Armenian Hamster anti Mouse DR5/CD262 Antibody, Monoclonal (MD5-1), could be used for Flow, in vitro induction TRAIL-mediated apoptosis, in vivo induction TRAIL-mediated apoptosis and so on. Application: Flow: Use at an assay dependent concentration. in vitro induction TRAIL-mediated apoptosis: Use at an assay dependent concentration. in vivo induction TRAIL-mediated apoptosis: Use at an assay dependent concentration. Protein Function Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.
MK | Ly98 | KILLER | TRICK2B | CD262 antigen | CD262 | death domain containing receptor for TRAIL/Apo-2L | Death receptor 5 | DR5 | DR5TRICK2B | Fas-like protein | KILLER/DR5 | KILLERapoptosis inducing protein TRICK2A/2B | TNF-related apoptosis-inducing l
规格或纯度
无载体, 无叠氮钠, 已验证, PBS Only, ≥95%(SDS-PAGE), 见COA
宿主种属
亚美尼亚仓鼠(Armenian hamster)
特异性
DR5/CD262
种属反应性
小鼠(Mouse)
免疫原
Mouse DR5-Ig fusion protein
偶联
Unconjugated
克隆类型
单克隆抗体
克隆号
MD5-1
Format
Whole IgG
亚型
Armenian Hamster IgG
轻链亚型
kappa
纯化方法
Protein G purified
浓度
见COA
分子类型
抗体
产品线
生物产品
储存与运输
物理外观
Liquid
储存缓冲液
10mM PBS, pH 7.0
储存条件
2-8°C储存,禁止冷冻
运输条件
低温运输,禁止冷冻
稳定性与储存
4°C 下运输。4°C 长期保存(12 个月)。请勿冷冻。收货后建议分装。
图片
DR5/CD262 Armenian Hamster mAb (Ab100457) - Flow Cytometry Flow Cytometry analysis of 2.5 μg/mL Con A stimulated mouse splenocytes cells (72h) labelling DR5/CD262 with DR5/CD262 Armenian Hamster mAb (Ab100457) conjugated with biotin (right panel) at 5.0 μg/mL for 1 hour at 4°C, compared with Armenian Hamster IgG Isotype Control Antibody (Biotin) (Ab135991) (left panel) and detected with SA-PE (rp156150).
DR5/CD262 Armenian Hamster mAb (Ab100457) - Flow Cytometry Flow Cytometry analysis of 2.5 μg/mL Con A stimulated mouse splenocytes cells (72h) labelling DR5/CD262 (red) with DR5/CD262 Armenian Hamster mAb (Ab100457) conjugated with biotin at 5.0 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Armenian Hamster IgG Isotype Control Antibody (Biotin) (Ab135991). Black - Unlabelled control, cells without incubation with primary antibody.