20)  Programmable living material containing reporter micro-organisms permits quantitative detection of oligosaccharides..  Biomaterials,  61  ():  (1-9).  [PMID:25988843]
33. Jaroslav Jenčo,Lenka Kujovská Krčmová,Luboš Sobotka,Vladimír Bláha,Petr Solich,František Švec.  (2020-02-20)  Development of novel liquid chromatography method for clinical monitoring of vitamin B1 metabolites and B6 status in the whole blood..  Talanta,  211  ():  (120702-120702).  [PMID:32070596]
34. Mariusz Dyląg,Rodney J Colon-Reyes,Lukasz Kozubowski.  (2020-06-06)  Titan cell formation is unique to Cryptococcus species complex..  Virulence,  11  ((1)):  (719-729).  [PMID:32498590]
35. Conor La Edwards,Dmitry Malyshev,James P Stratford,Munehiro Asally.  (2021-03-04)  Rapid Detection of Proliferative Bacteria by Electrical Stimulation..  Bio-protocol,  10  ((3)):  (e3508-e3508).  [PMID:33654734]
36. F Veronica Greco,Amir Pandi,Tobias J Erb,Claire S Grierson,Thomas E Gorochowski.  (2021-03-21)  Harnessing the central dogma for stringent multi-level control of gene expression..  Nature communications,  12  ((1)):  (1738-1738).  [PMID:33741937]
37. Ning Yang,Bing Han,Lingtong Liu,Hao Yang,Tai Wang.  (2017-05-20)  Plasma Membrane Preparation from Lilium davidii and Oryza sativa Mature and Germinated Pollen..  Bio-protocol,  ((10)):  (e2297-e2297).  [PMID:34541066]
38. Francisco Díaz-Pascual,Martin Lempp,Kazuki Nosho,Hannah Jeckel,Jeanyoung K Jo,Konstantin Neuhaus,Raimo Hartmann,Eric Jelli,Mads Frederik Hansen,Alexa Price-Whelan,Lars Ep Dietrich,Hannes Link,Knut Drescher.  (2021-11-10)  Spatial alanine metabolism determines local growth dynamics of Escherichia coli colonies..  eLife,  10  ():  ().  [PMID:34751128]