Positively regulates nitric oxide synthesis in umbilical vein endothelial cells (HUVECs). May be involved in dopamine synthesis. May modify pain sensitivity and persistence. Isoform GCH-1 is the functional enzyme, the potential function of the enzymatically inactive isoforms remains unknown.
宿主种属
小鼠(Mouse)
特异性
GCH1
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
Recombinant full length protein of human GCH1 produced in E.coli.
阳性对照
WB: Rat liver, Jurkat and SH-SY5Y lysates. IHC: Human pancreas, prostate carcinoma tissues.
Store at 4°C short term (1-2 weeks). Store at -20°C long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
图片
GCH1 Mouse mAb (Ab105011) - Western Blot All lanes: GCH1 Mouse mAb (Ab105011) at 1/500 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Mouse IgG H&L (HRP) at 1/5000 dilution
Predicted band size: 28 kDa Observed band size: 29 kDa Exposure time: 120.0 s
GCH1 Mouse mAb (Ab105011) - IHC Immunohistochemical staining of paraffinembedded Human pancreas tissue within the normal limits using GCH1 Mouse mAb (Ab105011). (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH 8.5) at 120°C for 3 min) (1:500).
GCH1 Mouse mAb (Ab105011) - IHC Immunohistochemical staining of paraffinembedded Carcinoma of Human prostate tissue using GCH1 Mouse mAb (Ab105011). (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH 8.5) at 120°C for 3 min) (1:500).