Mouse anti Human Langerin Antibody, Recombinant (MyM1-CD207), could be used for IHC and so on. Application IHC: 1/100-1/200 Protein Function Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.
规格
产品名称
Recombinant Langerin Antibody
别名
朗格素单克隆抗体 | 重组 Langerin 抗体
英文别名
C type lectin domain family 4 member K antibody | C-type lectin domain family 4 member K antibody | CD 207 antibody | CD207 antibody | CD207 antigen antibody | CD207 antigen, langerin antibody | CD207 molecule antibody | CLC4K_HUMAN antibody | CLEC 4K ant
Recombinant Langerin Antibody (Ab112770) - IHC Immunohistochemistry analysis of paraffin-embedded human skin tissue labelling Langerin with Recombinant Langerin Antibody (Ab112770) at 1/100 dilution. The section was incubated with Ab112770 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.