Mouse anti Human Lambda Light chain Antibody, Recombinant (MyM1-Lambda), could be used for IHC and so on. Application IHC: 1/100-1/200 Relevance All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of Kappa to Lambda is 70:30 , the vast majority of which is bound to heavy-chain in immunoglobulin. In normal individuals low levels of free light-chain arepresent in serum (kappa, 1.6-15.2 mg/L; Lambda, 0.4-4.2mg/L), with the occurrence of multiple myeloma or other B-cell malignancies these levels can be greatly elevated and can be found at high levels in the urine (Bence-Jones proteins).
规格
产品名称
Recombinant Lambda Light chain Antibody
别名
免疫球蛋白λ轻链单克隆抗体 | 免疫球蛋白λ轻链单克隆抗体 | 重组 Lambda 轻链抗体
英文别名
Bence Jones protein antibody | BJP antibody | Constant region of lambda light chains antibody | Ig lambda chain C regions antibody | ig lambda-6 chain C region antibody | IGLC 1 antibody | IGLC 2 antibody | IGLC 3 antibody | IGLC antibody | IGLC1 antibody
Recombinant Lambda Light chain Antibody (Ab112610) - IHC Immunohistochemistry analysis of paraffin-embedded human tonsil tissue labelling Lambda Light chain with Recombinant Lambda Light chain Antibody (Ab112610) at 1/200 dilution. The section was incubated with Ab112610 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.