Mouse anti Human DBC-1 Antibody, Monoclonal(3G4-D11-D7), could be used for WB, IF, ICC and so on .
Application:
WB: 1/500-1/1000
ICC/IF: 1/50-1/200
IP: 1/20
Protein Function
Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis. Inhibits SUV39H1 methyltransferase activity.